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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Enhancer of mRNA decapping 4

Autoantigen, Ge-1
Top mentioned proteins: CAN, HAD, ACID, Phosphogluconate Dehydrogenase, MHC
Papers using Autoantigen antibodies
Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body
Giannakakou Paraskevi et al., In The Journal of Cell Biology, 2004
... Primary antibodies used were rat anti–α-tubulin (YL1/2; EMD), mouse anti–HIF-1α (BD), rabbit anti-actin (Sigma-Aldrich), mouse anti–GE-1 (sc-8418; Santa Cruz Biotechnology, Inc.), mouse anti-Ago2 (Abcam), ...
Papers on Autoantigen
Splenic Long-Lived Plasma Cells Promote the Development of Follicular Helper T Cells during Autoimmune Responses.
Youn et al., Seoul, South Korea. In J Immunol, Feb 2016
Autoantigen-pulsed K/BxNsf PCs selectively polarized cognate CD4(+) T cells toward the expression of molecules necessary for Tfh development and function.
Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes.
Michels et al., Aurora, United States. In Curr Diab Rep, Dec 2015
Type 1 diabetes is a chronic autoimmune disease resulting from T cell-mediated destruction of insulin-producing beta cells within pancreatic islets.
Targeting Anti-Insulin B Cell Receptors Improves Receptor Editing in Type 1 Diabetes-Prone Mice.
Thomas et al., Nashville, United States. In J Immunol, Dec 2015
Physiologic, circulating insulin increased RAG-2 expression and was associated with BCR replacement that eliminated autoantigen recognition in a proportion of developing anti-insulin B lymphocytes.
Epiplakin is a Paraneoplastic Pemphigus Autoantigen and Related to Bronchiolitis Obliterans in Japanese Patients.
Hashimoto et al., Kurume, Japan. In J Invest Dermatol, Nov 2015
UNASSIGNED: All plakin family proteins are known to be autoantigens in paraneoplastic pemphigus (PNP).
Autoantigen Microarray for High-throughput Autoantibody Profiling in Systemic Lupus Erythematosus.
Li et al., Changsha, China. In Genomics Proteomics Bioinformatics, Aug 2015
The autoantigen arrays carrying a wide variety of self-antigens, such as cell nuclear components (nucleic acids and associated proteins), cytoplasmic proteins, phospholipid proteins, cell matrix proteins, mucosal/secreted proteins, glomeruli, and other tissue-specific proteins, have been used for screening of autoantibody specificities associated with different manifestations of SLE.
Recent pathogenetic advances in ANCA-associated vasculitis.
Nachman et al., Chapel Hill, United States. In Presse Med, Jun 2015
Epigenetic modification of autoantigen genes appears to contribute to perpetuation of disease and possibly relapse risk.
DFS70/LEDGFp75: An Enigmatic Autoantigen at the Interface between Autoimmunity, AIDS, and Cancer.
Casiano et al., Loma Linda, United States. In Front Immunol, 2014
Here, we discuss briefly our current understanding of this enigmatic autoantigen and potential scenarios leading to its targeting by the immune system.
Production of the Main Celiac Disease Autoantigen by Transient Expression in Nicotiana benthamiana.
Petruccelli et al., La Plata, Argentina. In Front Plant Sci, 2014
The main CD autoantigen, human tissue transglutaminase (TG2), is a challenge for the different expression systems available since its cross-linking activity affects cellular processes.
Novel therapies in the management of type I diabetes mellitus.
Ludvigsson, Linköping, Sweden. In Panminerva Med, 2012
Autoantigen treatment is a promising concept, and has the great advantage of being easy, practical with no adverse events.
Autoantigen discovery with a synthetic human peptidome.
Elledge et al., Cambridge, United States. In Nat Biotechnol, 2011
Here we present a synthetic representation of the complete human proteome, the T7 peptidome phage display library (T7-Pep), and demonstrate its application to autoantigen discovery.
Drosophila Ge-1 promotes P body formation and oskar mRNA localization.
Ephrussi et al., Heidelberg, Germany. In Plos One, 2010
Findings suggest an important role of dGe-1 in optimization of the osk mRNA localization process required for patterning the Drosophila embryo.
T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells.
Geiger et al., Memphis, United States. In Immunity, 2010
Treg and Tconv cell TCR repertoires were distinct, and autoantigen-specific Treg and Tconv cells were enriched in diseased tissue.
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event.
Vignali et al., Memphis, United States. In Immunity, 2009
Autoantigen-specific T cells that accumulate in islets, but do not cause diabetes, were also unaffected by the presence of diabetogenic T cells.
The C-terminal region of Ge-1 presents conserved structural features required for P-body localization.
Izaurralde et al., Martinsried, Germany. In Rna, 2008
The three-dimensional crystal structure of the most conserved region of the Drosophila melanogaster Ge-1 C-terminal domain was determined.
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity.
Reith et al., Genève, Switzerland. In Immunity, 2008
We demonstrate here that, although either CD4(+) or CD8(+) thymocytes are sufficient to sustain formation of a well-defined medulla, expansion of the mature mTEC population requires autoantigen-specific interactions between positively selected CD4(+) thymocytes bearing autoreactive T cell receptor (TCR) and mTECs displaying cognate self-peptide-MHC class II complexes.
Widespread translational inhibition by plant miRNAs and siRNAs.
Voinnet et al., Strasbourg, France. In Science, 2008
Also as in animals, the decapping component VARICOSE (VCS)/Ge-1 is required for translational repression by miRNAs, which suggests that the underlying mechanisms in the two kingdoms are related.
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