GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 14 Mar 2013.
Apolipoprotein Ea
apolipoprotein E
Sponsored links
Papers on
apolipoprotein E
Neuronal fiber bundle lengths in healthy adult carriers of the ApoE4 allele: A quantitative tractography DTI study.
New
Saint Louis, United States. In Brain Imaging Behav, 10 Apr 2013
The epsilon 4 (e4) isoform of apolipoprotein E (ApoE) is a known genetic risk factor for suboptimal brain health.
Tumour expression of bladder cancer-associated urinary proteins.
New
Uppsala, Sweden. In Bju Int, 07 Apr 2013
The proteins apolipoprotein E (APOE), fibrinogen β chain precursor (FGB), leucine-rich α2-glycoprotein (LRG1), polymerase (RNA) I polypeptide E (POLR1E), α1-antitrypsin (SERPINA1) and topoisomerase 2A (TOP2A) were probed with antibodies validated by the Human Protein Atlas.
Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old.
New
Denver, United States. In Alzheimers Dement, 06 Apr 2013
OBJECTIVE: Apolipoprotein E (APOE) ε2 carriers may be protected from dementia because of reduced levels of cortical β-amyloid.
Variant of TREM2 associated with the risk of Alzheimer's disease.
New
Impact
Reykjavík, Iceland. In N Engl J Med, 10 Feb 2013
BACKGROUND: Sequence variants, including the ε4 allele of apolipoprotein E, have been associated with the risk of the common late-onset form of Alzheimer's disease.
Preclinical sporadic Alzheimer's disease: target for personalized diagnosis and preventive intervention.
Review
New
New York City, United States. In Metabolism, Jan 2013
This review focuses on the genetic biomarker, apolipoprotein E (apoE) ε4, and on certain neuroimaging biomarkers, such as structural MRI (sMRI), fluorodeoxyglucose-positron emission tomography (FDG-PET), and PET-amyloid tracers capable of delineating the extent and distribution of amyloid-beta (Aβ) deposits in the brain, that can be useful in identifying cognitively normal people who are at enhanced risk of developing spAD.
[Connections between apolipoprotein E genotypes and the development of cardiovascular diseases].
Review
New
Budapest, Hungary. In Orv Hetil, Jan 2013
Apolipoprotein E plays a part in the lipid transport in the blood, thus polimophisms of that affect the lipid composition of the plasma.
Differentiated miRNA expression and validation of signaling pathways in apoE gene knockout mice by cross-verification microarray platform.
New
Harbin, China. In Exp Mol Med, Dec 2012
Microarray analysis was then simultaneously performed on pooled atherosclerotic aortic tissues from 10 Apolipoprotein E (apoE) knockout mice (apoE-/-) and 10 healthy C57BL/6 (B6) mice.
Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.
New
Impact
Phoenix, United States. In Lancet Neurol, Dec 2012
The carrier and non-carrier groups did not differ significantly in their dementia ratings, neuropsychological test scores, or proportion of apolipoprotein E (APOE) ɛ4 carriers.
Roles of Apolipoprotein E (ApoE) and Inducible Nitric Oxide Synthase (iNOS) in Inflammation and Apoptosis in Preeclampsia Pathogenesis and Progression.
New
Shanghai, China. In Plos One, Dec 2012
OBJECTIVE: To investigate potential roles of inducible nitric oxide synthase (iNOS) and apolipoprotein (apoE) in inflammation and apoptosis promoting pathological changes in preeclampsia in pregnant mice with apoE and/or iNOS knock out.
Inflammatory Stress Exacerbates the Progression of Cardiac Fibrosis in High-Fat-Fed Apolipoprotein E Knockout Mice via Endothelial-Mesenchymal Transition.
New
Nanjing, China. In Int J Med Sci, Dec 2012
This study investigated whether inflammation exacerbated the progression of cardiac fibrosis in high-fat-fed apolipoprotein E knockout (ApoE KO) mice via endothelial-mesenchymal transition (EndMT).
Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis.
New
Impact
New York City, United States. In Cell, Dec 2012
These miRNAs convergently target apolipoprotein E (ApoE) and the heat shock factor DNAJA4.
Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis.
Review
New
New York City, United States. In Arterioscler Thromb Vasc Biol, Nov 2012
Studies in mice with defects in cholesterol efflux pathways have identified novel roles for the ATP-binding cassette transporter A1, ATP-binding cassette transporter G1, and apolipoprotein E in suppressing hematopoietic stem cell proliferation, mobilization, and the production of monocytes and neutrophils in the bone marrow.
Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer`s disease. A meta-analysis.
Review
New
Tabrīz, Iran. In Neurosciences (riyadh), Oct 2012
OBJECTIVE: To obtain a better insight into the effect of the epsilon (e) 4 allele of the apolipoprotein E gene (APOE) on the risk of late onset Alzheimer`s disease (LOAD), and assess its heterogeneity in geographic regions.
Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales.
Review
New
Impact
Canberra, Australia. In Pharmacol Rev, Oct 2012
We argue here that a number of independently developing approaches to therapy-including specific and nonspecific anti-tumor necrosis factor (TNF) agents, apolipoprotein E mimetics, leptin, intranasal insulin, the glucagon-like peptide-1 mimetics and glycogen synthase kinase-3 (GSK-3) antagonists-are all part of an interlocking chain of events.
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.
New
Impact
Rochester, United States. In Nature, Jun 2012
Human apolipoprotein E has three isoforms: APOE2, APOE3 and APOE4.
