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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


Aubergine, Aub
Top mentioned proteins: Piwi, Cdc4, V1a, CAN, Dicer
Papers on Aubergine
Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms.
Zamore et al., Worcester, United States. In Mol Cell, Oct 2015
In Drosophila ovarian germ cells, PIWI-interacting RNAs (piRNAs) direct Aubergine and Argonaute3 to cleave transposon transcripts and instruct Piwi to repress transposon transcription, thereby safeguarding the germline genome.
Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper.
Aravin et al., Pasadena, United States. In Mol Cell, Sep 2015
In Drosophila, two Piwi proteins, Aubergine (Aub) and Argonaute-3 (Ago3), localize to perinuclear "nuage" granules and use guide piRNAs to target and destroy transposable element transcripts.
Aubergine iCLIP Reveals piRNA-Dependent Decay of mRNAs Involved in Germ Cell Development in the Early Embryo.
Simonelig et al., Montpellier, France. In Cell Rep, Sep 2015
Here, we perform iCLIP with the PIWI protein Aubergine (Aub) and identify hundreds of maternal mRNAs interacting with Aub in the early Drosophila embryo.
Tudor-domain containing proteins act to make the piRNA pathways more robust in Drosophila.
Siomi et al., Tokyo, Japan. In Fly (austin), May 2015
The de novo primary pathway in Drosophila ovaries produces primary piRNAs for two PIWI members, Piwi and Aub.
Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding.
Lockwood et al., New Haven, United States. In Plos One, 2014
Abnormal uterine bleeding (AUB) is the major side effect of, and cause for, discontinuation of LAPCs.
Transposition-driven genomic heterogeneity in the Drosophila brain.
Waddell et al., Worcester, United States. In Science, 2013
The Piwi-interacting RNA (piRNA) proteins Aubergine and Argonaute 3, known to suppress transposons in the fly germline, are expressed in the brain and appear less abundant in αβ MB neurons.
UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery.
Theurkauf et al., Worcester, United States. In Cell, 2012
The nuclear DEAD box protein UAP56 has been previously implicated in mRNA splicing and export, whereas the DEAD box protein Vasa has an established role in piRNA production and localizes to nuage with the piRNA binding PIWI proteins Ago3 and Aub.
piRNA pathway and the potential processing site, the nuage, in the Drosophila germline.
Kai et al., Singapore, Singapore. In Dev Growth Differ, 2012
In contrast, the secondary processing pathway functions only in the germline cells where piRNAs are amplified in a feed-forward loop and require the Piwi-family proteins Aubergine and Argonaute3.
Aubergine is a component of a nanos mRNA localization complex.
Gavis et al., Princeton, United States. In Dev Biol, 2011
results support a role for Aub, independent of its function in RNA silencing, as a component of a nos mRNA localization complex
Novel role of specific Tudor domains in Tudor-Aubergine protein complex assembly and distribution during Drosophila oogenesis.
Arkov et al., Murray, United States. In Biochem Biophys Res Commun, 2010
this study provides the first direct evidence that interaction surface of Tud for Aub is composed of multiple Tud domains and our data suggest that in addition to the segment containing domains 7-11, the other Tud domains are used for Aub interaction.
Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo.
Simonelig et al., Montpellier, France. In Nature, 2010
Aubergine, one of the Argonaute proteins in the piRNA pathway, is present in a complex with Smaug, CCR4, nos mRNA and piRNAs that target the nos 3' untranslated region, in the bulk of the embryo.
Structural basis for methylarginine-dependent recognition of Aubergine by Tudor.
Xu et al., Beijing, China. In Genes Dev, 2010
Cocrystal structures of an extended Tudor domain (eTud) of Drosophila Tudor with methylated peptides of Aubergine, a Piwi family protein, reveal that sDMA is recognized by an asparagine-gated aromatic cage
piRNA-mediated silencing in Drosophila germlines.
Siomi et al., Tokyo, Japan. In Semin Cell Dev Biol, 2010
After maturing from the primary transcripts, piRNAs are specifically loaded onto germline-specific Argonaute proteins - Argonaute3, Aubergine and Piwi - collectively referred to as PIWI proteins.
Maternal impairment of transposon regulation in Drosophila melanogaster by mutations in the genes aubergine, piwi and Suppressor of variegation 205.
Bjorklund et al., Saint Paul, United States. In Genet Res (camb), 2010
TP5 represses the excision of other P elements in the germ line through a combination of maternal and zygotic effects. The maternal component of this repression is impaired by heterozygous mutations in the aubergine gene.
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization.
Mourelatos et al., Philadelphia, United States. In Rna, 2010
Germ plasm assembly requires symmetrically dimethylated modification of Aub by dPRMT5, which, in turn, is required for binding to Tudor.
A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila.
Siomi et al., Tokyo, Japan. In Nature, 2009
PIWI-interacting RNAs (piRNAs) silence retrotransposons in Drosophila germ lines by associating with the PIWI proteins Argonaute 3 (AGO3), Aubergine (Aub) and Piwi.
Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies.
Zamore et al., Worcester, United States. In Cell, 2009
piRNAs are thought to derive from long transcripts spanning transposon-rich genomic loci and to direct an autoamplification loop in which an antisense piRNA, bound to Aubergine or Piwi protein, triggers production of a sense piRNA bound to the PIWI protein Argonaute3 (Ago3).
[A novel class of testis-specific small RNAs: piRNAs].
Xiong et al., Wuhan, China. In Zhonghua Nan Ke Xue, 2008
The other is the PIWI subfamily, including PIWI, Aubgine (AUB) and AGO3, exclusively expressed in the testis.
Pathophysiology of endometrial bleeding.
Ferenczy, Montréal, Canada. In Maturitas, 2003
METHODS: Review of pertinent literature focusing on the histology and pathophysiology of normal and abnormal uterine bleeding (AUB).
Therapies for the treatment of abnormal uterine bleeding.
Robins, Cincinnati, United States. In Curr Womens Health Rep, 2001
Abnormal uterine bleeding (AUB) is one of the most common disorders encountered by the gynecologist.
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