gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ATP11 Atp11p

Atp11p, ATP11
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: ATPase, Atp12p, CAN, ACID, Insulin
Papers on Atp11p
Identification of ATPAF1 as a novel candidate gene for asthma in children.
GeneRIF
Wills-Karp et al., East Lansing, United States. In J Allergy Clin Immunol, 2011
Asthma was found to be associated with a cluster of SNPs and SNP haplotypes containing the ATPAF1 gene
F1-dependent translation of mitochondrially encoded Atp6p and Atp8p subunits of yeast ATP synthase.
Tzagoloff et al., New York City, United States. In Proc Natl Acad Sci U S A, 2009
Mutants lacking the alpha or beta subunits of F(1), or the Atp11p and Atp12p chaperones that promote F(1) assembly, have normal levels of the bicistronic ATP8/ATP6 mRNAs but fail to synthesize Atp6p and Atp8p.
Chaperones of F1-ATPase.
Ackerman et al., Detroit, United States. In J Biol Chem, 2009
The assembly of this structure requires two specialized chaperones, Atp11p and Atp12p, that bind transiently to beta and alpha.
Assembly factors of F1FO-ATP synthase across genomes.
Houstek et al., Praha, Czech Republic. In Proteins, 2005
Work with respiration-deficient strains of Saccharomyces cerevisiae has provided evidence that assembly of the mitochondrial ATP synthase is dependent on proteins that serve substrate-specific, chaperone-type functions: Atp10p, Atp11p, Atp12p, Atp22p, and Fmc1p.
Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12.
Van Coster et al., Brussels, Belgium. In J Med Genet, 2004
Mutation analysis of the complete coding regions at the cDNA level of the nuclear ATP11, ATP12, ATPalpha, ATPbeta and ATPgamma genes and the mitochondrial MTATP6 and MTAT8 genes was undertaken in two unrelated patients.
Differential expression of ATPAF1 and ATPAF2 genes encoding F(1)-ATPase assembly proteins in mouse tissues.
Houstek et al., Praha, Czech Republic. In Febs Lett, 2003
Atp11p (Atpaf1p; F(1)-ATPase assembly factor 1) and Atp12p (Atpaf2p; F(1)-ATPase assembly factor 2) are proteins required for the assembly of beta (F(1)-beta) and alpha (F(1)-alpha) subunits into the mitochondrial ATPase.
A purified subfragment of yeast Atp11p retains full molecular chaperone activity.
Ackerman et al., Detroit, United States. In J Biol Chem, 2003
Atp11p is a molecular chaperone of the mitochondrial matrix that participates in the biogenesis pathway to form F1, the catalytic unit of the ATP synthase.
Atp11p and Atp12p are chaperones for F(1)-ATPase biogenesis in mitochondria.
Ackerman, Detroit, United States. In Biochim Biophys Acta, 2002
Our work, which employs the yeast Saccharomyces cerevisiae as a model system for studies of mitochondrial function, has provided evidence that assembly of the mitochondrial alpha and beta subunits into the F(1) oligomer requires two molecular chaperone proteins called Atp11p and Atp12p.
An accessible hydrophobic surface is a key element of the molecular chaperone action of Atp11p.
Ackerman et al., Detroit, United States. In J Biol Chem, 2001
Atp11p is a soluble protein of mitochondria that binds unassembled beta subunits of the F(1)-ATPase and prevents them from aggregating in the matrix.
Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria.
Ackerman et al., Detroit, United States. In J Biol Chem, 2001
Atp11p and Atp12p were first described as proteins required for assembly of the F(1) component of the mitochondrial ATP synthase in Saccharomyces cerevisiae (Ackerman, S. H., and Tzagoloff, A. (1990) Proc.
Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions.
di Rago et al., Bordeaux, France. In J Biol Chem, 2001
Identical perturbations were reported previously for yeast cells lacking either Atp12p or Atp11p, two specific assembly factors of the F(1) sector (Ackerman, S. H., and Tzagoloff, A. (1990) Proc.
The assembly factor Atp11p binds to the beta-subunit of the mitochondrial F(1)-ATPase.
Ackerman et al., Detroit, United States. In J Biol Chem, 2000
Atp11p is a protein of Saccharomyces cerevisiae required for the assembly of the F(1) component of the mitochondrial F(1)F(0)-ATP synthase.
The Drosophila gene 2A5 complements the defect in mitochondrial F1-ATPase assembly in yeast lacking the molecular chaperone Atp11p.
Ackerman et al., Detroit, United States. In Febs Lett, 1999
A cDNA encoding the putative Atp11p from Drosophila yakuba was shown to complement the respiratory deficient phenotype of yeast harboring an atp11::HIS3 disruption allele.
Epistatic interactions of deletion mutants in the genes encoding the F1-ATPase in yeast Saccharomyces cerevisiae.
Mueller et al., North Chicago, United States. In Embo J, 1999
These results indicate that epsilon is not an essential component of the ATP synthase and that mutations in the genes encoding the alpha- and beta-subunits and in ATP11 are epistatic to null mutations in the genes encoding the gamma- and delta-subunits.
Identification of functional domains in Atp11p. Protein required for assembly of the mitochondrial F1-ATPase in yeast.
Ackerman et al., Detroit, United States. In J Biol Chem, 1996
The mutant atp11 genes were cloned and sequenced from 12 yeast strains, which are respiratory-deficient due to a defect in Atp11p function.
share on facebooktweetadd +1mail to friends