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SLAM family member 8

BLAME, B lymphocyte activator macrophage expressed
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CD2, V1a, CD84, SLAM, CAN
Papers on BLAME
WHEN PARENTS WITH SEVERE MENTAL ILLNESS LOSE CONTACT WITH THEIR CHILDREN: ARE PSYCHIATRIC SYMPTOMS OR SUBSTANCE USE TO BLAME?
Fisher et al., Belmont, United States. In J Loss Trauma, 2008
This study compared parental psychiatric symptom severity, and the absence or presence of severe substance abuse, as predictors of contact with minor children for a representative sample of adults with diagnoses of serious mental illness (N = 45).
RELATION OF GUILT, SHAME, BEHAVIORAL AND CHARACTEROLOGICAL SELF-BLAME TO DEPRESSIVE SYMPTOMS IN ADOLESCENTS OVER TIME.
Ciesla et al., Kent, United States. In J Soc Clin Psychol, 2007
In a two-wave, longitudinal study, 221 nonreferred adolescents completed measures of guilt, shame, Behavioral self-blame (BSB), Characterological self-blame (CSB), depressive symptoms measures, and attributional style.
The role of self-blame for trauma as assessed by the Posttraumatic Cognitions Inventory (PTCI): a self-protective cognition?
Webster et al., Newcastle, Australia. In Behav Res Ther, 2007
The validity of the PTCI has received good support but doubts have been raised about its Self-BLAME subscale.
Gene expression profiles of U937 human macrophages exposed to Chlamydophila pneumoniae and/or low density lipoprotein in five study models using differential display and real-time RT-PCR.
Chow et al., Singapore, Singapore. In Biochimie, 2006
Other genes exhibiting altered expression include those that modulate inflammatory and immune responses or signal transduction linking infection to host immunity (ARPP-19, BLAME, HCA58, IK cytokine, IRS2, STAT1P1).
Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation.
van de Weerdt et al., Sydney, Australia. In J Immunol, 2003
Cell surface receptors belonging to the CD2 subset of the Ig superfamily of molecules include CD2, CD48, CD58, 2B4, signaling lymphocytic activation molecule (SLAM), Ly9, CD84, and the recently identified molecules NTB-A/Ly108/SLAM family (SF) 2000, CD84H-1/SF2001, B lymphocyte activator macrophage expressed (BLAME), and CRACC (CD2-like receptor-activating cytotoxic cells)/CS-1.
Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family.
Terhorst et al., Cambridge, United States. In Immunogenetics, 2002
The SLAM family of human genes currently consists of seven related members of the immunoglobulin superfamily, membrane-associated proteins, including CD150 (SLAM), CD244 (2B4), CD84, CD229 ( Ly-9), BLAME, CD48, and 19A.
Cloning, expression, and function of BLAME, a novel member of the CD2 family.
Villeval et al., Cambridge, United States. In J Immunol, 2001
Here we describe the cloning and expression analysis of a novel member of this family, B lymphocyte activator macrophage expressed (BLAME).
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