Physiological roles of aquaporin-4 in brain.
In Physiol Rev, 2013
Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces.
Aquaporin water channels in the nervous system.
London, United Kingdom. In Nat Rev Neurosci, 2013
AQP1 is expressed in the choroid plexus, where it facilitates cerebrospinal fluid secretion, and in dorsal root ganglion neurons, where it tunes pain perception.
Aquaporin 4 and neuromyelitis optica.
London, United Kingdom. In Lancet Neurol, 2012
The discovery of circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) and the evidence that AQP4-IgG is involved in the development of neuromyelitis optica revolutionised our understanding of the disease.