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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 01 Aug 2015.

IplI-aurora-like kinase

Aurora B, Aurora B kinase, DmAurora B
Top mentioned proteins: Aurora, Histone, CAN, INCENP, V1a
Papers using Aurora B antibodies
The c-myc Insulator Element and Matrix Attachment Regions Define the c-myc Chromosomal Domain.
Supplier
Chadwick Brian P., In PLoS ONE, 2002
... cdk inhibitors or mitosis kinase inhibitors: 50 mM of hydroxyurea (Tocris Bioscience), 1 mM of the Aurora B Kinase inhibitor ZM447439 (Tocris Bioscience) or 100 nM ...
Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product
Supplier
Cimini Daniela, In PLoS ONE, 1989
... Aurora B kinase inhibitor, ZM447439 (Tocris Biosciences, USA), was dissolved ...
Papers on Aurora B
Chromosome segregation regulation in human zygotes: altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex.
New
Baart et al., Rotterdam, Netherlands. In Hum Reprod, 29 Aug 2015
In zygotes, nuclear envelope breakdown was monitored by time-lapse imaging to allow timed incubations with specific inhibitors to arrest at prometaphase and metaphase, and to interfere with Haspin and Aurora B/C kinase activity.
Phase II Intergroup Trial of Alisertib in Relapsed and Refractory Peripheral T-Cell Lymphoma and Transformed Mycosis Fungoides: SWOG 1108.
New
Impact
Friedberg et al., Seattle, United States. In J Clin Oncol, 20 Aug 2015
Aurora B kinase was more commonly overexpressed than AAK in tumor specimens.
D-Aspartate Induces Proliferative Pathways in Spermatogonial GC-1 Cells.
New
Baccari et al., Caserta, Italy. In J Cell Physiol, 19 Aug 2015
D-Asp induced phosphorylation of ERK and Akt proteins, stimulated expression of PCNA and Aurora B, and enhanced mRNA synthesis and protein expression of P450 aromatase and protein expressionof Estrogen Receptor β (ERβ).
Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one derivatives as Aurora A kinase inhibitors: LQTA-QSAR analysis and detailed systematic validation of the developed model.
New
Yadav et al., Vadodara, India. In Mol Divers, 17 Aug 2015
UNASSIGNED: Aurora kinases are sub-divided into Aurora A, Aurora B, and Aurora C kinases that are considered as prospective targets for a new class of anticancer drugs.
Multiple Levels of Regulation of Sororin by Cdk1 and Aurora B.
New
Taylor et al., Toledo, United States. In J Cell Biochem, 14 Aug 2015
Aurora B phosphorylation of Sororin may play a similar role as Cdk1.
Kinetochore-microtubule error correction is driven by differentially regulated interaction modes.
New
Impact
Tanaka et al., Oxford, United Kingdom. In Nat Cell Biol, Apr 2015
To establish bi-orientation, aberrant kinetochore-microtubule attachments are disrupted (error correction) by aurora B kinase (Ipl1 in budding yeast).
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.
New
Impact
Ellenberg et al., Heidelberg, Germany. In Nat Biotechnol, Apr 2015
We also analyzed the cell-cycle-dependent dynamics of the mitotic kinase complex Aurora B/INCENP and showed how a rise in Aurora concentration triggers two-step complex formation.
The aurora kinases in cell cycle and leukemia.
Review
New
Crispino et al., Chicago, United States. In Oncogene, Mar 2015
The Aurora kinases, which include Aurora A (AURKA), Aurora B (AURKB) and Aurora C (AURKC), are serine/threonine kinases required for the control of mitosis (AURKA and AURKB) and meiosis (AURKC).
The chromosomal passenger complex (CPC) as a key orchestrator of orderly mitotic exit and cytokinesis.
Review
New
Lee et al., Singapore, Singapore. In Front Cell Dev Biol, Dec 2014
Recent studies reveal that controlling CPC localization and Aurora B kinase activity also serves as a key surveillance mechanism for the orderly mitotic exit.
Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.
New
Yao et al., Hefei, China. In Sci Rep, Dec 2014
Here, we describe a novel pathway involving an Aurora B-PLK1 axis for regulation of MCAK activity in mitosis.
Negative feedback at kinetochores underlies a responsive spindle checkpoint signal.
New
Impact
Saurin et al., Utrecht, Netherlands. In Nat Cell Biol, Dec 2014
Active SAC signalling recruits PP2A-B56 to kinetochores where it antagonizes Aurora B to promote PP1 recruitment.
Aurora kinase inhibitor patents and agents in clinical testing: an update (2011 - 2013).
Review
New
Coumar et al., Zhengzhou, China. In Expert Opin Ther Pat, Sep 2014
Preliminary evidence suggests that the use of selective Aurora A inhibitors could avoid Aurora B-mediated neutropenia in clinical settings.
The dynamic protein Knl1 - a kinetochore rendezvous.
Review
New
Bolanos-Garcia et al., Québec, Canada. In J Cell Sci, Sep 2014
We present emerging roles of the protein interaction motifs present in Knl1, including the RVSF, SILK, MELT and KI motifs, and their role in the recruitment and regulation of the SAC proteins Bub1, BubR1, Bub3 and Aurora B. Finally, we explore how the regions of low structural complexity that characterize Knl1 are implicated in the cooperative interactions that mediate binding partner recognition and scaffolding activity by Knl1.
An up-date on newly discovered immunohistochemical biomarkers for the diagnosis of human testicular germ cell tumors.
Review
New
Chieffi et al., Caserta, Italy. In Histol Histopathol, Aug 2014
For proper diagnosis of the different histological subgroups, immunohistochemistry is required using different molecular markers, such as Aurora B, GPR30, Nek2, HMGA1, HMGA2, and others, and they could represent useful novel molecular targets for antineoplastic strategies.
Feedback control of chromosome separation by a midzone Aurora B gradient.
New
Impact
Maiato et al., Porto, Portugal. In Science, Aug 2014
A midzone-associated Aurora B gradient was found to monitor chromosome position along the division axis and to prevent premature chromosome decondensation by retaining Condensin I. PP1/PP2A phosphatases counteracted this gradient and promoted chromosome decondensation and NER.
Binucleine 2, an isoform-specific inhibitor of Drosophila Aurora B kinase, provides insights into the mechanism of cytokinesis.
GeneRIF
Eggert et al., In Acs Chem Biol, 2010
Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.
INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila.
GeneRIF
Carmena et al., Cambridge, United States. In Dev Cell, 2006
INCENP binds to the cohesion protector protein MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.
Spindle assembly and cytokinesis in the absence of chromosomes during Drosophila male meiosis.
GeneRIF
Gatti et al., Roma, Italy. In J Cell Biol, 2003
This protein accumulates at the mid-zones of chromosome-free spindles.
Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes.
GeneRIF
González et al., Heidelberg, Germany. In Embo J, 2002
Aurora B interacts with and requires the Cdc37/Hsp90 complex for its stability.
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