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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Dynein, axonemal, light chain 1

axonemal dynein light chain 1, DNA LI
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011] (from NCBI)
Top mentioned proteins: PrP, IIa, bcl-2, CENPF, PCNA
Papers on axonemal dynein light chain 1
Knockdown of MAP4 and DNAL1 produces a post-fusion and pre-nuclear translocation impairment in HIV-1 replication.
Hope et al., Chicago, United States. In Virology, 2012
DNAL1 and MAP4 may exert their functions in the HIV life cycle at reverse transcription, prior to nuclear translocation.
Primary ciliary dyskinesia caused by homozygous mutation in DNAL1, encoding dynein light chain 1.
Parvari et al., Beersheba, Israel. In Am J Hum Genet, 2011
DNAL1 mutation could help to elucidate the interaction between the DNAL1 to dynein heavy chain and to tubulin.
Caspase-3 immunohistochemical expression is a marker of apoptosis, increased grade and early recurrence in intracranial meningiomas.
Patsouris et al., Athens, Greece. In Apoptosis, 2007
In both instances, the labeling index (LI) was significantly correlated with ss-DNA LI (p=0.038 and p=0.018).
Predictive markers of pituitary adenoma behavior.
Kontogeorgos, Athens, Greece. In Neuroendocrinology, 2005
Monosomy or partial loss of chromosome 11 in adenomas with a normal or increased DNA LI indicates complex genomic abnormalities of chromosomes, other than chromosome 11.
Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.
Omran et al., Freiburg, Germany. In Am J Respir Cell Mol Biol, 2005
identification of the human (DNAL1) ortholog of the Chlamydomonas LC1-gene; protein interaction studies demonstrated binding of DNAL1 and DNAH5; DNAL1 considered a candidate for primary ciliary dyskinesia
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