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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 02 Oct 2014.

Actin, beta

beta-actin
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Actin, CAN, POLYMERASE, HAD, GAPDH
Papers using beta-actin antibodies
Drosophila Sex lethal gene initiates female development in germline progenitors.
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Cooney Austin John, In PLoS ONE, 2010
... cells (PAGCs) cocultured experiments, transgenic mice carrying the Enhanced Green Fluorescent Protein driven by chicken beta-actin promoter and CMV intermediate early enhancer (EGFP transgenic mice ...
Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination.
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Lustig Arthur J., In PLoS ONE, 2010
... Beta-actin antibody was from Abcam (catalog # ab8224) ...
Accumulation of p53 and reductions in XIAP abundance promote the apoptosis of prostate cancer cells
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Mohapatra Subhra et al., In Molecular Cancer, 2004
... The beta-actin antibody was obtained from Sigma, the PARP antibody from Santa Cruz Biotechnology, and the MIF antibody ...
Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities.
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Brown Earl G., In PLoS ONE, 2003
... Anti-myc antibody (Cell Signaling, Danvers, MA, USA), anti-beta-actin antibody (GenScript, Piscataway, NJ, USA) were ...
Techniques in protein methylation
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Asahara Hiroshi et al., In BMC Developmental Biology, 2003
... A) Human CARM1 cDNA under control of the cytomegalovirus immediate early enhancer-chicken beta-actin hybrid promoter (pCAGGS expression vector) was used to generate a transgenic line by male pronuclei ...
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Papers on beta-actin
Wnt signaling cascade in restenosis: a potential therapeutic target of public health relevance in a North American cohort of Nebraska State.
New
Chandravati et al., Lucknow, India. In Mol Biol Rep, Jul 2014
Wnt2 and Wnt5a mRNA transcripts were expressed in human VSMCs; however, Wnt1, Wnt4 and Wnt11 mRNA were not expressed; beta-actin was used as an internal control.
Structure of cortical cytoskeleton in fibers of mouse muscle cells after being exposed to a 30-day space flight on board the BION-M1 biosatellite.
New
Larina et al., Moscow, Russia. In J Appl Physiol, Jun 2014
At the same time, the content of beta-actin in the cytoplasmic fraction of proteins was found to be decreased in all types of studied tissues compared with the control levels in the postflight group, with lowered beta-actin gene expression rates in the postflight group.
Phospho-NHE3 forms membrane patches and interacts with beta-actin to sense and maintain constant direction during cell migration.
New
Funk et al., Dresden, Germany. In Exp Cell Res, Jun 2014
The Na(+)/H(+) exchanger NHE3 colocalizes with beta-actin at the leading edge of directionally migrating cells.
Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury.
New
Mandell et al., Charlottesville, United States. In Acta Neuropathol Commun, Dec 2013
Because Wallerian degeneration is well known to involve cytoskeletal disassembly and because caspases are recently implicated in aspects of this process, we asked whether antibodies directed at caspase-generated neoepitopes of beta-actin and alpha-tubulin would be useful immunohistochemical markers of pathological and developmental axon degeneration.
Beta-actin deficiency with oxidative posttranslational modifications in Rett syndrome erythrocytes: insights into an altered cytoskeletal organization.
New
Hayek et al., Siena, Italy. In Plos One, Dec 2013
Our findings demonstrate, for the first time, a beta-actin down-regulation and oxidative PTMs for RBCs of RTT patients, thus indicating an altered cytoskeletal organization.
Reference genes for measuring mRNA expression.
Review
Ling et al., Thāne, India. In Theory Biosci, 2012
These genes, such as GADPH and beta-actin, are used extensively for gene expression studies using techniques like quantitative PCR.
β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration.
GeneRIF
Singer et al., New York City, United States. In Genes Dev, 2012
the zipcode-binding protein 1 transports beta-actin mRNA to the focal adhesion compartment, it dwells for minutes, associating its localization with motility through the formation of stable connections between adhesions and newly synthesized actin filaments
[Acute and chronic stress induced changes in gene transcriptions related to Alzheimer's disease].
GeneRIF
Kálmán et al., Szeged, Hungary. In Ideggyogy Sz, 2012
Findings demonstrate that both acute and chronic Immobilization Stress lead to gene transcriptional changes of beta-actin, APP and MAPK-1. These changes may lead to cognitive deterioration, and the development of Alzheimer disease.
De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.
Impact
GeneRIF
Dobyns et al., Seattle, United States. In Nat Genet, 2012
identified de novo missense changes in the cytoplasmic actin-encoding genes ACTB and ACTG1 in one and two probands, respectively; suggest that Baraitser-Winter syndrome is the predominant phenotype associated with mutation of these two genes
Active maintenance of nuclear actin by importin 9 supports transcription.
GeneRIF
Vartiainen et al., Helsinki, Finland. In Proc Natl Acad Sci U S A, 2012
Recombinant human actin is constantly shuttled into the murine nucleus by importin 9 and out by exportin 6. Nuclear actin is required for maximal transcription.
Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.
GeneRIF
Ervasti et al., Minneapolis, United States. In Plos One, 2011
novel roles for beta-actin in promoting complex CNS tissue architecture
[Application of nucleic acids and proteins in estimation of postmortem interval].
Review
Chen et al., Shanghai, China. In Fa Yi Xue Za Zhi, 2011
The housekeeping gene mRNA, for example beta-actin, GAPDH, has certain stability and can be used to PMI estimation as internal standard.
[Differentiation of functional cells from iPS cells by efficient gene transfer].
Review
Mizuguchi et al., Ōsaka, Japan. In Yakugaku Zasshi, 2010
By using an adenovirus (Ad) vector containing the cytomegalovirus enhancer/beta-actin (CA) promoters, we have developed an efficient transduction system for mouse mesenchymal stem cells and embryonic stem (ES) cells.
Improved applications of the tetracycline-regulated gene depletion system.
Review
Shibahara et al., Mishima, Japan. In Biosci Trends, 2009
We also employed a CMV immediate early enhancer/beta-actin (CAG) promoter to express a Tet-controlled transactivator.
Gene therapy and transplantation in the retinofugal pathway.
Review
Rodger et al., Australia. In Prog Brain Res, 2008
Strong, constitutive promoters such as CMV and/or beta-actin are commonly used but cell-specific promoters have also been tested.
Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival.
Impact
Jaffrey et al., New York City, United States. In Nat Cell Biol, 2008
During development of the nervous system, axons and growth cones contain mRNAs such as beta-actin, cofilin and RhoA, which are locally translated in response to guidance cues.
Arginylation of beta-actin regulates actin cytoskeleton and cell motility.
Impact
GeneRIF
Kashina et al., Philadelphia, United States. In Science, 2006
beta-actin was arginylated in vivo to regulate actin filament properties, beta-actin localization, and lamella formation in motile cells
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.
Impact
Singer et al., New York City, United States. In Nature, 2005
Localization of beta-actin messenger RNA to sites of active actin polymerization modulates cell migration during embryogenesis, differentiation and possibly carcinogenesis.
Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity.
Impact
Tsien et al., San Diego, United States. In Nat Biotechnol, 2005
The selected tetracysteine sequences, HRWCCPGCCKTF and FLNCCPGCCMEP, maintain their enhanced properties as fusions to either terminus of GFP or directly to beta-actin.
Extent of damage and repair in the p53 tumor-suppressor gene after treatment of myeloma patients with high-dose melphalan and autologous blood stem-cell transplantation is individualized and may predict clinical outcome.
Impact
Sfikakis et al., Athens, Greece. In J Clin Oncol, 2005
PATIENTS AND METHODS: The formation and subsequent repair of DNA damage (monoadducts and interstrand cross-links) in the p53 tumor-suppressor gene, the proto-oncogene N-ras, and the housekeeping gene beta-actin during the first 24 hours after treatment with high-dose melphalan (HDM; 200 mg/m2) supported by autologous blood stem-cell transplantation (ABSCT) was measured in blood leukocytes of 26 patients with MM.
More papers using beta-actin antibodies
Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
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Jang Sung Key, In PLoS ONE, 2001
... Mouse monoclonal antibodies against beta-actin and MAPK3 were purchased from Sigma and Abcam, respectively, and anti-mouse secondary ...
Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology.
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Unutmaz Derya, In PLoS ONE, 1997
... and beta-actin GFP transgenic mice were bred in ...
Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells
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Huh Sung-Oh et al., In The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 1995
... Beta-actin was obtained from Cell Signaling Technology (Beverly, MA) ...
Sequence selective double strand DNA cleavage by peptide nucleic acid (PNA) targeting using nuclease S1
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Permyakov Eugene A., In PLoS ONE, 1992
... anti-GCL (Santa Cruz Biotech; WB, 1/1000), rabbit anti-GCL (Sigma Aldrich, Brondby, Denmark; WB, 1/1000), mouse anti-beta-Actin (Ab6276; Abcam, Cambridge, UK; WB, 1/200.000);
A simple sequentially rejective multiple test procedure.
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Schwab Matthias et al., In Genome Medicine, 1978
... in normal and tumor tissues, commercial arrays including cDNA from 381 human tissues normalized to beta-actin were used (TissueScan, Origene technologies, Rockville, MD, USA) ...
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