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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

BCL2-like 11

Top mentioned proteins: bcl-2, Bax, PrP, V1a, CAN
Papers using Bim antibodies
PCAF is an HIF-1[alpha] cofactor that regulates p53 transcriptional activity in hypoxia
Krstic-Demonacos Marija et al., In Molecular Cancer, 2007
... The following antibodies were used for western blotting and immunoprecipitation: Actin, Mcl-1 and Bim (Abcam), NOXA (Alexis), GR (2F8 ...
Necrotic death as a cell fate.
Wu Gen Sheng, In PLoS ONE, 2005
... Predesigned FOXO3a siRNA were purchased from Santa Cruz Biotechnology (Santa Cruz, CA), and Bim and control siRNA were from Qiagene (Valencia, CA).
Proteins released from degenerating neurons are surrogate markers for acute brain damage.
Di Giovanni Simone, In PLoS ONE, 2003
... antibodies and reagents were obtained from commercial sources: polyclonal rabbit anti-CDK1, cyclin B1, cyclin A, Bim, and c-Myb (Santa Cruz Biotechnology), mouse anti-CDK1 (Santa Cruz ...
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
Hunter Tony et al., In Breast Cancer Research : BCR, 2001
... (Santa Cruz, Santa Cruz, CA, USA), phosphorylated AKT (S473), cleaved caspase 3, Bim and Bim (IF specific) (Cell Signaling, Beverly, MA, USA), p27 ...
The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells.
Barry Michele, In PLoS Pathogens, 1999
... Bacterial expression plasmids for BimEL and vIRF-1 were generated by cloning of the respective coding sequences into pTYB4 (New England Biolabs; Ipswich, MA) and pGEX-4T-1 ...
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Papers on Bim
Overexpression of FOXO4 induces apoptosis of clear-cell renal carcinoma cells through downregulation of Bim.
Hu et al., Wuhan, China. In Mol Med Report, Feb 2016
Furthermore, the effects of vector‑mediated overexpression of FOXO4 on the apoptotic rate of the 786‑0 and Caki‑1 cell lines and the role of Bim in this process were investigated.
RANK-RANKL interactions are involved in cell adhesion-mediated drug resistance in multiple myeloma cell lines.
Nishida et al., Ōsaka, Japan. In Tumour Biol, Feb 2016
RANKL stimulation of RANK-expressing cells increased multidrug resistance protein 1 (MDR1), breast cancer resistance protein (BCRP), and lung resistance protein 1 (LRP1) expression and decreased Bim expression through various signaling molecules.
Nanostructured lipid carrier mediates effective delivery of methotrexate to induce apoptosis of rheumatoid arthritis via NF-κB and FOXO1.
Katare et al., Chandīgarh, India. In Int J Pharm, Feb 2016
The greater expression of pro-apoptotic gene Bim regulated by NF-κB-IkB and FOXO1 is supported by fold regulations calculated for various apoptotic and pro-inflammatory biomarkers carried out by RT-PCR.
A synthetic chalcone, 2'-hydroxy-2,3,5'-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells.
Shin et al., Seoul, South Korea. In Cancer Lett, Jan 2016
Further analysis revealed that DK143 produced reactive oxygen species (ROS) in MDA-MB-231 cells, but not in MCF10A cells, and upregulated the expression of ER stress sensors, including GRP78/BiP, IRE1α, CHOP, and Bim in MDA-MB-231 cells.
Cell death induced by endoplasmic reticulum stress.
Muñoz-Pinedo et al., l'Hospitalet de Llobregat, Spain. In Febs J, Dec 2015
These proteins aim to restore homeostasis, but they can also induce cell death, which has been shown to occur by necroptosis and, more commonly, through the regulation of Bcl-2 family proteins (Bim, Noxa and Puma) that leads to mitochondrial apoptosis.
An interconnected hierarchical model of cell death regulation by the BCL-2 family.
Cheng et al., Kettering, United States. In Nat Cell Biol, Oct 2015
Using combinatorial gain-of-function and loss-of-function approaches in Bid(-/-)Bim(-/-)Puma(-/-)Noxa(-/-) and Bax(-/-)Bak(-/-) cells, we have constructed an interconnected hierarchical model that accommodates and explains how the intricate interplays between the BCL-2 members dictate cellular survival versus death.
Regulation of Bim in Health and Disease.
Granot et al., Jerusalem, Israel. In Oncotarget, Oct 2015
The BH3-only Bim protein is a major determinant for initiating the intrinsic apoptotic pathway under both physiological and pathophysiological conditions.
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.
Kaufmann et al., Rochester, United States. In Biochim Biophys Acta, Jul 2015
Thirty years later we now understand that anti-apoptotic Bcl-2 family members modulate the intrinsic apoptotic pathway by binding and neutralizing the mitochondrial permeabilizers Bax and Bak as well as a variety of pro-apoptotic proteins, including the cellular stress sensors Bim, Bid, Puma, Bad, Bmf and Noxa.
Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches.
Yoshida et al., Kyoto, Japan. In Cell Stem Cell, Jul 2015
Several miRNA switches (miR-1-, miR-208a-, and miR-499a-5p-switches) efficiently purified cardiomyocytes differentiated from human PSCs, and switches encoding the apoptosis inducer Bim enriched for cardiomyocytes without cell sorting.
Cyclic AMP/PKA-promoted apoptosis: insights from studies of S49 lymphoma cells.
Zambon et al., San Diego, United States. In Horm Metab Res, 2014
Apoptosis in WT S49 cells occurs many hours after cAMP/PKA-promoted G1 cell cycle arrest and involves increased expression of Bim, a pro-apoptotic member of the Bcl-2 (B-cell lymphoma-2) family.
Melatonin as a proteasome inhibitor. Is there any clinical evidence?
Reiter et al., Winnipeg, Canada. In Life Sci, 2014
Proteasome inhibitors and melatonin are both intimately involved in the regulation of major signal transduction proteins including p53, cyclin p27, transcription factor NF-κB, apoptotic factors Bax and Bim, caspase 3, caspase 9, anti-apoptotic factor Bcl-2, TRAIL, NRF2 and transcription factor beta-catenin.
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.
Felsher et al., Stanford, United States. In Cancer Cell, 2014
Here we report that MYC via miR-17-92 maintains a neoplastic state through the suppression of chromatin regulatory genes Sin3b, Hbp1, Suv420h1, and Btg1, as well as the apoptosis regulator Bim.
Role of E2F-1 and its involving pathway in esophageal squamous cell carcinoma.
Chen et al., Beijing, China. In Thorac Cancer, 2014
Expression of E2F-1 and molecules involved in its targeted pathways, pERK, Bim, pRb, epidermal growth factor receptor, EZH2 and pAKT, was investigated immunohistochemically.
Paired immunoglobulin-like receptor A is an intrinsic, self-limiting suppressor of IL-5-induced eosinophil development.
Munitz et al., Tel Aviv-Yafo, Israel. In Nat Immunol, 2014
Upon self-recognition of β₂-microglobulin (β₂M) molecules, PIR-B served as a permissive checkpoint for IL-5-induced development of eosinophils by suppressing the proapoptotic activities of PIR-A, which were mediated by the Grb2-Erk-Bim pathway.
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Liston et al., Leuven, Belgium. In Nat Immunol, 2013
By contrast, excess Treg cells are removed by attrition, dependent on the Bim-initiated Bak- and Bax-dependent intrinsic apoptotic pathway.
BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals.
Letai et al., Boston, United States. In Cell Death Differ, 2008
Cloning and functional analysis of the bim gene.
More papers using Bim antibodies
BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway
Clark Edward A. et al., In The Journal of Experimental Medicine, 1999
... Rat anti-Bim (14A8) mAb was purchased from Kamiya Biomedical.
Biochemical and molecular investigations in respiratory chain deficiencies.
Aziz Syed A., In PLoS ONE, 1993
... The human Bak BH3 (CMGQVGRQLAIIGDDINRRYDS), mutated [L78A; D83A] Bak BH3 and Bim BH3 (CEIWIAQELRRIGDEFNAYYAR) peptides were purchased at Abgent (Interchim SA, Montluçon, France) ...
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