Hepatocyte aquaporins in bile formation and cholestasis.
Rosario, Argentina. In Front Biosci, 2010
Aquaporin-8 (AQP8), localized to canalicular membranes, modulates membrane water permeability providing a molecular mechanism for the osmotically-coupled transport of solute and water during bile formation.
Aquaporins in the kidney: from molecules to medicine.
Århus, Denmark. In Physiol Rev, 2002
AQP6 is present in intracellular vesicles in collecting duct intercalated cells, and AQP8 is present intracellularly at low abundance in proximal tubules and collecting duct principal cells, but the physiological function of these two channels remains undefined.