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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tripartite motif containing 3

BERP, Trim3, RNF22
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: V1a, RBCC, alpha-actinin-4, Ubiquitin, HRs
Papers on BERP
Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels.
Van Kesteren et al., Amsterdam, Netherlands. In J Cell Biol, Dec 2015
We show that synaptic γ-actin levels are regulated by the E3 ubiquitin ligase TRIM3.
TRIM3 regulates the motility of the kinesin motor protein KIF21B.
Kneussel et al., Hamburg, Germany. In Plos One, 2012
Here we show that the ubiquitin E3 ligase TRIM3, also known as BERP, interacts with KIF21B via its RBCC domain.
Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors.
Mak et al., Toronto, Canada. In Proc Natl Acad Sci U S A, 2010
brain-expressed RING finger protein (BERP) is a gene whose expression is up-regulated in a p53-dependent manner
Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons.
Sheng et al., Cambridge, United States. In Plos One, 2009
postsynaptic scaffold GKAP is degraded and dendritic spine morphology is regulated by the TRIM3 ubiquitin ligase in rat hippocampal neurons
Glucocorticoid-induced gene tripartite motif-containing 63 (TRIM63) promotes differentiation of osteoblastic cells.
Inoue et al., Tokyo, Japan. In Endocr J, 2009
TRIM63 is a candidate for genes mediating the glucocorticoid-induced promotion of osteoblastic differentiation.
Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.
Yarden et al., Israel. In Dev Cell, 2009
Consistent with bifurcating roles, Lst2 physically binds Trim3/BERP, which interacts with Hrs and a complex that biases cargo recycling.
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Turck et al., São Paulo, Brazil. In Eur Arch Psychiatry Clin Neurosci, 2009
Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
Loss of heterozygosity of TRIM3 in malignant gliomas.
Hirth et al., Basel, Switzerland. In Bmc Cancer, 2008
Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene.
Gene expression patterns of hippocampus and cerebral cortex of senescence-accelerated mouse treated with Huang-Lian-Jie-Du decoction.
Zhang et al., Beijing, China. In Neurosci Lett, 2008
The results showed that HL has the significant modulating effects on age-related changes of the gene expressions in the hippocampus and cerebral cortex in SAMP8, which include genes that involved in signal transduction (Dusp12, Rps6ka1, Rab26, Penk1, Nope, Leng8, Syde1, Phb, Def8, Ihpk1, Tac2, Pik3c2a), protein metabolism (Ttc3, Amfr, Prr6, Ube2d2), cell growth and development (Ngrn, Anln, Dip3b, Acrbp), nucleic acid metabolism (Fhit, Itm2c, Cstf2t, Ddx3x, Ercc5, Pcgfr6), energy metabolism (Stub1, Uqcr, Nsf), immune response (C1qb), regulation of transcription (D1ertd161e, Gcn5l2, Ssu72), transporter (Slc17a7, mt-Co1), nervous system development (Trim3), neurogila cell differentiation (Tspan2) and 24 genes whose biological function and process were still unknown.
The molluscan RING-finger protein L-TRIM is essential for neuronal outgrowth.
van Kesteren et al., Amsterdam, Netherlands. In Mol Cell Neurosci, 2005
The tripartite motif proteins TRIM-2 and TRIM-3 have been put forward as putative organizers of neuronal outgrowth and structural plasticity.
CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling.
Bean et al., Houston, United States. In Mol Biol Cell, 2005
the endosome-associated protein hrs is a subunit of a protein complex containing actinin-4, BERP, and myosin V that is necessary for efficient TfR recycling but not for EGFR degradation
Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5.
Vincent et al., Vancouver, Canada. In Genomics, 2001
Here we have cloned and characterized the orthologous human BERP cDNA and gene (HGMW-approved symbol RNF22).
BERP, a novel ring finger protein, binds to alpha-actinin-4.
Vincent et al., Vancouver, Canada. In Biochem Biophys Res Commun, 2000
We recently identified BERP as a novel RING finger protein belonging to the RBCC protein family.
Cloning and characterization of a novel RING finger protein that interacts with class V myosins.
Vincent et al., Vancouver, Canada. In J Biol Chem, 1999
We have identified a novel protein (BERP) that is a specific partner for the tail domain of myosin V. Class V myosins are a family of molecular motors thought to interact via their unique C-terminal tails with specific proteins for the targeted transport of organelles.
Sensory interaction, brain activity, and reading ability in young adults.
Froning et al., In Int J Neurosci, 1980
Eight channels of visual (VERP), auditory (AERP), and bimodal (BERP) event related brain potential data were analyzed in order to assess the relationship between sensory interaction and reading ability.
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