Tumour expression of bladder cancer-associated urinary proteins.
Uppsala, Sweden. In Bju Int, 07 Apr 2013
The proteins apolipoprotein E (APOE), fibrinogen β chain precursor (FGB), leucine-rich α2-glycoprotein (LRG1), polymerase (RNA) I polypeptide E (POLR1E), α1-antitrypsin (SERPINA1) and topoisomerase 2A (TOP2A) were probed with antibodies validated by the Human Protein Atlas.
Preclinical sporadic Alzheimer's disease: target for personalized diagnosis and preventive intervention.
New York City, United States. In Metabolism, Jan 2013
This review focuses on the genetic biomarker, apolipoprotein E (apoE) ε4, and on certain neuroimaging biomarkers, such as structural MRI (sMRI), fluorodeoxyglucose-positron emission tomography (FDG-PET), and PET-amyloid tracers capable of delineating the extent and distribution of amyloid-beta (Aβ) deposits in the brain, that can be useful in identifying cognitively normal people who are at enhanced risk of developing spAD.
Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis.
New York City, United States. In Arterioscler Thromb Vasc Biol, Nov 2012
Studies in mice with defects in cholesterol efflux pathways have identified novel roles for the ATP-binding cassette transporter A1, ATP-binding cassette transporter G1, and apolipoprotein E in suppressing hematopoietic stem cell proliferation, mobilization, and the production of monocytes and neutrophils in the bone marrow.