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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Bcl2-associated X protein, a

Bax, zBax1
Top mentioned proteins: bcl-2, PrP, caspase-3, V1a, CAN
Papers using Bax antibodies
Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining.
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Song Libing, In PLoS ONE, 2009
... anti-Bax (6A7) IgGs were from BD Transduction Laboratories (Lexington, KY); anti-caveolin-1 (H-97), anti-Ku70 (A-9) and anti-Bax (N-20) IgGs were from Santa Cruz Biotechnology (Santa Cruz, CA); anti-cleaved ...
Wnt/β-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells
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Lai Gi-Ming et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2007
... Anti-Bcl2, anti-Bax, anti-β-catenin, and anti-survivin antibodies were purchased from Santa Cruz Biotechnology, Inc ...
Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-κB activation and nuclear factor-κB-regulated gene transcription through inactivating inhibitory κB kinase β
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Meili Ma et al., In Mediators of Inflammation, 2007
... of the original medicine) was purchased from Chiatai Qingchunbao Pharmaceutical Co., Ltd (China); Rabbit anti-mouse Bax antibody was purchased from Santa Cruz Biotechnology, Inc ...
DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells
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Berghe Wim Vanden et al., In Molecular Cancer, 2007
... Anti-IκBα, anti-p65 (C20), anti-p50 (NLS), anti-cRel (N), anti-RelB (C19), anti-Fra1(H50), anti-Nrf2 (C10), anti-Bax antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA), anti-p38, ...
Anti-apoptotic activity of Bcl-2 is enhanced by its interaction with RTN3.
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Linden Rafael, In PLoS ONE, 2006
... were from BD Biosciences, polyclonal against Rab4 was from Abcam, was from Sigma, monoclonal anti Bax (2D2), polyclonal anti Sec23 (E19) and monoclonal anti HA (F7) were purchased from Santa Cruz Biotechnology.
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Papers on Bax
Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming.
New
Impact
Götz et al., München, Germany. In Cell Stem Cell, Jan 2016
Surprisingly, mutants with reduced or no affinity for Bax demonstrated that Bcl-2 exerts this effect by an apoptosis-independent mechanism.
Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapy.
Review
New
Li et al., Shijiazhuang, China. In Acta Pharmacol Sin, Jan 2016
By using different monomers and composite prescriptions of TCM, it is possible to modulate the ratio of Bcl-2/Bax, regulate the expression of caspase proteases and mitochondrial transmembrane potential, increase the expression of Fas and p53, down-regulate NF-κB pathway and the expression of CHOP and survivin, and block cell cycle progression.
Disturbances in apoptosis of lamina propria lymphocytes in Crohn's disease.
New
Linke et al., Poznań, Poland. In Arch Med Sci, Jan 2016
Each CD patient underwent colonoscopy with tissue sampling from inflamed areas of the colon with the assessment of immunohistochemical expression of active caspase 3, Fas, tumour necrosis factor receptor 1 (TNFR1), Bcl-2, Bax, CD4 and CD8.
Protein-lipid interactions and non-lamellar lipidic structures in membrane pore formation and membrane fusion.
Review
New
Gilbert, Oxford, United Kingdom. In Biochim Biophys Acta, Jan 2016
Among these, membrane attack complex-perforin/cholesterol-dependent cytolysin (MACPF/CDC) family proteins, Bax/colicin family proteins and actinoporins are especially prominent and among the mechanisms believed to apply are the formation of non-lamellar (semi-toroidal or toroidal) lipidic structures.
Green Tea Polyphenols Attenuated Glutamate Excitotoxicity via Antioxidative and Antiapoptotic Pathway in the Primary Cultured Cortical Neurons.
New
Qin et al., Beijing, China. In Oxid Med Cell Longev, Dec 2015
Furthermore, our results demonstrated that green tea polyphenols restored the dysfunction of mitochondrial pro- or antiapoptotic proteins Bax, Bcl-2, and caspase-3 caused by glutamate.
Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1.
New
Yu et al., Xi'an, China. In Oxid Med Cell Longev, Dec 2015
BBR conferred cardioprotective effects by improving postischemic cardiac function, decreasing infarct size, reducing apoptotic index, diminishing serum creatine kinase and lactate dehydrogenase levels, upregulating SIRT1, Bcl-2 expressions, and downregulating Bax and caspase-3 expressions.
Factors affecting platinum sensitivity in cervical cancer.
New
Fukasawa et al., Tokyo, Japan. In Oncol Lett, Dec 2015
Each specimen was assessed for immunohistochemical expression of Ki-67, p53, B-cell lymphoma-2 (Bcl-2), Bcl-2-associated X protein (Bax), cleaved caspase-3, cyclooxygenase-2 (COX-2), and excision repair cross-complementation group 1 (ERCC1).
Evidence for altered osteoclastogenesis in splenocyte cultures from Cyp27b1 knockout mice.
Review
New
Atkins et al., Adelaide, Australia. In J Steroid Biochem Mol Biol, Dec 2015
In addition, the ratio of expression of the pro-apoptotic gene Bax to the pro-survival gene Bcl-2 was decreased in Cyp27b1 KO cultures, implying that these smaller osteoclasts survive longer than WT osteoclasts.
Bcl-2 family proteins as regulators of cancer cell invasion and metastasis: a review focusing on mitochondrial respiration and reactive oxygen species.
Review
New
Um, Seoul, South Korea. In Oncotarget, Dec 2015
Interestingly, cell invasion was recently found to be suppressed by multidomain pro-apoptotic members of the Bcl-2 family, such as Bax and Bak.
An interconnected hierarchical model of cell death regulation by the BCL-2 family.
New
Impact
Cheng et al., Kettering, United States. In Nat Cell Biol, Oct 2015
Multidomain pro-apoptotic BAX and BAK, once activated, permeabilize mitochondria to trigger apoptosis, whereas anti-apoptotic BCL-2 members preserve mitochondrial integrity.
Direct Activation of Bax Protein for Cancer Therapy.
Review
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Zhou et al., Galveston, United States. In Med Res Rev, Oct 2015
UNASSIGNED: Bax, a central cell death regulator, is an indispensable gateway to mitochondrial dysfunction and a major proapoptotic member of the B-cell lymphoma 2 (Bcl-2) family proteins that control apoptosis in normal and cancer cells.
The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes.
New
Impact
Stoffel et al., Zürich, Switzerland. In Nat Med, Jun 2015
Consequently, miR-200-induced T2D is suppressed by interfering with the signaling of Trp53 and Bax, a proapoptotic member of the B cell lymphoma 2 protein family.
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Impact
Flavell et al., New Haven, United States. In Cell, 2015
In the absence of active caspases, mitochondrial outer membrane permeabilization by Bax and Bak results in the expression of type I interferons (IFNs).
Analysis of functional polymorphisms in apoptosis-related genes in primary open angle glaucoma.
Mossböck et al., Graz, Austria. In Mol Vis, 2014
Therefore, we investigated the role of four functional apoptosis-related gene variants (Akt1 rs1130233, Bax rs4645878, Fas rs223476, and FasL rs763110) in patients with primary open angle glaucoma.
Structural basis for a pH-sensitive calcium leak across membranes.
Impact
Liu et al., New York City, United States. In Science, 2014
Human Bax inhibitor-1 (hBI-1) is an antiapoptotic protein that mediates a calcium leak and is representative of a highly conserved and widely distributed family, the transmembrane Bax inhibitor motif (TMBIM) proteins.
More papers using Bax antibodies
Siva is an apoptosis-selective p53 target gene important for neuronal cell death
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Prasad Kanteti V.S. et al., In Journal of Carcinogenesis, 2006
... monoclonalcytochrome C (BD Biosciences, 1:1,000); mouse monoclonal cytochrome C oxidase IV (COX IV) (Molecular Probes, Invitrogen, 1:1,000); Bax 6A7 (BD Biosciences); mouse monoclonal p53 (Cell ...
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
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Almeida Leonor M. et al., In Oxidative Medicine and Cellular Longevity, 2006
... Primary specific mouse monoclonal antibody to Bax and anti-mouse IgG secondary antibody were obtained from Abcam (Cambridge, UK); mouse monoclonal ...
Calreticulin exposure dictates the immunogenicity of cancer cell death.
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Cordes Nils, In PLoS ONE, 2006
... ); the down-regulation of Bak and Bax was performed with siRNAs (Hs_BAK_5, Hs_BAX_5 and Hs_BAX_10 HP Validated siRNAs, respectively) purchased from Qiagen (Hilden, Germany) ...
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
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Han Xiaonan et al., In EMBO Molecular Medicine, 2006
... Antibodies specific for STAT5, p65, p50, Bax and IκBα and β were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
The progress of integrated Chinese and Western medicine treatment on Glioma
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Huo Jiege et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2005
... , Bax, PARP antibodies was purchased from Cell Signaling Technology, USA ...
A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies.
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Jin Dong-Yan, In PLoS ONE, 2005
... Rabbit anti-GAPDH polyclonal antibody and mouse anti-Bax monoclonal antibody were purchased from Trevigen (Gaithersburg, MD) ...
Puerarin Decreases Lens Epithelium Cell Apoptosis Induced Partly By Peroxynitrite In Diabetic Rats.
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Morty Rory Edward, In PLoS ONE, 2005
... A mouse anti-α-actin monoclonal antibody, rabbit anti-Bcl-2 and anti-Bax polyclonal antibody were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
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Osawa Toshihiko et al., In Journal of Clinical Biochemistry and Nutrition, 2005
... The antibodies against Bcl-2 (100) and Bax were obtained from the Santa Cruz Biotechnology (Santa Cruz, CA) ...
Combined Adjuvant Cisplating and Ifosfamide Chemotherapy and Radiotherapy for Malignant Mixed Mullerian Tumors of the Uterus
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Diudea Dana et al., In World Journal of Surgical Oncology, 2005
... Baxpolyclonal1/50Dako ...
S100B expression modulates left ventricular remodeling after myocardial infarction in mice
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Verma Subodh et al., In Nature Communications, 2004
... Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice ...
Exposure geometry and spectral environment determine photobiological effects on the human eye.
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Osborne Neville N. et al., In Molecular Vision, 2004
... Monoclonal mouse anti-actin was from Chemicon (Southampton, UK), rabbit anti-human/rat Bax was from Alexis Corporation (UK distributor, Axxora UK Ltd, Nottingham, UK) ...
Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis
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Eckert Richard L., In PLoS ONE, 2004
... ) and anti-Bax were procured from Cell Signaling Technology (Beverly, MA) ...
Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.
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Di Cunto Ferdinando, In PLoS ONE, 2004
... Primary antibodies used for immunocytochemistry were rabbit polyclonal Hsp60 from Abcam (Cambridge, USA); mouse monoclonal Bax (clone 6A7) and mouse monoclonal cyt c (clone 6H2.B4) from BD Biosciences Pharmingen (San Jose, USA) ...
Down-regulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells
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Kim Sun Hyo et al., In Nutrition Research and Practice, 2004
... from BD Pharmingen (Franklin Lake, NJ, USA); antibodies against Fas, Fas ligand (Fas-L), Bcl-2, and Bax were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA); ...
Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
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McBride Heidi M. et al., In The Journal of Cell Biology, 2003
... Antibodies were obtained from the following providers: α-DRP1 (BD Biosciences), α-Hsp60 (Sigma-Aldrich), α–SUMO-1 (Zymed Laboratories), α-Bax (Upstate Biotechnology), α–cytochrome c (BD Biosciences), mouse IgG (Sigma-Aldrich), α-hFis1 ...
Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures
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Baik Tai-Kyoung et al., In Anatomy & Cell Biology, 2003
... Bax (#2774) human specific antibody was purchased from Cell Signaling Technology Inc ...
Temporally specific burst in cell proliferation increases hippocampal neurogenesis in protracted abstinence from alcohol.
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Mayeux Richard, In PLoS ONE, 2003
... They correspond to fusion cDNAs in which the mouse Bax cDNA (GenBank accession number L22472) was digested at the 5′end by HindIII and at the 3′end by EcoRI and cloned into the 3′end of either the pEYFP-C1 vector (#6005-1, Clontech, USA) or the pECFP-C1 ...
The weight of leptin in immunity.
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Ferreira Sérgio Teixeira, In PLoS ONE, 2003
... (sc-16566), pSTAT3 (sc-7993), SHP2 (sc-424), phosphotyrosine (sc-508), IRS-1 (sc-559), ObR (sc-8325), pERK (sc-7383), Bcl-2 (sc-492), Bax (sc-493), rabbit IgG-B (sc-2040), mouse IgG-B (sc-2039) and goat IgG-B (sc-2042) were from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase.
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Tanaka Sakae et al., In Biological Procedures Online, 2002
... Antibodies to Bid and Bax were purchased from Cell Signaling Technology ...
Spatial and temporal changes in Bax subcellular localization during anoikis
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Gilmore Andrew P. et al., In The Journal of Cell Biology, 2002
... Polyclonal anti-Bax recognizing the whole molecule was purchased from Santa Cruz Biotechnology, Inc ...
Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways
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Elzbieta Waszczykowska et al., In Clinical and Developmental Immunology, 2000
... The following primary monoclonal antibodies were used: Bax (Dako, Denmark) (1 : 650), TRAIL (Abcam, ...
Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene.
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Koo Hong Hoe et al., In Cell Biology International Reports, 2000
... Antibodies against caspase 8, caspase 9 and Bax were purchased from Santa Cruz Biotechnology; and antibodies against caspase ...
Human Bcl-2 protects against AMPA receptor-mediated apoptosis
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Qihui Cheng et al., In Mediators of Inflammation, 1999
... B P65 and anti-Bax antibody were purchased from Santa Cruz Biotechnology, Inc ...
ARL4, an ARF-like Protein That Is Developmentally Regulated and Localized to Nuclei and Nucleoli
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Aspenstrom Pontus, In PLoS ONE, 1999
... ATPase, Bax (Santa Cruz Biotechnology, Santa Cruz, CA, USA), ...
Induction of apoptosis by ursolic acid through activation of caspases and down-regulation of c-IAPs in human prostate epithelial cells
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Su Xiulan et al., In Journal of Biomedicine and Biotechnology, 1999
... mouse antihuman procaspase-3, mouse antihuman procaspase-8, mouse antihuman procaspase-9, mouse antihuman Bcl-2, and mouse antihuman Bax antibodies) were purchased from SANTA CRUZ Biotechnology.
Effect of recombinant human erythropoietin on endothelial cell apoptosis
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Kim Woo Taek et al., In Korean Journal of Pediatrics, 1998
... Primary antibodies included the following: Bcl-2 (1:1,000; Santa Cruz Biotechnology, Santa Cruz, CA, USA), Bax (1:1,000; Cell Signaling technolog, Danvers, MA, USA) ...
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
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Bleackley R. Chris et al., In The Journal of Experimental Medicine, 1998
... Rabbit polyclonal anti-Bax antiserum (N-20) was from Santa Cruz Biotechnology, Inc ...
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
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Chang Moon-Jeong et al., In Nutrition Research and Practice, 1998
... , Bax, and pAkt were purchased from Santa Cruz Biotechnology Inc ...
The Bcl-2 protein family: arbiters of cell survival
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Rennard Stephen I et al., In Respiratory Research, 1997
... Mouse anti-Bcl-2 antibody and mouse anti-Bax antibody were purchased from Santa Cruz Biotechnology, Inc ...
Injected cytochrome c induces apoptosis
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Martinou Jean-Claude et al., In The Journal of Cell Biology, 1997
... 1–21 of human Bax (06-499, lot 15670; Upstate Biotechnology), amino acids 11–30 of human Bax (Bax N-20 sc-493; Santa Cruz Biotechnology ...
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
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Youle Richard J. et al., In The Journal of Cell Biology, 1995
... COOH terminus of Bax, lacking serine 184 (YFP-20) in EYFP-C1, and the full-length point mutant Bax-S184V in ECFP-C1 (CLONTECH Laboratories, Inc.) were cloned ...
The mitochondrial permeability transition
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Tsujimoto Yoshihide et al., In The Journal of Cell Biology, 1994
An anti–human VDAC monoclonal antibody (31HL) and an anti–human Bax polyclonal antibody (N20) were obtained from Calbiochem and Santa Cruz Biotechnology, Inc., respectively ...
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
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Baron Roland et al., In The Journal of Cell Biology, 1993
... (San Diego, CA), and Bax (dilution 1:200) obtained from Santa Cruz Biotechnology ...
Temperature-dependent physiological stability of rat skeletal muscle in vitro.
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Vina Jose, In PLoS ONE, 1984
... Primary antibodies against Bcl-2 (sc-7382) and Bax (sc-493) were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
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