The Mendelian colorectal cancer syndromes.
Oxford, United Kingdom. In Ann Clin Biochem, Nov 2015
Most of the approximately 13 high-penetrance genes that predispose to CRC primarily predispose to colorectal polyps, and each gene is associated with a specific type of polyp, whether conventional adenomas (APC, MUTYH, POLE, POLD1, NTHL1), juvenile polyps (SMAD4, BMPR1A), Peutz-Jeghers hamartomas (LKB1/STK11) and mixed polyps of serrated and juvenile types (GREM1).
Bmpr1a Signaling in Cartilage Development and Endochondral Bone Formation.
Chengdu, China. In Vitam Horm, 2014
The type IA bone morphogenetic protein receptor (Bmpr1a), encoded by 11 exons and spanning about 40 kb on chromosome 14 in mice and chromosome 10 in human (Derynck & Feng, 1997; Mishina, Hanks, Miura, Tallquist, & Behringer, 2002), is an essential receptor for BMP signaling.
Oligomeric interactions of TGF-β and BMP receptors.
Tel Aviv-Yafo, Israel. In Febs Lett, 2012
generation of TGF-beta and BMP receptor homo- and hetero-oligomers and its roles as a mechanism capable of fast regulation of signaling by these crucial cytokines [review]