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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 10 Aug 2015.

Beta-2-microglobulin

beta2-microglobulin
Top mentioned proteins: beta2, HAD, CAN, AGE, Serum albumin
Papers on beta2-microglobulin
Prognostic significance of increased bone marrow microcirculation in newly diagnosed multiple myeloma: results of a prospective DCE-MRI study.
New
Hillengass et al., Heidelberg, Germany. In Eur Radiol, 29 Aug 2015
RESULTS: Correlation analysis revealed significant positive association between beta2-microglobulin as well as immunoparesis with DCE-MRI parameters A and k ep.
HLA class I depleted hESC as a source of hypoimmunogenic cells for tissue engineering applications.
New
Sarvazyan et al., Washington, D.C., United States. In Tissue Eng Part A, 28 Aug 2015
METHODS AND RESULTS: Beta2-microglobulin expression was decreased by lentiviral transduction using human anti HLA class I light chain beta2-microglobulin (B2M) shRNA.
Clinical Features and Survival of 338 Multiple Myeloma Patients Treated with Hematopoietic Stem Cell Transplantation or Conventional Chemotherapy.
New
Ramirez et al., Murcia, Spain. In Eur J Haematol, 17 Aug 2015
The presence of bone lesions (72.2%), as well as anemia (79.8%) and elevated beta2-microglobulin levels (62.3%) was a common finding; in contrast, hypercalcemia and elevated serum creatinine were less frequent (25% each).
Usefulness of Beta2-Microglobulin as a Predictor of All-Cause and Nonculprit Lesion-Related Cardiovascular Events in Acute Coronary Syndromes (from the PROSPECT Study).
New
Stone et al., Berlin, Germany. In Am J Cardiol, 16 Aug 2015
Beta2-microglobulin displayed the strongest predictive power of all variables assessed for all-cause and nonculprit lesion-related MACE.
Dysregulation of the NLRP3 inflammasome complex and related cytokines in patients with multiple myeloma.
New
Li et al., In Hematology, 06 Aug 2015
We further demonstrated that NLRP3 mRNA was negatively correlated with beta2-microglobulin and plasma cell percentage in MM.
Role of β2-microglobulin in uremic patients may be greater than originally suspected.
Review
New
Zumrutdal, Adana, Turkey. In World J Nephrol, Mar 2015
The role of beta2-microglobulin (β2M) in dialysis-related amyloidosis as a specific amyloid precursor was defined in the 1980s.
Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.
Review
New
Kang et al., Seoul, South Korea. In World J Gastroenterol, May 2014
Here, we have reviewed and discussed the molecular and prognostic features of MSI-H CRCs, as well as several putative prognostic or predictive molecular markers, including HSP110 expression, beta2-microglobulin mutations, myosin 1a expression, CDX2/CK20 expression, SMAD4 expression, CIMP status and LINE-1 methylation levels.
[Pathogenesis of microsatellite-unstable colorectal cancer. Evaluation of new diagnostic and therapeutic options].
Review
Kloor, Heidelberg, Germany. In Pathologe, 2013
A further characteristic feature of MSI-H cancers is the occurrence of alterations affecting the cellular antigen presentation mechanism where beta2-microglobulin (B2M) mutations that directly result from DNA mismatch repair deficiency represent the most common mechanism.
Predictors for the development of non-Hodgkin lymphoma in primary Sjögren's syndrome.
Review
Jonsson et al., Bergen, Norway. In Presse Med, 2012
Among the established predictors for lymphoma development in SS, we recognize recurrent or permanent swelling of major salivary glands (SG), lymphadenopathy, cryoglobulinemia, splenomegaly, low complement levels of C4 and C3, lymphopenia, skin vasculitis or palpable purpura, M-component in serum or urine, peripheral neuropathy, glomerulonephritis and elevated beta2-microglobulin.
Osteo-articular manifestations of amyloidosis.
Review
Grateau et al., Paris, France. In Best Pract Res Clin Rheumatol, 2012
The amyloidosis responsible for osteo-articular manifestations are the AL immunoglobulin amyloidosis, the beta2-microglobulin amyloidosis in patients under haemodialysis and finally the amyloidosis of transthyretin (genetic and senile).
Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury.
Impact
Maurer et al., Basel, Switzerland. In Nat Biotechnol, 2010
Whereas urinary clusterin outperformed BUN and SCr for detecting proximal tubular injury, urinary total protein, cystatin C and beta2-microglobulin showed a better diagnostic performance than BUN and SCr for detecting glomerular injury.
Follicular lymphoma international prognostic index 2: a new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor project.
Impact
Solal-Céligny et al., Modena, Italy. In J Clin Oncol, 2009
beta2-microglobulin higher than the upper limit of normal, longest diameter of the largest involved node longer than 6 cm, bone marrow involvement, hemoglobin level lower than 12 g/dL, and age older than 60 years were factors independently predictive for PFS.
Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.
Impact
Montserrat et al., Barcelona, Spain. In J Clin Oncol, 2009
Advanced clinical stage, del(17p), or increased serum beta2-microglobulin levels correlated with a lower CR rate.
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group.
Impact
German Chronic Lymphocytic Leukemia Study Group et al., Ulm, Germany. In J Clin Oncol, 2009
Efficacy did not vary significantly in subgroups defined by genetic parameters (in particular, in 17p deletion, 11q deletion, mutated TP53, and unmutated VH), but efficacy was inferior in patients with increased beta2-microglobulin (beta2-MG) and thymidine kinase (TK).
Identification of leptomeningeal disease in aggressive B-cell non-Hodgkin's lymphoma: improved sensitivity of flow cytometry.
Impact
Spanish Group for the Study of CNS Disease in NHL et al., Salamanca, Spain. In J Clin Oncol, 2009
Interestingly, in Burkitt lymphoma, presence of CNS disease by FCM could be predicted with a high specificity when increased serum beta2-microglobulin and neurological symptoms coexisted, while peripheral blood involvement was the only independent parameter associated with CNS disease in diffuse large B-cell lymphoma, with low predictive value.
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