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Acyl-CoA synthetase bubblegum family member 1

Bg1, BGI, very long-chain acyl-CoA synthetase
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on Bg1
Constitutive and inducible ER bodies of Arabidopsis thaliana accumulate distinct beta-glucosidases.
Nishimura et al., Okazaki, Japan. In Plant Cell Physiol, 2009
BGLU18, a member of the beta-glucosidase family in A. thaliana , is a component of inducible ER bodies in locally wounded cotyledons. [BGLU18]
Expression of an acyl-CoA synthetase, lipidosin, in astrocytes of the murine brain and its up-regulation during remyelination following cuprizone-induced demyelination.
Hashimoto et al., Machida, Japan. In J Neurosci Res, 2007
These data suggest that lipidosin was involved in fatty acid metabolism during reconstruction of the myelin sheath.
Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy.
Aubourg et al., Paris, France. In Hum Mol Genet, 2005
expression tends to be correlated with the severity of X-linked adrenoleukodystrophy
Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase.
Berger et al., Vienna, Austria. In Biochem J, 2004
Expression pattern and localization of bubblegum to microsomes.
The acyl-CoA synthetase "bubblegum" (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation..
Watkins et al., Baltimore, United States. In J Biol Chem, 2003
in neurons, mBG1-activated long-chain fatty acids are directed toward mitochondrial degradation
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