Ataxia telangiectasia mutated
Agrobacterium T-DNA integration into the plant genome can occur without the activity of key non-homologous end-joining proteins.
West Lafayette, United States. In Plant J, Mar 2015
In animal cells, several proteins, including KU70, KU80, ARTEMIS, DNA-PKcs, DNA ligase IV (LIG4), Ataxia telangiectasia mutated (ATM), and ATM- and Rad3-related (ATR), play an important role in 'classical' (c)NHEJ.
The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60.
Augusta, United States. In Nat Commun, 2014
Tat-interactive protein 60 (Tip60) is a MYST histone acetyltransferase that catalyses acetylation of the major DNA damage kinase Ataxia telangiectasia mutated (ATM), thereby triggering cellular signalling required for the maintenance of genomic stability on genotoxic insults.