gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

WD repeat domain 46

predicted gene found in a dense cluster at the centromeric end of the major histocompatibility complex (MHC) on chromosome 20; gene product has no known function at this time [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: MHC, Daxx, HSET, KE2, INSL3
Papers on BING4
Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy.
Robbins et al., Bethesda, United States. In J Immunol, 2002
A lymphocyte clone recognized a previously unknown shared melanoma Ag that was identified as the BING-4 protein encoded in a gene-rich region of the extended class II MHC.
Physical mapping and evolution of the centromeric class I gene-containing region of the rat MHC.
Günther et al., Göttingen, Germany. In Immunogenetics, 2000
The following genes were identified and ordered as: (Syngap, Hset, Daxx, Bing1)-Tapbp-Rgl2-Ke2-Bing4-B3galt4- Rps18-Sacm2l-RT1-A1-RT1-A2-RT1-A3-Ring1-Ring2-++ +Ke4-Rxrb-Col11a2-RT1-Hb-Ring3-RT1-DMb.
Gene organisation, sequence variation and isochore structure at the centromeric boundary of the human MHC.
Beck et al., Cambridge, United Kingdom. In J Mol Biol, 1999
It includes two novel human genes (BING4 and SACM2L) and a thus far unnoticed human leucocyte antigen (HLA) class II pseudogene, termed HLA-DPA3.
TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.
Trowsdale et al., London, United Kingdom. In J Mol Biol, 1998
BING4 shows homologies only to hypothetical yeast and Caenorhabditis elegans proteins.
share on facebooktweetadd +1mail to friends