Targeting Mitosis in Cancer: Emerging Strategies.
Toronto, Canada. In Mol Cell, Dec 2015
This reasoning stimulated our development of novel inhibitors targeting the critical regulators of genomic stability and the mitotic checkpoint: AURKA, PLK4, and Mps1/TTK.
Functions of Aurora kinase C in meiosis and cancer.
United States. In Front Cell Dev Biol, 2014
The mammalian genome encodes three Aurora kinase protein family members: A, B, and C. While Aurora kinase A (AURKA) and B (AURKB) are found in cells throughout the body, significant protein levels of Aurora kinase C (AURKC) are limited to cells that undergo meiosis (sperm and oocyte).