Growth and differentiation factors for periodontal regeneration: a review on factors with clinical testing.
Århus, Denmark. In J Periodontal Res, 2012
RESULTS: Growth and differentiation factor technologies intended for periodontal wound healing/regeneration and evaluated clinically included platelet-derived growth factor, insulin-like growth factor-I and -II, basic fibroblast growth factor, bone morphogenetic protein-3 and growth differentiation factor-5; platelet-derived growth factor was the only Food and Drug Administration-approved commercially available growth and differentiation factor technology.
BMP and BMP inhibitors in bone.
Boston, United States. In Ann N Y Acad Sci, 2006
To date, inhibin and BMP-3 have been identified as BMP receptor antagonists that can block BMP signaling in bone.
Bone morphogenetic proteins.
Rochester, United States. In Growth Factors, 2004
The activity of BMPs was first identified in the 1960s (Urist, M.R. (1965) "Bone formation by autoinduction", Science 150, 893-899), but the proteins responsible for bone induction remained unknown until the purification and sequence of bovine BMP-3 (osteogenin) and cloning of human BMP-2 and 4 in the late 1980s (Wozney, J.M. et al. (1988) "Novel regulators of bone formation: molecular clones and activities", Science 242, 1528-1534; Luyten, F.P. et al. (1989) "Purification and partial amino acid sequence of osteogenin, a protein initiating bone differentiation", J. Biol.