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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Attractin

attractin, Atrn
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, May 2011] (from NCBI)
Top mentioned proteins: fibrillin-1, V1a, CAN, HAIR, CD26
Papers on attractin
Identification of atypical ATRNL1 insertion to EML4-ALK fusion gene in NSCLC.
New
Dvorakova et al., Brno, Czech Republic. In Lung Cancer, Mar 2015
However, a detailed RT-PCR analysis and sequencing revealed an unexpected 138 bp insertion of attractin-like 1 (ATRNL1) gene into the EML4-ALK fusion gene.
Bioinformatic prediction of Trichoplax adhaerens regulatory peptides.
New
Nikitin, Moscow, Russia. In Gen Comp Endocrinol, Mar 2015
Extensive transcriptome, genome, and predicted proteome mining allowed us to predict four insulins, at least five short peptide precursors, one granulin, one paracrine regulator of cell growth, and one complex temptin-attractin pheromone signaling system.
[Antioxidative and antiapoptotic effects of the Attractin gene on Sertoli cells in mice].
Xiong et al., In Zhonghua Nan Ke Xue, 2014
OBJECTIVE: To evaluate the effects of Attractin (Atrn) silence on the anti-oxidative and anti-apoptotic abilities of TM4 Sertoli cells and its influence on the expressions of superoxide dismutase (SOD) and caspase6 in the cells.
New clues to identify proteins correlated with Attractin.
Xiong et al., Wuhan, China. In Andrologia, 2014
In our previous study, the age-dependent testis vacuolisation and sperm dysfunction were found in Attractin (Atrn)-deficient mice, Atrn(mg-3J) , which is a null or nearly null allele.
Proteomic analysis of human osteoarthritis synovial fluid.
Pandey et al., Pune, India. In Clin Proteomics, 2013
We identified 300 proteins using lectin affinity chromatography, including the glycoproteins afamin (AFM), attractin (ATRN), fibrillin 1 (FBN1), transferrin (TF), tissue inhibitor of metalloproteinase 1 (TIMP1) and vasorin (VSN).
Changes in expression and distribution of attractin in the testes of rats at different developmental stages.
Zhan et al., Nanjing, China. In Int J Mol Med, 2013
Attractin (Atrn), an autosomal recessive gene, is widely expressed in the body and displays multiple physiological and pathological functions in different types of tissues.
RML prions act through Mahogunin and Attractin-independent pathways.
Carlson et al., Great Falls, United States. In Prion, 2013
Mahogunin ring finger-1 (Mgrn1) and Attractin (Atrn) null mutant mice accumulate vacuoles throughout the brain that appear very similar to those associated with prion disease, but they do not accumulate the protease-resistant scrapie form of the prion protein or become sick.
Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein.
GeneRIF
Leibel et al., New York City, United States. In J Biol Chem, 2011
the md and mg mutations rescue the A(y) phenotypes by a primarily cAMP-independent mechanism promoting trafficking of MC4R and likely MC1R away from the lysosome toward the cell surface.
Dipeptidyl-peptidase 4 and attractin expression is increased in circulating blood monocytes of obese human subjects.
GeneRIF
Krone et al., Köln, Germany. In Exp Clin Endocrinol Diabetes, 2010
The levels of both dipeptidyl-peptidase 4 and attractin in circulating monocytes were significantly higher in obese subjects as compared with levels in lean controls or in subjects with type 2 diabetes.
Shades of meaning: the pigment-type switching system as a tool for discovery.
Review
Gunn et al., Great Falls, United States. In Pigment Cell Melanoma Res, 2010
In conjunction with the accessory proteins attractin and mahogunin ring finger 1, endogenous agonists and antagonists modulate signaling by the melanocortin 1 receptor to determine pigment type.
Abnormal myelinogenesis both in the white and gray matter of the attractin-deficient mv rat.
GeneRIF
Kuwamura et al., Ōsaka, Japan. In Brain Res, 2010
This study indicated that myelinogenesis but not oligodendrogenesis is severely altered both in the white and gray matter of attractin-deficient mv rats.
Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway.
GeneRIF
Bennett et al., London, United Kingdom. In Pigment Cell Melanoma Res, 2009
study shows ASIP-MC1R signaling includes a cAMP-independent pathway through attractin and mahogunin, while the known cAMP-dependent component requires neither attractin nor mahogunin
Novel partners of SPAG11B isoform D in the human male reproductive tract.
GeneRIF
French et al., Chapel Hill, United States. In Biol Reprod, 2009
associated with spermatozoa
Biology of epidermal and hair pigmentation in cattle: a mini-review.
Review
Hwang et al., Ch'ŏnan, South Korea. In Vet Dermatol, 2007
The switching between the syntheses of melanin components depends on several genes like melanocortin-1receptor gene (MC1r) - also known as melanocyte-stimulating hormone receptor gene (MSHr)-, agouti (A), attractin (Atrn) and mahogunin (Mgrn1).
Newly identified water-borne protein pheromones interact with attractin to stimulate mate attraction in Aplysia.
Review
Nagle et al., Galveston, United States. In Peptides, 2006
The water-borne protein attractin is a potent sex pheromone involved in forming and maintaining mating and egg-laying aggregations in the marine mollusk Aplysia.
Molluscan attractins, a family of water-borne protein pheromones with interspecific attractiveness.
Review
Nagle et al., Galveston, United States. In Peptides, 2005
The marine mollusk Aplysia releases the water-borne pheromone attractin during egg laying.
The intricate interface between immune system and metabolism.
Review
La Cava et al., Napoli, Italy. In Trends Immunol, 2004
Particular focus has been on certain cytokines [interleukin-1 (IL-1), IL-6, tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma)], hormones (leptin and insulin), neuropeptides (corticotropin-releasing hormone and alpha-melanocyte-stimulating hormone), immune-related proteins (zinc-alpha2-glycoprotein and attractin and/or mahogany), transcription factors (peroxisome-proliferator-activated receptors) and glucose metabolism.
Spongiform degeneration in mahoganoid mutant mice.
Impact
Gunn et al., Stanford, United States. In Science, 2003
mahoganoid is a mouse coat-color mutation whose pigmentary phenotype and genetic interactions resemble those of Attractin (Atrn).
A biochemical function for attractin in agouti-induced pigmentation and obesity.
Impact
Barsh et al., Stanford, United States. In Nat Genet, 2001
Mouse attractin (Atrn) is a widely expressed transmembrane protein whose loss of function in mahogany (Atrn(mg-3J)/ Atrn(mg-3J)) mutant mice blocks the pleiotropic effects of A(y).
The mouse mahogany locus encodes a transmembrane form of human attractin.
Impact
GeneRIF
Barsh et al., Stanford, United States. In Nature, 1999
The product of the murine "Mahogany" locus, controlling agouti-mediated melanocyte pigmentation and control of energy metabolism, is the murine ortholog of human attractin.
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