Hereditary diffuse gastric cancer: What the clinician should know.
Singapore, Singapore. In World J Gastrointest Oncol, Oct 2015
Recent findings of other gene defects in CTNNA1 and MAP3K6, as well as further characterization of CDH1 mutations and their pathogenicity will change the way HDGC patients are counselled for screening, surveillance and treatment.
Recognition of and recent issues in hereditary diffuse gastric cancer.
Tokyo, Japan. In J Gastroenterol, Aug 2015
Because of these advances, searches for candidate genes (e.g., CTNNA1, MAP3K6) and our understanding of HDGC pathogenesis have improved in recent years; moreover, there have been substantial changes in the field since the current HDGC consensus guidelines were released.
ASK family proteins in stress response and disease.
Tokyo, Japan. In Mol Biotechnol, 2007
Here, we highlight the roles of members of the ASK family, which consists of ASK1 and newly characterized ASK2, in ROS signaling with their possible involvement in human diseases.