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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Neurogenic differentiation 1

beta2
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on beta2
NeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.
GeneRIF
Klein et al., Bethesda, United States. In J Neurochem, 2012
This study suggested that NeuroD1 may act through Aipl1 and other genes to maintain photoreceptor homeostasis
Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.
GeneRIF
Philpott et al., Cambridge, United Kingdom. In Development, 2012
NeuroD promoter is substantially more sensitive to the phosphorylation status of Ngn2 than the Delta promoter, and that this can be attributed to differences in the ease of promoter activation.
NeuroD1 is an upstream regulator of NSCL1.
GeneRIF
Kim, United States. In Biochem Biophys Res Commun, 2012
These results demonstrate that NeuroD1 is an upstream regulator of the NSCL1 gene but not the NSCL2 gene in mice.
Derivation of human differential photoreceptor-like cells from the iris by defined combinations of CRX, RX and NEUROD.
GeneRIF
Umezawa et al., Japan. In Plos One, 2011
Photosensitive photoreceptor cells can be generated by combinations of transcription factors. The combination of CRX and RX generate immature photoreceptors: and additional NEUROD promotes maturation.
Combined transfection of the three transcriptional factors, PDX-1, NeuroD1, and MafA, causes differentiation of bone marrow mesenchymal stem cells into insulin-producing cells.
GeneRIF
Huang et al., Nantong, China. In Exp Diabetes Res, 2011
Combined transfection of the three transcriptional factors, PDX-1, NeuroD1, and MafA, causes differentiation of bone marrow mesenchymal stem cells into insulin-producing cells
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