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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Fatty acid binding protein 7, brain

BLBP, FABP7, B-FABP, MRG
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, FABP, CAN, Glial Fibrillary Acidic Protein, HAD
Papers on BLBP
Effects of the mas-related gene (Mrg) C receptor agonist BAM6-22 on nociceptive reflex activity in naive, monoarthritic and mononeuropathic rats after intraplantar and intrathecal administration.
New
Herrero et al., Aachen, Germany. In Eur J Pharmacol, Feb 2016
MrgC receptors are selectively expressed on peripheral and central terminals of small calibre nociceptive fibres.
Regulation of nucleus accumbens transcript levels in mice by early-life social stress and cocaine.
New
Carola et al., Roma, Italy. In Neuropharmacology, Jan 2016
We characterized 4 candidates with regard to their significant neurobiological relevance (ZIC1, ZIC2, FABP7, and PRDM12) and measured their expression in the NAC by immunohistochemistry.
Synthesis of FMRFaNV, a Photoreleasable Caged Transmitter Designed to Study Neuron-Glia Interactions in the Central Nervous System.
New
Bochet et al., Fribourg, Switzerland. In Bioconjug Chem, Jan 2016
For this, we expressed an exogeneous orphan Gq-coupled protein of the Mas-related-gene (Mrg) family in glial cells and generated an MrgR's agonist peptide (FMRFa) that was chemically caged with a nitroveratryl photolabile protecting group (NV).
So-Called "Massive" Retinal Gliosis: A Critical Review and Reappraisal.
Review
New
Proia et al., Durham, United States. In Surv Ophthalmol, Jan 2016
UNASSIGNED: Massive retinal gliosis (MRG), a non-neoplastic retinal glial proliferation, was first described in detail over 25 years ago before the era of immunohistochemistry in a series of 38 cases, to which can be added 30 case reports or small series (no more than 3 cases) subsequently.
Mapping of brain lipid binding protein (Blbp) in the brain of adult zebrafish, co-expression with aromatase B and links with proliferation.
New
Pellegrini et al., Sainte-Foy-lès-Lyon, France. In Gene Expr Patterns, Dec 2015
In zebrafish, radial glial cells display well-established markers such as the estrogen-synthesizing enzyme (AroB) and the brain lipid binding protein (Blbp), which is known to strongly bind omega-3 polyunsaturated fatty acids such as docosahexaenoic acid (DHA).
Restricted distribution of mrg-1 mRNA in C. elegans primordial germ cells through germ granule-independent regulation.
New
Sakamoto et al., Kōbe, Japan. In Genes Cells, Nov 2015
The chromodomain protein MRG-1 is an essential maternal factor for proper germline development that protects germ cells from cell death in C. elegans.
Impaired APP activity and altered Tau splicing in embryonic stem cell-derived astrocytes obtained from an APPsw transgenic minipig.
New
Hyttel et al., Frederiksberg, Denmark. In Dis Model Mech, Nov 2015
These cells were confirmed to co-express varying neural markers, including NES, GFAP and BLBP, typical of type one radial glial cells (RGs) from the subgranular zone.
Effects of frequency-dependent membrane capacitance on neural excitability.
New
Grill et al., Durham, United States. In J Neural Eng, Oct 2015
APPROACH: We implemented a model of c(f) using linear circuit elements, and incorporated it into several models of neurons with different channel kinetics: the Hodgkin-Huxley model of an unmyelinated axon, the McIntyre-Richardson-Grill (MRG) of a mammalian myelinated axon, and a model of a cortical neuron from prefrontal cortex (PFC).
Long-Term Effect of Docosahexaenoic Acid Feeding on Lipid Composition and Brain Fatty Acid-Binding Protein Expression in Rats.
New
Godbout et al., Edmonton, Canada. In Nutrients, Oct 2015
Finally, our data indicate that brain fatty acid binding protein (FABP7), a marker of neural stem cells, is down-regulated in the brains of six-week pups with a high DHA:AA ratio.
Fabrication of New Thermo-pH Responsive Carbon Nanotube Gels.
New
Gopalan et al., In J Nanosci Nanotechnol, Sep 2015
In this work, we have demonstrated the preparation of new multiwall carbon nanotube (MWNT) incorporate multi-responsive (pH and thermal) gels (MWNT-IPN-MRG) though network formation with functional macromolecules that interact each other via hydrogen bonds, covalent networking and temporary associative forces.
Fatty acid binding proteins: tissue-specific functions in health and disease.
Review
Plant et al., Guildford, United Kingdom. In Curr Opin Clin Nutr Metab Care, 2014
RECENT FINDINGS: Dysregulated FABPs have been associated with a number of diseases, including obesity and nonalcoholic fatty liver disease (FABP1, FABP2, FABP4), cardiovascular risk (FABP3) and cancer (FABP5, FABP7).
Interaction of brain fatty acid-binding protein with the polyunsaturated fatty acid environment as a potential determinant of poor prognosis in malignant glioma.
Review
Godbout et al., Edmonton, Canada. In Prog Lipid Res, 2013
This fatty acid-dependent effect on cell migration is dependent on expression of the brain fatty acid binding protein (FABP7) previously shown to bind DHA and AA.
Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer.
GeneRIF
Green et al., Nottingham, United Kingdom. In Breast Cancer Res Treat, 2012
Considerable heterogeneity in expression patterns of FABP7 within breast cancer elates to differences in biological behaviour especially in basal-like breast cancer.
The effects of Fabp7 and Fabp5 on postnatal hippocampal neurogenesis in the mouse.
GeneRIF
Osumi et al., Sendai, Japan. In Stem Cells, 2012
The data suggest that Fabp7 and Fabp5 have differential roles for proliferation and survival of the NSCs/NPCs during postnatal dentate gyrus neurogenesis.
Neural stem cell specific fluorescent chemical probe binding to FABP7.
GeneRIF
Chang et al., Singapore, Singapore. In Proc Natl Acad Sci U S A, 2012
identified its binding target by proteomic analysis as fatty acid binding protein 7 (FABP7), also known as brain lipid binding protein) which is highly expressed in neural stem cells and localized in the cytoplasm
Regulation of the FABP7 gene by PAX6 in malignant glioma cells.
GeneRIF
Godbout et al., Edmonton, Canada. In Biochem Biophys Res Commun, 2012
These data provide the first evidence of direct transactivation of the FABP7 proximal promoter by PAX6 and suggest a synergistic mechanism for PAX6 and other co-factor(s) in regulating FABP7 expression in malignant glioma.
Time of day regulates subcellular trafficking, tripartite synaptic localization, and polyadenylation of the astrocytic Fabp7 mRNA.
GeneRIF
Landry et al., Philadelphia, United States. In J Neurosci, 2012
An enrichment of Fabp7 mRNA and protein is confirmed in the astrocytic perisynaptic compartment and a diurnal change is observed as well in the intracellular distribution of Fabp7 mRNA in molecular layers of hippocampus.
[The clinical significance of fatty acid binding proteins].
Review
Chabowski et al., Laizhou, China. In Postepy Hig Med Dosw (online), 2010
The most important FABPs were isolated from the liver (L-FABP), heart (H-FABP), intestine (I-FABP), brain (B-FABP), epidermis (E-FABP) and adipocytes (A-FABP).
Brain lipid binding protein (FABP7) as modulator of astrocyte function.
Review
Beyer et al., Aachen, Germany. In Physiol Res, 2010
Recent findings from our lab suggest that brain lipid binding protein (FABP7) is implicated in the course of multiple sclerosis and the regulation of astrocyte function.
Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms.
Impact
Gutmann et al., Saint Louis, United States. In Cell Stem Cell, 2007
Using a newly developed brain lipid binding protein (BLBP)-Cre mouse strain to study the role of neurofibromin in neural progenitor cell function in the intact animal, we now show that neuroglial progenitor Nf1 inactivation results in increased glial lineage proliferation and abnormal neuronal differentiation in vivo.
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