gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Angiopoietin-like 2

Arp2
Top mentioned proteins: Actin, Wasp, N-WASP, CAN, V1a
Papers using Arp2 antibodies
The ‘ins’ and ‘outs’ of podosomes and invadopodia: characteristics, formation and function.
Supplier
Stradal Theresia E. B., In PLoS ONE, 2010
... (Heidelberg, Germany), against vinculin from Synaptic Systems (Göttingen, Germany) and Sigma-Aldrich (Hamburg, Germany), and against Arp2 from Abcam (Cambridge, UK) ...
Papers on Arp2
Impact of genetic variation on synaptic protein levels in genetically diverse mice.
New
Spijker et al., Amsterdam, Netherlands. In Proteomics, Feb 2016
Analysis of protein abundance covariation across the 8 strains identified known protein-protein relations (proteins of Arp2/3 complex), as well as novel relations (e.g., Dlg family, Fscn1).
Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks.
New
Impact
Mullins et al., San Francisco, United States. In Cell, Feb 2016
Branched actin networks-created by the Arp2/3 complex, capping protein, and a nucleation promoting factor-generate and transmit forces required for many cellular processes, but their response to force is poorly understood.
Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.
New
Italiano et al., Boston, United States. In Blood, Feb 2016
We hypothesized that MARCKS phosphorylation promotes Arp2/3 phosphorylation through PIP2 signaling, which subsequently downregulates proplatelet formation.
Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.
New
Cherfils et al., Cachan, France. In Structure, Feb 2016
UNASSIGNED: Arpin is a newly discovered regulator of actin polymerization at the cell leading edge, which steers cell migration by exerting a negative control on the Arp2/3 complex.
Isoform diversity in the Arp2/3 complex determines actin filament dynamics.
New
Impact
Way et al., Gif-sur-Yvette, France. In Nat Cell Biol, Jan 2016
The Arp2/3 complex consists of seven evolutionarily conserved subunits (Arp2, Arp3 and ARPC1-5) and plays an essential role in generating branched actin filament networks during many different cellular processes.
Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells.
New
Impact
Lennon-Duménil et al., France. In Nat Cell Biol, Jan 2016
Here, we show that the migration of immature DCs depends on two main actin pools: a RhoA-mDia1-dependent actin pool located at their rear, which facilitates forward locomotion; and a Cdc42-Arp2/3-dependent actin pool present at their front, which limits migration but promotes antigen capture.
The centrosome is an actin-organizing centre.
New
Impact
Théry et al., Grenoble, France. In Nat Cell Biol, Jan 2016
Actin-filament nucleation at the centrosome was mediated by the nucleation-promoting factor WASH in combination with the Arp2/3 complex.
Comprehensive proteomic and metabolomic signatures of nontypeable Haemophilus influenzae-induced acute otitis media reveal bacterial aerobic respiration in an immunosuppressed environment.
New
Mason et al., United States. In Mol Cell Proteomics, Jan 2016
We validated the observed increase in the actin-remodeling complex, Arp2/3 and experimentally demonstrated a role for Arp2/3 in NTHI invasion.
Formins at the Junction.
Review
New
Grosse et al., Marburg an der Lahn, Germany. In Trends Biochem Sci, Jan 2016
The actin regulatory complex Arp2/3 has an established role in the turnover of junctional actin; however, the role of formins, the largest group of actin regulators, is less clear.
How distinct Arp2/3 complex variants regulate actin filament assembly.
New
Impact
Stradal et al., Braunschweig, Germany. In Nat Cell Biol, Jan 2016
The heptameric Arp2/3 complex generates branched actin filament networks that drive lamellipodium protrusion, vesicle trafficking and pathogen motility.
The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons.
New
Torre et al., Trieste, Italy. In Plos One, Dec 2015
Inhibition of Arp2/3 by a moderate amount of the drug CK-548 caused a transient retraction of lamellipodia followed by a complete recovery of their usual motility.
Viruses that ride on the coat-tails of actin nucleation.
Review
New
Marzook et al., Sydney, Australia. In Semin Cell Dev Biol, Oct 2015
Vaccinia virus and baculovirus, Autographa californica multiple nucleopolyhedrovirus, recruit and activate the cellular actin nucleator, the Arp2/3 complex, at the surface of virus particles thereby instigating highly localized actin nucleation.
Signaling networks that regulate cell migration.
Review
New
Horwitz et al., Charlottesville, United States. In Cold Spring Harb Perspect Biol, Aug 2015
Their effectors include actin regulators such as formins, members of the WASP/WAVE family and the Arp2/3 complex, and the myosin II motor protein.
Drosophila comes of age as a model system for understanding the function of cytoskeletal proteins in cells, tissues, and organisms.
Review
New
Martin et al., Cambridge, United States. In Cytoskeleton (hoboken), May 2015
In this review, written for non-Drosophila experts, we will discuss critical technical advances that have enabled these cell biological insights, highlighting three examples of cytoskeletal discoveries that have arisen as a result: (1) regulation of Arp2/3 complex in myoblast fusion, (2) cooperation of the actin filament nucleators Spire and Cappuccino in establishment of oocyte polarity, and (3) coordination of supracellular myosin cables.
VEGF Signaling Regulates Cofilin and the Arp2/3-complex within the Axonal Growth Cone.
Review
Theiss et al., Bochum, Germany. In Curr Neurovasc Res, 2014
Overall, we describe the role of VEGF regulation of cofilin and the Arp2/3-complex in axonal growth cones.
Macrophage-derived angiopoietin-like protein 2 accelerates development of abdominal aortic aneurysm.
GeneRIF
Oike et al., Kumamoto, Japan. In Arterioscler Thromb Vasc Biol, 2012
Macrophage-derived Angptl2 contributes to abdominal aortic aneurysm development by inducing inflammation and degradation of extracellular matrix in the vessel wall.
Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.
GeneRIF
Elias et al., New Haven, United States. In Am J Respir Cell Mol Biol, 2012
demonstrate the ability of NOS2 to inhibit hyperoxia-induced Ang2 production and thereby decrease Ang2-induced tissue injury
Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis.
GeneRIF
Oike et al., Kumamoto, Japan. In Cancer Res, 2012
tumor cell-derived ANGPTL2 drives metastasis and provided an initial proof of concept for blockade of its action as a strategy to antagonize the metastatic process.
The role of angiopoietin-like protein 2 in pathogenesis of dermatomyositis.
GeneRIF
Oike et al., Kumamoto, Japan. In Biochem Biophys Res Commun, 2012
keratinocyte-derived Angptl2 functions in dermatomyositis pathogenesis by inducing chronic inflammation in skin tissue.
Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis.
GeneRIF
Oike et al., Kumamoto, Japan. In Cancer Res, 2012
Data suggest that angiopoietin-like protein 2 (Angptl2) contributes to increased carcinogenesis and metastasis and represents a novel target to antagonize these pathologies.
share on facebooktweetadd +1mail to friends