Autoantigen Microarray for High-throughput Autoantibody Profiling in Systemic Lupus Erythematosus.
Changsha, China. In Genomics Proteomics Bioinformatics, Aug 2015
The autoantigen arrays carrying a wide variety of self-antigens, such as cell nuclear components (nucleic acids and associated proteins), cytoplasmic proteins, phospholipid proteins, cell matrix proteins, mucosal/secreted proteins, glomeruli, and other tissue-specific proteins, have been used for screening of autoantibody specificities associated with different manifestations of SLE.
Autoantigen discovery with a synthetic human peptidome.
Cambridge, United States. In Nat Biotechnol, 2011
Here we present a synthetic representation of the complete human proteome, the T7 peptidome phage display library (T7-Pep), and demonstrate its application to autoantigen discovery.