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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 24 Oct 2014.

Beta-2-microglobulin

beta2-microglobulin
Top mentioned proteins: beta2, HAD, CAN, AGE, Serum albumin
Papers on beta2-microglobulin
Serum free light chains of immunoglobulins as biomarkers for systemic sclerosis characteristics, activity and severity.
Review
New
Dubucquoi et al., Lille, France. In Autoimmun Rev, Aug 2014
In multivariate analysis, beta2-microglobulin levels correlated with disease activity, BAFF levels with severity and sFLC with neither of these.
Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.
New
Kang et al., Seoul, South Korea. In World J Gastroenterol, May 2014
Here, we have reviewed and discussed the molecular and prognostic features of MSI-H CRCs, as well as several putative prognostic or predictive molecular markers, including HSP110 expression, beta2-microglobulin mutations, myosin 1a expression, CDX2/CK20 expression, SMAD4 expression, CIMP status and LINE-1 methylation levels.
Proteomic studies in endemic nephropathy.
New
Dihazi et al., Niš, Serbia. In Prilozi, Dec 2013
Urine beta2-microglobulin (B2M) was mainly used as a tubular marker of EN but recently alpha1-microglobulin (AMBP) was proposed for the diagnosis of EN.
[Hypercoagulability in multiple myeloma].
New
In Ter Arkh, Dec 2013
The level of D-dimer was statistically significantly positively correlated with the endogenous thrombin potential and the amount of beta2-microglobulin.
[Clinical value of the determination of markers for endothelial dysfunction (endothelin-1, microalbuminuria) and tubulointerstitial tissue lesion (β2-microglobulin, monocyte chemotactic protein-1) in hypertensive patients with uric acid metabolic disorders].
New
Balkarov et al., In Ter Arkh, Dec 2013
AIM: To identify the risk factors of kidney injuries in hypertensive patients with uric acid (UA) metabolic disorders in order to choose the optimal management tactics, by analyzing the changes in markers for endothelial dysfunction (endothelin-1 (ET-1), microalbuminuria (MAU), intima-media thickness (IMT)) and tubulointerstitial tissue lesion (beta2-microglobulin (beta2-MG, monocyte chemotactic protein-1 (MCP-1)).
Beta2-microglobulin as a diagnostic marker in cerebrospinal fluid: a follow-up study.
New
Lánská et al., Kralupy nad Vltavou, Czech Republic. In Dis Markers, Dec 2013
Beta2-Microglobulin ( β 2-m) is a low molecular weight protein occurring in all body fluids.
Predictors for the development of non-Hodgkin lymphoma in primary Sjögren's syndrome.
Review
Jonsson et al., Bergen, Norway. In Presse Med, 2012
Among the established predictors for lymphoma development in SS, we recognize recurrent or permanent swelling of major salivary glands (SG), lymphadenopathy, cryoglobulinemia, splenomegaly, low complement levels of C4 and C3, lymphopenia, skin vasculitis or palpable purpura, M-component in serum or urine, peripheral neuropathy, glomerulonephritis and elevated beta2-microglobulin.
Osteo-articular manifestations of amyloidosis.
Review
Grateau et al., Paris, France. In Best Pract Res Clin Rheumatol, 2012
The amyloidosis responsible for osteo-articular manifestations are the AL immunoglobulin amyloidosis, the beta2-microglobulin amyloidosis in patients under haemodialysis and finally the amyloidosis of transthyretin (genetic and senile).
Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury.
Impact
Maurer et al., Basel, Switzerland. In Nat Biotechnol, 2010
Whereas urinary clusterin outperformed BUN and SCr for detecting proximal tubular injury, urinary total protein, cystatin C and beta2-microglobulin showed a better diagnostic performance than BUN and SCr for detecting glomerular injury.
Moving from prognostic to predictive factors in chronic lymphocytic leukaemia (CLL).
Review
Stilgenbauer et al., Ulm, Germany. In Best Pract Res Clin Haematol, 2010
In addition, serum markers (e.g., thymidine kinase (TK) and beta2-microglobulin (beta2-MG)), cellular markers (e.g., CD38 and ZAP70) and clinical staging have an impact on outcome in CLL.
[Screening for subclinical complications in children and adolescents with type 1 diabetes: experience acquired in Brussels].
Review
Dorchy, Brussels, Belgium. In Rev Med Brux, 2009
Early microproteinuria is of mixed origin, being both glomerular (microalbumin) and tubular (beta2-microglobulin).
Follicular lymphoma international prognostic index 2: a new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor project.
Impact
Solal-Céligny et al., Modena, Italy. In J Clin Oncol, 2009
beta2-microglobulin higher than the upper limit of normal, longest diameter of the largest involved node longer than 6 cm, bone marrow involvement, hemoglobin level lower than 12 g/dL, and age older than 60 years were factors independently predictive for PFS.
Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.
Impact
Montserrat et al., Barcelona, Spain. In J Clin Oncol, 2009
Advanced clinical stage, del(17p), or increased serum beta2-microglobulin levels correlated with a lower CR rate.
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group.
Impact
German Chronic Lymphocytic Leukemia Study Group et al., Ulm, Germany. In J Clin Oncol, 2009
Efficacy did not vary significantly in subgroups defined by genetic parameters (in particular, in 17p deletion, 11q deletion, mutated TP53, and unmutated VH), but efficacy was inferior in patients with increased beta2-microglobulin (beta2-MG) and thymidine kinase (TK).
Identification of leptomeningeal disease in aggressive B-cell non-Hodgkin's lymphoma: improved sensitivity of flow cytometry.
Impact
Spanish Group for the Study of CNS Disease in NHL et al., Salamanca, Spain. In J Clin Oncol, 2009
Interestingly, in Burkitt lymphoma, presence of CNS disease by FCM could be predicted with a high specificity when increased serum beta2-microglobulin and neurological symptoms coexisted, while peripheral blood involvement was the only independent parameter associated with CNS disease in diffuse large B-cell lymphoma, with low predictive value.
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