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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Apolipoprotein H

beta2-glycoprotein I, apolipoprotein H, beta(2)GPI, APOH
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CD45, beta2, Aps, HAD, IgM
Papers on beta2-glycoprotein I
APOH interacts with FTO to predispose to healthy thinness.
Hunt et al., Salt Lake City, United States. In Hum Genet, Feb 2016
Significance was obtained for the interaction of FTO rs9939609 with APOH missense variant rs52797880 (minor allele frequency 0.054).
Targeted Proteomics Identifies PON1 and Apolipoprotein Cs as Potential Risk Factors for Hypoalphalipoproteinemia in Diabetic Subjects Treated with Fenofibrate and Rosiglitazone.
Heinecke et al., Washington, D.C., United States. In Mol Cell Proteomics, Jan 2016
This approach demonstrated marked increases in the relative concentrations of paraoxonase/arylesterase 1 (PON1), apolipoprotein C-II (APOC2), apolipoprotein C-I, and apolipoprotein H in the HDL of subjects who developed hypoalphalipoproteinemia.
Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the kidneys.
Yamanishi et al., Hirakata, Japan. In Int J Mol Med, Sep 2015
Similar analyses of SHRSP-specific genes revealed that angiotensinogen (Agt), angiotensin II receptor-associated protein (Agtrap) and apolipoprotein H (Apoh) were possible candidate genes responsible for triggering strokes.
Lipopolysaccharide Enhances Beta2-Glycoprotein I Activation of Nuclear Factor κB in Liver Cancer Cells.
Zhang et al., In Clin Lab, 2014
BACKGROUND: Beta2-glycoprotein I (β2GPI) is a highly abundant glycoprotein in plasma.
Interactions between Hepatitis C Virus and the Human Apolipoprotein H Acute Phase Protein: A Tool for a Sensitive Detection of the Virus.
Veas et al., Montpellier, France. In Plos One, 2014
Based upon previous studies on HBV, we worked on the capacity of the scavenger acute phase protein, Apolipoprotein H (ApoH) to interact with HCV.
Association of the Trp316Ser variant (rs1801690) near the apolipoprotein H (β2-glycoprotein-I) gene and serum lipid levels.
Yang et al., Nanning, China. In Int J Clin Exp Pathol, 2014
The objective of the present study was to detect the association of the Trp316Ser variant (rs1801690) near the apolipoprotein H (β2-glycoprotein-I) gene and serum lipid levels in the Mulao and Han populations.
Reduced beta 2 glycoprotein I improve diabetic nephropathy via inhibiting TGF-β1-p38 MAPK pathway.
Yu et al., Tianjin, China. In Int J Clin Exp Med, 2014
PURPOSE: Beta 2 glycoprotein I (β2GPI) has been shown the positive effect on diabetic atherosclerosis and retinal neovascularization.
The composition and metabolism of large and small LDL.
Schaefer et al., Boston, United States. In Curr Opin Lipidol, 2014
Proteins associated with LDL, in addition to apolipoprotein (apo) B, include the C apolipoproteins, apoA-I, apoA-IV, apoD, apoE, apoF, apoH, apoJ, apoL-1, apoM, α-1 antitrypsin, migration inhibitory factor-related protein 8, lysosome C, prenylcysteine oxidase 1, paraoxonase 1, transthyretin, serum amyloid A4, and fibrinogen α chain.
Tomography and blood vessels in Hughes syndrome.
Djokovic et al., Belgrade, Serbia. In Lupus, 2014
Antiphospholipid antibody syndrome (APS) or Hughes syndrome is a multisystem autoimmune disorder that is characterized by venous and arterial thrombosis and/or pregnancy complications (miscarriage and fetal death, preeclampsia, placental insufficiency, and fetal growth restriction), and positive serologic tests for anticardiolipin antibodies (aCL), lupus anticoagulant (LA), or antibodies against beta2-glycoprotein I (anti-ß₂GPI) either of IgG or IgM isotype.
Antiphospholipid antibodies and cerebellar ataxia: a clinical analysis and literature review.
Yin et al., Kao-hsiung, Taiwan. In Neuroimmunomodulation, 2013
The predominant APAbs for subacute and chronic ataxia were the anti-beta2-glycoprotein I antibody and anticardiolipin antibody, respectively.
From antibody to clinical phenotype, the black box of the antiphospholipid syndrome: pathogenic mechanisms of the antiphospholipid syndrome.
de Laat et al., Utrecht, Netherlands. In Thromb Res, 2013
In an attempt to get insight in what takes place inside the black box, we have analyzed 126 mechanistical studies on aPLs and discussed differences in the type of antibodies that were used, the involvement of beta2-glycoprotein I (β2GPI), and the criteria used to diagnose APS patients.
Antiphospholipid antibodies: evaluation of the thrombotic risk.
Devreese, Gent, Belgium. In Thromb Res, 2012
The laboratory diagnosis of the antiphospholipid syndrome (APS) via antiphospholipid antibody (aPL) tests, including lupus anticoagulant (LAC), anti-cardiolipin (aCL), or anti-beta2 glycoprotein I (aβ2GPI) antibodies remains a challenge.
Val247Leu β2-glycoprotein-I allelic variant is associated with antiphospholipid syndrome: systematic review and meta-analysis.
Espinosa et al., Barcelona, Spain. In Autoimmun Rev, 2012
[review] Val/Val genotype of beta2-GPI gene is associated with antiphospholipid syndrome (APS), by patients with APS, with production of anti-beta2-GPI antibodies.
OS045. Multi-dimensional protein identification technology analysis of syncytiotrophoblast vesicles released from perfused preeclampsia placentas.
Redman et al., Oxford, United Kingdom. In Pregnancy Hypertens, 2012
Our analysis also reveals that proteins known to be elevated in blood before, or at, the time of pre-eclampsia are elevated or unique in STBM from PE placentas, including Fetuin A, Inter-alpha (globulin) inhibitor H4, Serum amyloid P component, Apolipoprotein H (or B2GP1) and Apolipoprotein AII.
Recent developments in our understanding of the antiphospholipid syndrome.
Urbanus et al., Utrecht, Netherlands. In Int J Lab Hematol, 2012
Recent developments in our understanding of the antiphospholipid syndrome. (review)
Antibodies against domain I of β2-glycoprotein I: the one and only?
de Laat et al., Maastricht, Netherlands. In Lupus, 2012
epitope glycine40-arginine43 of domain I of beta2GPI predominantly responsible for binding thrombosis related antibodies [review]
Circulating β2 glycoprotein I-IgG anti-β2 glycoprotein I immunocomplexes in patients with definite antiphospholipid syndrome.
Pengo et al., Padova, Italy. In Lupus, 2012
immunocomplexes of Hep, beta2GPI and anti-beta2GPI IgG in plasma of patients with antiphospholipid syndrome
Anti-beta2-glycoprotein I antibody and cerebellar ataxia in breast cancer.
Chen et al., In Lupus, 2012
Letter: report breast cancer patient with elevated anti-beta2-glycoprotein I antibody and cerebellar ataxia.
Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor.
Bevers et al., Bergamo, Italy. In Lancet, 1990
aca-cofactor is a single chain polypeptide with an apparent molecular weight of 50 kD (non-reduced), which increases to 70 kD upon reduction, and its properties closely resemble those of beta 2-glycoprotein I (apolipoprotein H).
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