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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

BCL2-like 10

Boo, DIVA, BCL2L10, Bcl-B
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, bcl-2, HAD, V1a, Phosphogluconate Dehydrogenase
Papers using Boo antibodies
Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes.
Supplier
Pi Jingbo et al., In Environmental Health Perspectives, 2010
... positive) was determined by statistical analysis of the various dot plots with the BD FACS Diva, version 6.1.2
Phase I trial to determine the dose range for the c-Met inhibitor ARQ197 that inhibits c-Met and FAK phosphorylation, when administered by an oral twice-a-day schedule.
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Aziz Syed, In PLoS ONE, 2007
... Antigen retrieval was performed with DIVA decloaker antigen retrieval buffer (Biocare medical, Concord, CA) in a decloaking ...
IFN-g production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
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Zheng Song Guo, In PLoS ONE, 2004
... Stained cells were measured on LSRII with FACS Diva Software (BD Biosciences).
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
Supplier
Stoddart Cheryl A., In PLoS ONE, 2000
... (CD3, CD14, CD16, CD19, CD20, and CD56), (all antibodies from BD), then FACS sorted (FACS Diva, Becton Dickinson).
Centromeric Repositioning of Coreceptor Loci Predicts Their Stable Silencing and the CD4/CD8 Lineage Choice
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Brown Karen E. et al., In The Journal of Experimental Medicine, 1999
... CD4-PE/Cy5, CD8a-PE (Caltag Laboratories), and in some experiments CD69-FITC (BD Biosciences), and sorted on a FACS DIVA (Becton Dickinson) and subjected to fluorescence ...
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Papers on Boo
Foot-and-mouth disease vaccines: progress and problems.
New
Liu et al., Lanzhou, China. In Expert Rev Vaccines, Feb 2016
Vaccines may sometimes contain traces of FMD viral non-structural proteins (NSPs), therefore, interfering with the NSP-based serological differentiation infected from vaccinated animals (DIVA).
The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction.
New
Purves et al., Durham, United States. In J Urol, Jan 2016
PURPOSE: While bladder outlet obstruction (BOO) is well-established to elicit an inflammatory reaction in the bladder that leads to overactive bladder and fibrosis, little is known about the mechanism by which this is initiated.
Alteration of Urothelial Inflammation, Apoptosis, and Junction Protein in Patients with Various Bladder Conditions and Storage Bladder Symptoms Suggest Common Pathway Involved in Underlying Pathophysiology.
New
Kuo et al., Taiwan. In Low Urin Tract Symptoms, May 2015
METHODS: Bladder tissues were obtained from patients with LUTD including 17 with interstitial cystitis/bladder pain syndrome (IC/BPS), 15 with bladder outlet obstruction (BOO), 12 with spinal cord injury (SCI), 12 with recurrent urinary tract infection (UTI), 13 with ketamine related cystitis (KC) and 10 controls.
An update on the pharmacotherapy for lower urinary tract dysfunction.
Review
Goldman et al., United States. In Expert Opin Pharmacother, 2015
At the level of the outlet, there can be decreased resistance resulting in stress urinary incontinence (SUI) or increased resistance resulting in bladder outflow obstruction (BOO).
Effect of the Chinese traditional prescription Suo Quan Wan on TRPV1 expression in the bladder of rats with bladder outlet obstruction.
Cao et al., Guangzhou, China. In Bmc Complement Altern Med, 2014
This study investigated the effect of SQW on bladder function and transient receptor potential vanilloid 1 (TRPV1) expression in the bladder of rats with bladder outlet obstruction (BOO).
Dual function of the hemagglutinin H5 fused to chicken CD154 in a potential strategy of DIVA against avian influenza disease: preliminary study.
López et al., Havana, Cuba. In Open Vet J, 2014
In this study we demonstrated that the vaccine candidate against avian influenza virus H5N1 based on the hemagglutinin H5 (HA) fused to the chicken CD154 (HACD) can also be used for differentiating infected from vaccinated animals (DIVA).
The challenges of classical swine fever control: modified live and E2 subunit vaccines.
Review
Chang et al., Taipei, Taiwan. In Virus Res, 2014
Although MLV provide earlier and more complete protection than E2 subunit vaccines, it has the drawback of not allowing differentiation between infected and vaccinated animals (DIVA).
An rfaH Mutant of Salmonella enterica Serovar Typhimurium is Attenuated in Swine and Reduces Intestinal Colonization, Fecal Shedding, and Disease Severity Due to Virulent Salmonella Typhimurium.
Lee et al., Ames, United States. In Front Vet Sci, 2013
These results indicate that vaccination of swine with the attenuated rfaH mutant confers protection against challenge with virulent S. Typhimurium but does not interfere with herd level monitoring for Salmonella spp., thereby allowing for differentiation of infected from vaccinated animals (DIVA).
[Progress in new-type vaccines against classical swine fever].
Review
Qiu et al., Harbin, China. In Sheng Wu Gong Cheng Xue Bao, 2013
Immunization failure has been reported frequently and it is difficult to distinguish between wild-type infected and vaccinated animals (DIVA).
Virus-like particles: promising platforms with characteristics of DIVA for veterinary vaccine design.
Review
Wang et al., Changchun, China. In Comp Immunol Microbiol Infect Dis, 2013
DIVA (differentiating infected from vaccinated animals) vaccine, originally known as marker vaccine, usually based on the absence of at least one immunogenic protein in the vaccine strain, allows DIVA in conjunction with a diagnostic test that detects antibodies against the antigens lacking in the vaccine strain.
Effects of Oral Rho Kinase Inhibitor Fasudil on Detrusor Overactivity after Bladder Outlet Obstruction in Rats.
Choo et al., Taegu, South Korea. In Low Urin Tract Symptoms, 2013
OBJECTIVES: Bladder outlet obstruction (BOO)-related detrusor hypertrophy is associated with upregulation of Rho-kinase (ROCK) activity in an experimental animal model, and has been implicated in BOO-induced bladder dysfunction.
The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.
GeneRIF
Luciano et al., Nice, France. In Autophagy, 2012
Bcl-B interacts with the BH3 domain of BECN1 and Bcl-B overexpression reduces autophagy triggered by a variety of pro-autophagic stimuli.
BCL2L10 is a predictive factor for resistance to azacitidine in MDS and AML patients.
GeneRIF
Auberger et al., Nice, France. In Oncotarget, 2012
expression is predictive of azacitidine-resistance in myelodysplastic syndrome patients
Potential Biomarkers Utilized to Define and Manage Overactive Bladder Syndrome.
Kuo, Taiwan. In Low Urin Tract Symptoms, 2012
Evidence has also shown that urinary proteins, such as nerve growth factor (NGF) and prostaglandin E2 (PGE2 ) levels increase in patients with OAB, bladder outlet obstruction (BOO) and DO.
Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.
GeneRIF
Varmus et al., Bethesda, United States. In Proc Natl Acad Sci U S A, 2012
Ubqln stabilizes BCLb protein, while also promoting monoubiquitination on multiple lysine residues and relocation to the cytosol.
Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-azacytidine.
GeneRIF
Leone et al., In Leukemia, 2011
BCL2L10 methylation is associated with myelodysplastic syndromes.
Selective Bcl-2 Inhibitor Probes
Review
Sklar et al., Bethesda, United States. In Unknown Journal, 2011
This probe report describes the identification and development of an inhibitor of Bcl-B, a member of the Bcl-2 family.
Urethral Sensations are Related to the Development of Detrusor Overactivity.
Akino et al., Fukui, Japan. In Low Urin Tract Symptoms, 2011
Clinical findings have led to the assumption that bladder outlet obstruction (BOO) caused by benign prostatic enlargement (BPE) induces storage symptoms and detrusor overactivity.
Characterization of a novel interaction between Bcl-2 members Diva and Harakiri.
GeneRIF
de Alba et al., Madrid, Spain. In Plos One, 2009
analysis of a novel interaction between Bcl-2 members Diva and Harakiri
Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm.
Review
Impact
Hsueh et al., Stanford, United States. In Physiol Rev, 2000
In contrast, the channel-forming Mcl-1 and Bok regulate cytochrome c release and, together with the recently discovered Diva/Boo, control downstream apoptosis-activating factor (Apaf)-1 homologs and caspases.
More papers using Boo antibodies
Generation of a novel Fli-1 protein by gene targeting leads to a defect in thymus development and a delay in Friend virus-induced erythroleukemia
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Sreenath Taduru L. et al., In Journal of Cancer, 1995
... was collected on the total cell population and the analysis was performed by using FACS Diva software (version 5 .03)
Finding Groups in Data: An Introduction to Cluster Analysis.
Supplier
Unutmaz Derya, In PLoS ONE, 1989
... using a FACS Aria (BD Biosciences, Immunocytometry, San Jose, USA) and data were analyzed using FACS DIVA software (BD Biosciences).
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