Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion.
Lund, Sweden. In Mol Biosyst, 2011
Here, the cellular interaction network of secretagogin has been expanded with nine proteins: SNAP-23, DOC2alpha, ARFGAP2, rootletin, KIF5B, β-tubulin, DDAH-2, ATP-synthase and myeloid leukemia factor 2, based on screening of a high content protein array and validation and quantification of binding with surface plasmon resonance and GST pulldown assays.
Arf GAPs: gatekeepers of vesicle generation.
Basel, Switzerland. In Febs Lett, 2010
In this review, we will focus mainly on the Arf GAPs that play a role in vesicle formation, Arf GAP1, Arf GAP2 and Arf GAP3 and their yeast homologues, Gcs1p and Glo3p.