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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

BMP2 inducible kinase

Bike, BMP2K
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on Bike
A novel genetic variant of BMP2K contributes to high myopia.
GeneRIF
Tsai et al., Taiwan. In J Clin Lab Anal, 2008
BMP2K gene 1379 G/A variant is strongly correlated with high myopia and may contribute to a genetic risk factor for high degrees of myopic pathogenesis.
BMP-2 gene polymorphisms and osteoporosis: the Rotterdam Study.
GeneRIF
Uitterlinden et al., Rotterdam, Netherlands. In J Bone Miner Res, 2006
The association of the BMP-2 gene polymorphisms Ser37Ala and Arg190Ser with osteoporosis in 6353 men and women from the Rotterdam Study was studied.
Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells.
GeneRIF
Morita et al., Tokyo, Japan. In J Cell Physiol, 2004
PGE2 produced by COX-2 increased BMP-2 expression via binding the EP4 receptor.
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