The stage-specific testicular germ cell apoptotic response to low-dose radiation and 2,5-hexanedione combined exposure. II: qRT-PCR array analysis reveals dose dependent adaptive alterations in the apoptotic pathway.
Providence, United States. In Toxicol Pathol, 2014
The apoptosis PCR arrays identified significant dose-dependent treatment effects on several genes, with downregulation of death receptor 5 (DR5), Naip2, Sphk2, Casp7, Aven, Birc3, and upregulation of Fas.
Aven-dependent activation of ATM following DNA damage.
Durham, United States. In Curr Biol, 2008
These results identify Aven as a new ATM activator and describe a positive feedback loop operating between Aven and ATM; in aggregate, these findings place Aven, a known apoptotic inhibitor, as a critical transducer of the DNA-damage signal.
Adolescent sexuality and disability.
New York City, United States. In Phys Med Rehabil Clin N Am, 2002
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