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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Brain expressed gene 1

Bex1, Bex2, Rex3
Top mentioned proteins: CAN, Bex, Rex-1, Histone, OUT
Papers on Bex1
The brain expressed x-linked gene 1 (Bex1) regulates myoblast fusion.
New
Kuang et al., West Lafayette, United States. In Dev Biol, Feb 2016
Here we identify brain expressed x-linked gene 1 (Bex1) as a transient, developmentally regulated gene involved in myoblast fusion.
Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats.
New
Takahashi et al., Nagoya, Japan. In Carcinogenesis, Dec 2015
Microarray analysis identified brain expressed, X-linked 1 (Bex1) as an upregulated gene in Cx32ΔTg rat liver.
Brain-Expressed X-linked (BEX) proteins in human cancers.
Review
New
Rönnstrand et al., Lund, Sweden. In Biochim Biophys Acta, Dec 2015
The Brain-Expressed X-linked (BEX) family proteins are comprised of five human proteins including BEX1, BEX2, BEX3, BEX4 and BEX5.
Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
New
Zhang et al., Beijing, China. In J Biol Chem, Nov 2015
Here we report that brain-expressed X-linked 2 (BEX2) is a novel downstream effector of mTOR.
BEX1 acts as a tumor suppressor in acute myeloid leukemia.
New
Kazi et al., Lund, Sweden. In Oncotarget, Sep 2015
In this report, we identified BEX1 as a novel regulator of oncogenic FLT3-ITD-driven AML.
The Plasmodium falciparum exportome contains non-canonical PEXEL/HT proteins.
New
Pick et al., Hamburg, Germany. In Mol Microbiol, Jul 2015
Furthermore, we show that non-canonical PEXEL/HTs can be cleaved and can promote export in both a REX3 and a GBP reporter, but not in a KAHRP reporter, indicating that non-canonical PEXEL/HTs are functional in concert with a supportive sequence environment.
Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer.
New
Ellis et al., Nottingham, United Kingdom. In Breast Cancer Res Treat, Apr 2015
In ER-positive tumours, GR was associated with other features of favourable outcome including FOXA1, GATA3 and BEX1 expression, while low GR expression was associated with high Ki67, p53 and CD71 expression.
Β-catenin is involved in Bex2 down-regulation induced glioma cell invasion/migration inhibition.
New
Yu et al., Xuzhou, China. In Biochem Biophys Res Commun, Feb 2015
Previously, we found that brain expressed X-linked gene 2 (Bex2) regulates the invasion/migration ability of glioma cells.
Genome-wide mRNA expression profiling in vastus lateralis of COPD patients with low and normal fat free mass index and healthy controls.
MacNee et al., Barcelona, Spain. In Respir Res, 2014
Five of these genes (CDKN1A, GADD45A, PMP22, BEX2, CGREF1, CYR61), were associated with cell cycle arrest and growth regulation and had been previously identified in studies relating muscle wasting and ageing.
Dynamics of Rex3 in the genomes of endangered Iberian Leuciscinae (Teleostei, Cyprinidae) and their natural hybrids.
Collares-Pereira et al., Lisbon, Portugal. In Mol Cytogenet, 2014
RESULTS: Partial Rex3 sequences evidenced high sequence homology among Leuciscinae (≥98 %) and different fish families (80-95 %) proposing a relatively recent activity of these elements in the species inspected.
Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma.
Korc et al., Indianapolis, United States. In Cell Death Dis, 2014
Gem also induced the expression of the antiapoptotic factors Nupr1, BEX2, and Bcl2a1, whereas ISRIB reduced their expression.
Organization and Chromosomal Distribution of Histone Genes and Transposable Rex Elements in the Genome of Astyanax bockmanni (Teleostei, Characiformes).
Porto-Foresti et al., Bauru, Brazil. In Cytogenet Genome Res, 2014
Probes for the transposable elements Rex1 and Rex6 showed small sites dispersed on most chromosomes of the 6 populations, and the Rex3 element is located in a big block concentrated in only 1 acrocentric chromosome of 2 populations.
Mapping of the Retrotransposable Elements Rex1 and Rex3 in Chromosomes of Eigenmannia (Teleostei, Gymnotiformes, Sternopygidae).
Foresti et al., Botucatu, Brazil. In Cytogenet Genome Res, 2014
This study identified the retrotransposable elements Rex1 and Rex3 in the genomes of 6 cytotypes of Eigenmannia.
Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs.
Vilar et al., Madrid, Spain. In Plos One, 2014
The family of Brain Expressed and X-linked (Bex) proteins consists of 5 members in humans (Bex1-5).
Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU.
GeneRIF
Song et al., Taejŏn, South Korea. In Korean J Parasitol, 2012
Expression of ALDH1A2, BEX2, EGR2, CCL3 and PLAU are upregulated in Toxoplasma gondiisusceptible C57BL/6 mice.
Bex1 is involved in the regeneration of axons after injury.
GeneRIF
Young et al., Münster, Germany. In J Neurochem, 2010
Bex1 protein is over-expressed as a result of peripheral axonal damage and antagonizes the axon outgrowth inhibitory effect of myelin-associated glycoprotein.
Inhibition of apoptosis by downregulation of hBex1, a novel mechanism, contributes to the chemoresistance of Bcr/Abl+ leukemic cells.
GeneRIF
Zhu et al., Hangzhou, China. In Carcinogenesis, 2009
expression of hBex1 in leukemic cells is a novel mechanism by which chemoresistance is achieved and suggests that hBex1 is a potential molecular target for the development of novel leukemia treatments
Bex1 knock out mice show altered skeletal muscle regeneration.
GeneRIF
Margolis et al., Baltimore, United States. In Biochem Biophys Res Commun, 2007
Thus, our results provide the first evidence that Bex1-KO mice show altered muscle regeneration, and allow us to propose that the interaction of Bex1 with Ca(2+)/CaM may be involved in skeletal muscle regeneration.
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.
GeneRIF
Madan et al., Iowa City, United States. In Cancer Res, 2006
Two novel brain expressed genes, BEX1 and BEX2 are identified; they are silenced in all glioma specimens and exhibit extensive promoter hypermethylation.
Nerve growth factor-dependent regulation of NADE-induced apoptosis.
Review
Sato et al., New York City, United States. In Vitam Horm, 2002
NADE has at least four isoforms, designated as NADE2, NADE3, NADE4/Bex1, and NADE5/Bex2.
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