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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.


B23, NPM, NPM1
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009] (from NCBI)
Papers using B23 antibodies
Frequent pathway mutations of splicing machinery in myelodysplasia.
Pelicci Pier Giuseppe et al., In Frontiers in Oncology, 2010
... The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model.
The survival-promoting peptide Y-P30 enhances binding of pleiotrophin to syndecan-2 and -3 and supports its neuritogenic activity.
Bogyo Matthew, In PLoS ONE, 2007
... sc-8334; Santa Cruz Biotechnology, Heidelberg, Germany); α-GST (glutathione S-transferase, sc-57753; Santa Cruz Biotechnology, Heidelberg, Germany); α-NPM1 (nucleophosmin, #3542 Cell Signaling); α-Tasp ...
Nucleolar trafficking is essential for nuclear export of intronless herpesvirus mRNA.
Glaunsinger Britt A., In PLoS Pathogens, 2005
... Antibodies against SC-35, Flag, Myc and Aly (Sigma), GFP and mCherry (Clontech), B23 (Santa Cruz), KSHV gB (Abcam) and GAPDH (Abcam) were ...
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi.
Burns Jorge Sans, In PLoS ONE, 2002
... Mouse anti-GFP (Covance Research Products) anti-myc (myc-Tag 9B11) (DSHB), anti-B23/Nucleophosmin (AB10530; Abcam) and anti-UBF (H00007343-M01), goat ...
Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4+ cell clone 1–10 (MAGIC-5)
Speck Roberto F., In PLoS ONE, 2000
... approved by the Ethics Committee for Animal Care and Use of Kumamoto University (Approval ID, B23-181 R1: Analysis of immune responses against viral diseases by using humanized and HLA transgenic mice) ...
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Papers on B23
Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1.
Curiel et al., Birmingham, United States. In Virology, 2012
Adenoviral protein V participates in a process of viral assembly through NPM1.
Mutated regions of nucleophosmin 1 elicit both CD4(+) and CD8(+) T-cell responses in patients with acute myeloid leukemia.
Schmitt et al., Ulm, Germany. In Blood, 2012
NPM1(mut) induces specific T-cell responses of CD4(+) and CD8(+) T cells and therefore is a promising target for specific immunotherapies in acute myeloid leukemia.
Structure of nucleophosmin DNA-binding domain and analysis of its complex with a G-quadruplex sequence from the c-MYC promoter.
Federici et al., Sesto Fiorentino, Italy. In J Biol Chem, 2012
present the solution structure of the NPM1-C70 domain and NMR analysis of its interaction with a c-MYC-derived G-quadruplex. These data were used to calculate an experimentally restrained molecular docking model for the complex
In silico studies of potential phosphoresidues in the human nucleophosmin/B23: its kinases and related biological processes.
Pons et al., Havana, Cuba. In J Cell Biochem, 2012
study suggesst that B23 phosphorylation is related to cellular processes such as apoptosis, cell survival, cell proliferation, and response to DNA damage stimulus, in which these kinases are involved
Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells.
Liu et al., State College, United States. In J Biol Chem, 2012
a mechanistic link between elevated NPM1 expression and depressed ATF5 in HCC and suggests that regulation of ATF5 by NPM1 plays an important role in the proliferation and survival of HCC.
More papers using B23 antibodies
A quantitative assay for HIV DNA integration in vivo.
Vij Neeraj, In PLoS ONE, 2000
... Rabbit polyclonal anti-HA antibodies were purchased from Santa Cruz Biotechnology, mouse anti-B23 (nucleophosmin) antibody from Abcam, Alexa 568 conjugated goat ...
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