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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Basonuclin 2

Basonuclin 2
Top mentioned proteins: basonuclin, CAN, ACID, TOP, AGE
Papers on Basonuclin 2
Immunologic Overlap of Helper T-Cell Subtypes 17 and 22 in Erythrodermic Psoriasis and Atopic Dermatitis.
Nazarian et al., Boston, United States. In Jama Dermatol, Jul 2015
We evaluated immunohistochemical stains for CD3 and dual stains for CD4 and T-bet, GATA binding protein 3 (GATA3), signal transducer and activator of transcription 3 (STAT3), or basonuclin 2 (BNC2), which are transcription factors reported to be specific and mutually exclusive for TH1, TH2, TH17, and TH22 cells, respectively.
The zinc-finger protein basonuclin 2 is required for proper mitotic arrest, prevention of premature meiotic initiation and meiotic progression in mouse male germ cells.
Djian et al., Paris, France. In Development, 2014
We demonstrate here that the zinc-finger protein BNC2 is present in male but not in female germ cells.
Genome-wide investigation of regional blood-based DNA methylation adjusted for complete blood counts implicates BNC2 in ovarian cancer.
Goode et al., Rochester, United States. In Genet Epidemiol, 2014
The top associated CpG island (P = 7E-6) was located in the promoter/transcription start site of the human basonuclin 2 gene (BNC2), a known susceptibility gene for EOC risk identified through GWAS.
[Basonuclins and DISCO proteins: regulators of development in vertebrates and insects].
Djian et al., Paris, France. In Med Sci (paris), 2012
It remains to be found which targets are common to the two basonuclins and even to the DISCO proteins, and why certain cell types possess either basonuclin 1 or basonuclin 2, while others possess both.
Human balanced translocation and mouse gene inactivation implicate Basonuclin 2 in distal urethral development.
Zinn et al., Dallas, United States. In Eur J Hum Genet, 2011
Bnc2(-/-) mice of both sexes displayed a high frequency of distal urethral defects; heterozygotes showed similar defects with reduced penetrance.
Basonuclins and disco: Orthologous zinc finger proteins essential for development in vertebrates and arthropods.
Djian et al., Paris, France. In Biochimie, 2011
Basonuclin 1 and the recently discovered basonuclin 2 are vertebrate proteins with multiple paired C(2)H(2) zinc fingers.
Integrative analysis of the human cis-antisense gene pairs, miRNAs and their transcription regulation patterns.
Kuznetsov et al., Singapore, Singapore. In Nucleic Acids Res, 2010
Specifically, we revealed complex SA structural-functional gene module composing the protein-coding genes, WDR6, DALRD3, NDUFAF3 and ncRNA precursors, mir-425 and mir-191, which could provide downregulation of ncRNA pathway via direct targeting DICER1 and basonuclin 2 transcripts by mir-425 and mir-191 in normal spermatogenesis, but this mechanism is switched off in severe teratozoospermia.
Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.
Koeffler et al., Los Angeles, United States. In Int J Cancer, 2009
(1.2 Mb): this region harbors only 1 known gene, basonuclin 2 (BNC2).
Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins.
Djian et al., Paris, France. In Proc Natl Acad Sci U S A, 2009
Results show that basonuclin 2 is essential for the multiplication of craniofacial mesenchymal cells during embryogenesis.
The human basonuclin 2 gene has the potential to generate nearly 90,000 mRNA isoforms encoding over 2000 different proteins.
Djian et al., Paris, France. In Genomics, 2007
We demonstrate here that human basonuclin 2 (bn2; approved gene symbol BNC2) transcripts are initiated from six promoters, are alternatively spliced at multiple positions, and are polyadenylated at four sites.
Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions.
Djian et al., Paris, France. In Proc Natl Acad Sci U S A, 2006
Data show that basonuclin (Bn)2 but not bn1 colocalizes with SC35 in nuclear speckles, and may have a function in nuclear processing of mRNA.
Identification of Basonuclin2, a DNA-binding zinc-finger protein expressed in germ tissues and skin keratinocytes.
Sinha et al., Buffalo, United States. In Genomics, 2004
gene expression profiling; structural and functional similarities with Basonuclin 1 suggest that Basonuclin2 may play an analogous function in germ cells and skin keratinocytes
Basonuclin 2: an extremely conserved homolog of the zinc finger protein basonuclin.
Djian et al., Paris, France. In Proc Natl Acad Sci U S A, 2004
the extreme conservation of the basonuclin 2 amino acid sequence across vertebrates suggests that basonuclin 2 serves an important function, presumably as a regulatory protein of DNA transcription
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