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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Bone morphogenetic protein 2

bone morphogenetic protein-2
Top mentioned proteins: CAN, HAD, Osteocalcin, ACID, V1a
Papers on bone morphogenetic protein-2
Monolithic calcium phosphate/poly(lactic acid) composite versus calcium phosphate-coated poly(lactic acid) for support of osteogenic differentiation of human mesenchymal stromal cells.
Habibovic et al., Enschede, Netherlands. In J Mater Sci Mater Med, Mar 2016
Enzymatic alkaline phosphatase activity as well as the mRNA expression of bone morphogenetic protein-2, osteopontin and osteocalcin were higher on the composite and coated polymer as compared to the PLA control, while no significant differences were observed between the two methods of combining CaP and PLA.
Repair of a Complicated Calvarial Defect: Reconstruction of an Infected Wound With rhBMP-2.
Losee et al., Pittsburgh, United States. In Ann Plast Surg, Feb 2016
The purpose of this study was to compare the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2)-mediated bone regeneration with the current standard of autologous bone graft for repair of previously infected calvarial defects.
Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation.
Wu et al., Linhai, China. In Genetics, Feb 2016
However, in Cdc42 mutant limb buds, loss of Cdc42 in mesenchymal progenitors led to marked inactivation of p38 and Smad1/5, and in micromass cultures, Cdc42 lied on the upstream of p38 to activate Smad1/5 in bone morphogenetic protein-2-induced mesenchymal condensation.
A review on carrier systems for bone morphogenetic protein-2.
Sinha et al., Ahmadābād, India. In J Biomed Mater Res B Appl Biomater, Feb 2016
UNASSIGNED: Bone morphogenetic protein-2 (BMP-2) has unique bone regeneration property.
The effect of rhBMP-2 in a novel, non-instrumented extremity nonunion model.
Hsu et al., Chicago, United States. In J Orthop Sci, Jan 2016
We developed a non-displaced rat ulna fracture model in order to examine the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2) with an absorbable collagen sponge (ACS) for nonunion treatment.
A self-setting iPSMSC-alginate-calcium phosphate paste for bone tissue engineering.
Xu et al., Baltimore, United States. In Dent Mater, Jan 2016
METHODS: iPSMSCs were pre-osteoinduced for 2 weeks (OS-iPSMSCs), or transduced with bone morphogenetic protein-2 (BMP2-iPSMSCs).
Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration.
Lee et al., Seoul, South Korea. In Osteoarthritis Cartilage, Aug 2015
Upregulation of the genes interleukin 1 beta (IL-1β), p53, p16, p21, and p38 mitogen-activated protein kinase (MAPK) is responsible for the direct induction of senescence, whereas downregulation of the genes transforming growth factor-beta (TGF-β), bone morphogenetic protein-2 (BMP-2), SRY (sex determining region Y)-box 9 (SOX9), and insulin-like growth factor-1 (IGF-1), indirectly induces senescence.
A Systematic Review of Lumbar Fusion Rates With and Without the Use of rhBMP-2.
Mroz et al., Philadelphia, United States. In Spine (phila Pa 1976), Aug 2015
OBJECTIVE: To evaluate literature comparing fusion rates in anterior lumbar interbody fusion (ALIF), posterior lumbar interbody/transforaminal lumbar interbody fusion (PLIF/TLIF), and posterolateral lumbar fusion (PLF) with and without recombinant human bone morphogenetic protein-2 (rhBMP-2).
Quality and Quantity of Published Studies Evaluating Lumbar Fusion during the Past 10 Years: A Systematic Review.
Norvell et al., Portland, United States. In Global Spine J, Jun 2015
Fusion studies designed specifically to evaluate recombinant human bone morphogenetic protein-2 or other bone substitutes, revision surgery studies, nonrandomized comparison studies, case reports, case series, and cost-effectiveness studies were excluded.
Anterior lumbar spine surgery: a systematic review and meta-analysis of associated complications.
Vaccaro et al., Philadelphia, United States. In Spine J, Jun 2015
Predictors used were the type of procedure (open, minimally invasive, or laparoscopic), the approach used (transperitoneal vs. retroperitoneal), use of recombinant bone morphogenetic protein-2, use of preoperative computed tomography angiography (CTA), and the utilization of an access surgeon.
Straight talk with...Harlan Krumholz.
Khamsi et al., In Nat Med, 2014
Under the agreement-the most comprehensive industry-academic partnership of its kind-YODA will independently review and make decisions about requests to access de-identified, patient-level data from the clinical studies supporting all of J&J's approved drugs.It's a major step forward for YODA, which was born in 2011 out of an initial project with the global drug and device manufacturer Medtronic, which is headquartered in Minneapolis, to release data from studies of the company's Infuse product, which contains recombinant human bone morphogenetic protein-2, used to promote bone formation.
Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing.
Hubbell et al., Lausanne, Switzerland. In Science, 2014
By fusing this domain to the GFs vascular endothelial growth factor-A, platelet-derived growth factor-BB, and bone morphogenetic protein-2, we generated engineered GF variants with super-affinity to the ECM.
Bmp signaling is necessary and sufficient for ventrolateral endoderm specification in Xenopus.
Baker et al., Berkeley, United States. In Dev Dyn, 2008
Bmp antagonists and morpholinos designed against Bmp4, Bmp2, and Bmp7 demonstrate that Bmp signaling is critical for ventral, but not dorsoanterior endoderm formation
Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos.
De Robertis et al., Los Angeles, United States. In Development, 2005
Bone morphogenetic protein inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.
BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect.
Olson et al., Seattle, United States. In Nat Med, 2003
We also identified bone morphogenetic protein-2 (BMP-2) as a candidate mediator of retinoid activity.
Repair of bone defects using synthetic mimetics of collagenous extracellular matrices.
Hubbell et al., Zürich, Switzerland. In Nat Biotechnol, 2003
Gels used to deliver recombinant human bone morphogenetic protein-2 (rhBMP-2) to the site of critical- sized defects in rat crania were completely infiltrated by cells and were remodeled into bony tissue within five weeks.
Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide)
Schwendeman et al., Columbus, United States. In Nat Biotechnol, 2000
We successfully applied this stabilization approach in both cylinder- and microsphere-injectable configurations and for delivery of angiogenic basic fibroblast growth factor and bone-regenerating bone morphogenetic protein-2.
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