The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation
In The Journal of Cell Biology, 1999
... obtained from Sigma-Aldrich, phalloidin-rhodamine from Invitrogen, anti-pericentrin from BabCO, anti-GM130, anti-EEA1, and anti-Rac1 from BD, anti-Arf6 from AbCam, anti-Cdc42, anti-Par6, and anti-PKCζ ...
Excessive Selenium Supplementation Induced Oxidative Stress and Endoplasmic Reticulum Stress in Chicken Spleen.
Mianyang, China. In Biol Trace Elem Res, Feb 2016
Then, the levels of antioxidative enzymes, GPx, SOD, and MDA as well as the expression levels of GRP78, ARF6, caspase 3, caspase 12, and Bcl 2 in the spleen were determined at days 15, 30, and 45, respectively.
Genome-wide association studies in biliary atresia.
Pittsburgh, United States. In Wiley Interdiscip Rev Syst Biol Med, Sep 2015
Although distinct, these susceptibility genes share several functions including roles in mechanisms for organogenesis (glypican 1 or GPC1, and adenosine diphosphate ribosylation factor 6, or ARF6) or a greater expression in fetal liver than in adult liver (adducin 3 or ADD3).
Rab-mediated trafficking role in neurite formation.
Santiago, Chile. In J Neurochem, 2014
Finally, we also discuss the participation of the ADP-ribosylation factor 6, a member of the ArfGTPase family, in neurite formation since it seems to have an important cross-talk with RabGTPases.
Activation machinery of the small GTPase Arf6.
Tsukuba, Japan. In Adv Biol Regul, 2014
The small GTPase ADP-ribosylation factor 6 (Arf6) plays pivotal roles in a wide variety of cellular events, including exocytosis, endocytosis, actin cytoskeleton reorganization and phosphoinositide metabolism, in various types of cells.
Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.
Salt Lake City, United States. In Nature, 2013
Here we show that the direct, immediate and disruptive effects of IL-1β on endothelial stability in a human in vitro cell model are NF-κB independent and are instead the result of signalling through the small GTPase ADP-ribosylation factor 6 (ARF6) and its activator ARF nucleotide binding site opener (ARNO; also known as CYTH2).
Mechanisms of endocytosis.
Cambridge, United Kingdom. In Annu Rev Biochem, 2008
These clathrin-independent pathways include the CLIC/GEEC endocytic pathway, arf6-dependent endocytosis, flotillin-dependent endocytosis, macropinocytosis, circular doral ruffles, phagocytosis, and trans-endocytosis.
ARF proteins: roles in membrane traffic and beyond.
United States. In Nat Rev Mol Cell Biol, 2006
Recent advances in our understanding of the signalling pathways that are regulated by ARF1 and ARF6, two of the best characterized ARF proteins, provide a molecular context for ARF protein function in fundamental biological processes, such as secretion, endocytosis, phagocytosis, cytokinesis, cell adhesion and tumour-cell invasion.