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Retinoblastoma binding protein 9

Bog, RBBP9
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, MOG, C-4
Papers on Bog
A Genome-Wide Scan of DNA Methylation Markers for Distinguishing Monozygotic Twins.
Cong et al., Shijiazhuang, China. In Twin Res Hum Genet, Dec 2015
Genes associated with these markers are related with cell proliferation, differentiation, and growth and development, including zinc finger proteins, PRRX2, RBBP9, or are involved in G-protein signaling, such as the regulator of G-protein signaling 16.
Mining for Nonribosomal Peptide Synthetase and Polyketide Synthase Genes Revealed a High Level of Diversity in the Sphagnum Bog Metagenome.
Berg et al., Graz, Austria. In Appl Environ Microbiol, Aug 2015
Sphagnum bog ecosystems are among the oldest vegetation forms harboring a specific microbial community and are known to produce an exceptionally wide variety of bioactive substances.
Effect of resveratrol on restoring spermatogenesis in experimental cryptorchid mice and analysis of related differentially expressed proteins.
Li et al., Zhumadian, China. In Cell Biol Int, Jun 2015
In addition, proteomic analysis between the 20 μg/g/day resveratrol-treated group and the control group was carried out, and five kinds of proteins (BAF250, ZFP261, CHD1L, RBBP9, and SOHLH2) were identified.
BOG: R-package for Bacterium and virus analysis of Orthologous Groups.
Lin et al., South Korea. In Comput Struct Biotechnol J, 2014
BOG (Bacterium and virus analysis of Orthologous Groups) is a package for identifying groups of differentially regulated genes in the light of gene functions for various virus and bacteria genomes.
The effect of Cree traditional medicinal teas on the activity of human cytochrome P450-mediated metabolism.
Foster et al., Ottawa, Canada. In J Ethnopharmacol, 2014
ETHNOPHARMACOLOGICAL RELEVANCE: Rhododendron groenlandicum (Bog Labrador tea), Rhododendron tomentosum (Marsh Labrador tea) and Juniperus communis (Juniper) are used in medicinal teas by Canadian aboriginal cultures alone and in combination with conventional drug products.
Molecular and functional characterization of CpACS27A gene reveals its involvement in monoecy instability and other associated traits in squash (Cucurbita pepo L.).
Jamilena et al., Almería, Spain. In Planta, 2014
CpACS27A was sequenced in Bolognese (Bog) and Vegetable Spaghetti (Veg), two monoecious inbred lines whose F2 was segregating for partial andromonoecy.
N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes.
Eliezer et al., New York City, United States. In J Biol Chem, 2014
We report the effects of N-terminal acetylation on α-synuclein binding to lipid vesicles of different composition and curvature and to micelles composed of the detergents β-octyl-glucoside (BOG) and SDS.
Glutathione deficiency in Gclm null mice results in complex I inhibition and dopamine depletion following paraquat administration.
Patel et al., Aurora, United States. In Toxicol Sci, 2013
823, 1-10; McCormack, A. L., Thiruchelvam, M., Manning-Bog, A. B., Thiffault, C., Langston, J. W., Cory-Slechta, D. A., and Di Monte, D. A. [2002].
ABL1 in thalamus is associated with safety but not fear learning.
Lamprecht et al., Haifa, Israel. In Front Syst Neurosci, 2012
The levels of ABL1, Bog, IL1B, and Tau proteins in thalamus were found to be lower in the group trained for safety learning compared to the fear conditioning group 6 h after training.
Bog bilberry anthocyanin extract improves motor functional recovery by multifaceted effects in spinal cord injury.
Liu et al., Beijing, China. In Neurochem Res, 2012
The aim of this study was to determine the therapeutic efficiency of bog bilberry anthocyanin extract (BBAE) treatment starting 1 d after spinal cord injury (SCI) in rats and to investigate the underlying mechanism.
Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancers.
Tong et al., New York City, United States. In Protein Pept Lett, 2012
Structure- function studies of RBBP9 suggest possible routes for novel cancer drug discovery programs.
Two potential biomarkers identified in mesenchymal stem cells and leukocytes of patients with sporadic amyotrophic lateral sclerosis.
Weil et al., Tel Aviv-Yafo, Israel. In Dis Markers, 2011
blood samples of lateral sclerosis patients were found to have significantly different levels of expression of CyFIP2 and RbBP9 compared to the levels of expression in control subjects.
Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance.
Eaves et al., Vancouver, Canada. In Exp Hematol, 2011
Data identified RBBP4 and RBBP9 as required for maintenance of multiple PS cell types, and both RBBPs were bound to RB in PS cells.
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.
Cheresh et al., San Diego, United States. In Proc Natl Acad Sci U S A, 2010
identify RBBP9 as a tumor-associated serine hydrolase that displays elevated activity in pancreatic carcinomas. RBBP9 promotes pancreatic carcinogenesis.
Probe Report for RBBP9 Inhibitors - Probe 2
Rosen et al., Bethesda, United States. In Unknown Journal, 2009
The enzyme RB binding protein 9 (RBBP9) is widely expressed in different tissues and upregulated in certain tumors.
Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.
Cravatt et al., Los Angeles, United States. In Nat Biotechnol, 2009
Using this method, we identify the bioactive alkaloid emetine as a selective inhibitor of the uncharacterized cancer-associated hydrolase RBBP9.
Probe Report for RBBP9 Inhibitors - Probe 1
Rosen et al., Bethesda, United States. In Unknown Journal, 2009
The enzyme, RB binding protein 9 (RBBP9), is widely expressed in a number of different tissues and is upregulated in certain tumors.
Crystal structure of human retinoblastoma binding protein 9.
Tong et al., New York City, United States. In Proteins, 2009
The crystal structure of human RBBP9 has been determined at 1.72 A resolution by the seleno-methionyl single-wavelength anomalous diffraction method.
A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability.
Thorgeirsson et al., Bethesda, United States. In Nat Genet, 1998
Here we describe a new gene, Bog (for B5T over-expressed gene), which was identified and shown to be overexpressed in several transformed rat liver epithelial (RLE) cell lines resistant to the growth-inhibitory effect of TGF-beta1, as well as in primary human liver tumours.
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