[Analysis of disease-pathway by identifying susceptible genes to primary biliary cirrhosis].
Nagasaki, Japan. In Nihon Rinsho Meneki Gakkai Kaishi, 2011
Among 21 non-HLA susceptibility loci for PBC identified in GWASs of European descent, 10 loci (CD80, IKZF3, IL7R, NFKB1, STAT4, TNFAIP2, CXCR5, MAP3K7IP1, rs6974491, DENND1B) showed significant associations in the Japanese population.
Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer.
Oklahoma City, United States. In Curr Mol Med, 2009
In light of existing knowledge on interconnected pathways of pro-inflammatory mediators (leukotrienes, chemokines (IL8, SDF-1 alpha, MIP-1 alpha, MCP-1,2 etc), and cytokines (IL3, IL6, IL12, IL-1 beta, GM-CSF, B94, TNF-alpha etc)), the anti-inflammatory properties of pro-resolving mediators in preventing chronic inflammation which leads to carcinogenesis needs further understanding.