Move over ZFNs
In PLoS ONE, 2010
... The designed amino acid sequences of TALENs (designated as B2L, B2R, B3L, and B3R) were converted to DNA sequences that correspond with the codon usage in silkworm and then synthesized using a commercial service (GenScript).
Kinins and peptide receptors.
In Biol Chem, Jan 2016
The biologically active effector entity of RAS is angiotensin receptor-1 (AT-1R), and that of KKS is bradykinin B2 receptor (B2R).
A randomized trial of icatibant in ACE-inhibitor-induced angioedema.
Düsseldorf, Germany. In N Engl J Med, Mar 2015
METHODS: In this multicenter, double-blind, double-dummy, randomized phase 2 study, we assigned patients who had ACE-inhibitor-induced angioedema of the upper aerodigestive tract to treatment with 30 mg of subcutaneous icatibant, a selective bradykinin B2 receptor antagonist, or to the current off-label standard therapy consisting of intravenous prednisolone (500 mg) plus clemastine (2 mg).
Ottawa, Canada. In Unknown Journal, 0001
Icatibant, a selective bradykinin B2 receptor antagonist, has been approved in many countries worldwide for the symptomatic treatment of acute attacks of types I and II hereditary angioedema (HAE) in adults since 2008.