Delayed onset muscle soreness: Involvement of neurotrophic factors.
Kasugai, Japan. In J Physiol Sci, Nov 2015
With our model we have found that two pathways are involved in inducing mechanical hyperalgesia after LC: activation of the B2 bradykinin receptor-nerve growth factor (NGF) pathway and activation of the COX-2-glial cell line-derived neurotrophic factor (GDNF) pathway.
Overcoming the blood-brain tumor barrier for effective glioblastoma treatment.
Amsterdam, Netherlands. In Drug Resist Updat, Mar 2015
We provide an overview on methods to overcome the BBTB, including osmotic blood-brain barrier disruption (BBBD), bradykinin receptor-mediated BBTB opening, inhibition of multidrug efflux transporters, receptor-mediated transport systems and physiological circumvention of the BBTB.
Roles of kinins in the nervous system.
São Paulo, Brazil. In Cell Transplant, 2014
This peptide is also an important player in spinal cord injury pathophysiology and recovery, in which bradykinin receptor blockers represent substantial therapeutic potential.
Expression patterns of kinin-dependent genes in endometrial cancer.
Sosnowiec, Poland. In Int J Gynecol Cancer, 2012
The transcriptional activity of the B1 receptor for kinins increased in patients with grade 1 and grade 2 endometrial cancer when compared to the control group, whereas it decreased in patients with grade 3 endometrial cancer.