Roles of E3 ubiquitin ligases in cell adhesion and migration.
Chapel Hill, United States. In Cell Adh Migr, 2010
Recent studies have demonstrated that a number of E3 ubiquitin ligases, including Cbl, Smurf1, Smurf2, HDM2, BCA2, SCF(beta-TRCP) and XRNF185, play important roles in cell adhesion and migration.
BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction.
Tokyo, Japan. In Plos Pathog, 2009
BCA2 accelerates the internalization and degradation of viral particles following their tethering to the cell surface and is a co-factor or enhancer for the tetherin-dependent restriction of HIV-1 release from infected cells.