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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Beta-2-microglobulin

beta2-microglobulin
Top mentioned proteins: beta2, HAD, CAN, AGE, Serum albumin
Papers on beta2-microglobulin
Clinicopathologic features and outcomes of lymphoplasmacytic lymphoma patients with monoclonal IgG or IgA paraprotein expression.
New
Young et al., Houston, United States. In Leuk Lymphoma, Jan 2016
The IgA-LPL group was more likely to present with B symptoms, a high beta2-microglobulin level and extramedullary involvement.
Life expectancy of young adults with follicular lymphoma.
New
Zucca et al., Biella, Italy. In Ann Oncol, Nov 2015
RESULTS: Patients younger than 40 had a lower incidence of elevated LDH, high beta2-microglobulin, and a high-risk Follicular Lymphoma International Prognostic Index (FLIPI) score, whereas bone marrow involvement and bulky and disseminated lymphadenopathy were more frequent.
Usefulness of Beta2-Microglobulin as a Predictor of All-Cause and Nonculprit Lesion-Related Cardiovascular Events in Acute Coronary Syndromes (from the PROSPECT Study).
New
Stone et al., Berlin, Germany. In Am J Cardiol, Nov 2015
Beta2-microglobulin displayed the strongest predictive power of all variables assessed for all-cause and nonculprit lesion-related MACE.
Role of β2-microglobulin in uremic patients may be greater than originally suspected.
Review
New
Zumrutdal, Adana, Turkey. In World J Nephrol, Mar 2015
The role of beta2-microglobulin (β2M) in dialysis-related amyloidosis as a specific amyloid precursor was defined in the 1980s.
Extranodal diffuse large B-cell lymphoma with monoclonal gammopathy: an aggressive and primary refractory disease responding to an immunomodulatory agent.
Mian et al., Messina, Italy. In Exp Hematol Oncol, 2014
CASE PRESENTATION: The 73-year-old male patient presented with lateral cervical lymphadenopathy, B symptoms, lactate dehydrogenase and beta2-microglobulin elevation.
A covalent homodimer probing early oligomers along amyloid aggregation.
Ricagno et al., Milano, Italy. In Sci Rep, 2014
We focused on the amyloidogenic protein beta2-microglobulin (β2m) whose early oligomers are still a matter of debate.
Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.
Review
Kang et al., Seoul, South Korea. In World J Gastroenterol, 2014
Here, we have reviewed and discussed the molecular and prognostic features of MSI-H CRCs, as well as several putative prognostic or predictive molecular markers, including HSP110 expression, beta2-microglobulin mutations, myosin 1a expression, CDX2/CK20 expression, SMAD4 expression, CIMP status and LINE-1 methylation levels.
Proteomic studies in endemic nephropathy.
Review
Dihazi et al., Niš, Serbia. In Prilozi, 2013
Urine beta2-microglobulin (B2M) was mainly used as a tubular marker of EN but recently alpha1-microglobulin (AMBP) was proposed for the diagnosis of EN.
[Pathogenesis of microsatellite-unstable colorectal cancer. Evaluation of new diagnostic and therapeutic options].
Review
Kloor, Heidelberg, Germany. In Pathologe, 2013
A further characteristic feature of MSI-H cancers is the occurrence of alterations affecting the cellular antigen presentation mechanism where beta2-microglobulin (B2M) mutations that directly result from DNA mismatch repair deficiency represent the most common mechanism.
Osteo-articular manifestations of amyloidosis.
Review
Grateau et al., Paris, France. In Best Pract Res Clin Rheumatol, 2012
The amyloidosis responsible for osteo-articular manifestations are the AL immunoglobulin amyloidosis, the beta2-microglobulin amyloidosis in patients under haemodialysis and finally the amyloidosis of transthyretin (genetic and senile).
Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury.
Impact
Maurer et al., Basel, Switzerland. In Nat Biotechnol, 2010
Whereas urinary clusterin outperformed BUN and SCr for detecting proximal tubular injury, urinary total protein, cystatin C and beta2-microglobulin showed a better diagnostic performance than BUN and SCr for detecting glomerular injury.
Follicular lymphoma international prognostic index 2: a new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor project.
Impact
Solal-Céligny et al., Modena, Italy. In J Clin Oncol, 2009
beta2-microglobulin higher than the upper limit of normal, longest diameter of the largest involved node longer than 6 cm, bone marrow involvement, hemoglobin level lower than 12 g/dL, and age older than 60 years were factors independently predictive for PFS.
Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.
Impact
Montserrat et al., Barcelona, Spain. In J Clin Oncol, 2009
Advanced clinical stage, del(17p), or increased serum beta2-microglobulin levels correlated with a lower CR rate.
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group.
Impact
German Chronic Lymphocytic Leukemia Study Group et al., Ulm, Germany. In J Clin Oncol, 2009
Efficacy did not vary significantly in subgroups defined by genetic parameters (in particular, in 17p deletion, 11q deletion, mutated TP53, and unmutated VH), but efficacy was inferior in patients with increased beta2-microglobulin (beta2-MG) and thymidine kinase (TK).
Identification of leptomeningeal disease in aggressive B-cell non-Hodgkin's lymphoma: improved sensitivity of flow cytometry.
Impact
Spanish Group for the Study of CNS Disease in NHL et al., Salamanca, Spain. In J Clin Oncol, 2009
Interestingly, in Burkitt lymphoma, presence of CNS disease by FCM could be predicted with a high specificity when increased serum beta2-microglobulin and neurological symptoms coexisted, while peripheral blood involvement was the only independent parameter associated with CNS disease in diffuse large B-cell lymphoma, with low predictive value.
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