Novel receptors for bacterial protein toxins.
Freiburg, Germany. In Curr Opin Microbiol, Feb 2015
Using optimized protocols and new methods novel toxin receptors have been identified, including metalloprotease ADAM 10 for Staphylococcus aureus α-toxin, laminin receptor Lu/BCAM for Escherichia coli cytotoxic necrotizing factor CNF1, lipolysis stimulated lipoprotein receptor (LSR) for Clostridium difficile transferase CDT and low-density lipoprotein receptor-related protein (LRP) 1 for Clostridium perfringens TpeL toxin.
Breast cancer prognostic biomarker using attractor metagenes and the FGD3-SUSD3 metagene.
New York City, United States. In Cancer Epidemiol Biomarkers Prev, 2014
RESULTS: The resulting test, called BCAM (Breast Cancer Attractor Metagenes), is universally applicable to all clinical subtypes and stages of breast cancer and does not make any use of breast cancer molecular subtype or hormonal status information, none of which provided additional prognostic value.
Role of Lu/BCAM glycoproteins in red cell diseases.
Paris, France. In Transfus Clin Biol, 2010
BCAM glycoproteins are the unique erythroid receptors of laminin alpha5 chain, a major component of the extracellular matrix and are involved in several erythrocyte diseases.
The Lutheran glycoprotein: a multifunctional adhesion receptor.
Durham, United States. In Transfusion, 2006
B-CAM spliceoform seems to be overexpressed by a variety of different malignant tumors and may be involved, along with other adhesion receptor proteins, in malignant transformation and tumor metastasis. (review)