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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Activating transcription factor 7

ATF7, Transcription factor ATF, Transcription factor ATF-2
Top mentioned proteins: GDNF, AP-1, CAN, TBP, Npl3
Papers on ATF7
CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.
New
Thome et al., Lausanne, Switzerland. In Blood, Feb 2016
In contrast to germinal center B-cell (GCB) DLBCL, ABC DLBCL cell lines expressed high levels of the AP-1 family members c-Jun, JunB and JunD, which formed heterodimeric complexes with the AP-1 family members ATF2, ATF3 and ATF7.
The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.
New
Impact
Ishii et al., Tsukuba, Japan. In Nat Immunol, Oct 2015
Here we identified an important role for the stress-response transcription factor ATF7 in innate immunological memory.
Expression of activating transcription factor 7 is correlated with prognosis of colorectal cancer.
New
Yang et al., Zhengzhou, China. In J Cancer Res Ther, Apr 2015
In our study, we investigated the clinical and prognostic role of activating transcription factor 7 (ATF7) in CRC.
A humanized leucine zipper-TRAIL hybrid induces apoptosis of tumors both in vitro and in vivo.
Strongin et al., Sioux Falls, United States. In Plos One, 2014
Here, we report a novel, potent, and fully human ATF7 leucine zipper-TRAIL (ATF7-TRAIL) fusion construct that is expected to have substantially lower immunogenicity.
ATF7 is stabilized during mitosis in a CDK1-dependent manner and contributes to cyclin D1 expression.
Donzeau et al., Illkirch-Graffenstaden, France. In Cell Cycle, 2014
The transcription factor ATF7 undergoes multiple post-translational modifications, each of which has distinct effects upon ATF7 function.
The JNK1/JNK3 interactome--contributions by the JNK3 unique N-terminus and JNK common docking site residues.
Bogoyevitch et al., Melbourne, Australia. In Biochem Biophys Res Commun, 2014
ΔN JNK3α1), and interaction evaluation in the yeast two-hybrid system defined the interacting partners as either JNK1-specific interactors (ATF7, FUS, KCNE4, PIAS1, SHANK1, TKT), typical JBD-dependent interactors shared by JNK1α1 and JNK3α1 (AKAP6, BMPR2, EEF1A1, GFAP, GRIP2, GTF2F1, HDAC2, MAP1B, MYO9B, PTPN2, RABGAP1, RUSC2, SUMO1, SYPL1, TOPBP1, ZNF668), or JNK3-specific partners (ATXN1, NNAT, PTGDS) dependent on interaction with the JNK3 N-terminal extension.
Sensitisation of c-MYC-induced B-lymphoma cells to apoptosis by ATF2.
Breitwieser et al., Manchester, United Kingdom. In Oncogene, 2014
Transcription factors ATF2 (activating transcription factor 2) and ATF7 (activating transcription factor 7) are highly homologous members of the activator protein 1 (AP-1) family.
TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.
Galson et al., Pittsburgh, United States. In J Bone Miner Res, 2014
TBK1 overexpression induced IL6 promoter reporter activity, and elevated endogenous IL6 mRNA and p65 NF-κB, TAF12, and ATF7 proteins in several cell lines.
Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase.
Yamaguchi et al., Chiba, Japan. In Plos One, 2013
Activating transcription factor 2 (ATF2) and its homolog ATF7 are phosphorylated at Thr-69/Thr-71 and at Thr-51/Thr-53, respectively, by stress-activated MAPKs regulating their transcriptional functions in G1 and S phases.
Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease.
Kurihara et al., Indianapolis, United States. In J Bone Miner Res, 2013
Because TAF12 directly interacts with the cyclic adenosine monophosphate-dependent activating transcription factor 7 (ATF7) and potentiates ATF7-induced transcriptional activation of ATF7-driven genes in other cell types, we determined whether TAF12 is a functional partner of ATF7 in OCL precursors.
Transcription factor ATF-3 regulates allele variation phenotypes of the human SLC11A1 gene.
Anagnou et al., Athens, Greece. In Mol Biol Rep, 2013
Genetic polymorphisms in the human solute carrier family 11 member 1 (SLC11A1) gene predispose to susceptibility to infectious/inflammatory diseases and cancer.
The roles of ATF2 (activating transcription factor 2) in tumorigenesis.
Review
Breitwieser et al., Manchester, United Kingdom. In Biochem Soc Trans, 2012
The aim of the present review is to provide an overview of the functions of two ATF family proteins, ATF2 and ATF7, in mammalian development and their potential functions in tumour formation.
A cytoplasmic negative regulator isoform of ATF7 impairs ATF7 and ATF2 phosphorylation and transcriptional activity.
GeneRIF
Chatton et al., Illkirch-Graffenstaden, France. In Plos One, 2010
Data show that ATF7-4 is an important cytoplasmic negative regulator of ATF7 and ATF2 transcription factors.
p38beta2-mediated phosphorylation and sumoylation of ATF7 are mutually exclusive.
GeneRIF
Chatton et al., Illkirch-Graffenstaden, France. In J Mol Biol, 2009
The authors characterized the multisite phosphorylation of the ATF7 activation domain and identified one of the involved kinase, p38beta2 mitogen-activated protein kinase.
New insights into TAFs as regulators of cell cycle and signaling pathways.
Review
Mengus et al., France. In Cell Cycle, 2005
TAF4 is however essential in the retinoic acid and cAMP signalling pathways acting as a cofactor for CREB and the retinoic acid receptor, but is a negative regulator of the ATF7 transcription factor.
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex.
Impact
Roeder et al., New York City, United States. In Cell, 1988
The mammalian activator protein ATF stimulates transcription from the adenovirus E4 promoter by binding to multiple upstream promoter and enhancer elements.
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