Genetics of psychosis of Alzheimer disease.
Pittsburgh, United States. In Am J Med Genet B Neuropsychiatr Genet, Feb 2016
Association studies examining apolipoprotein E gene, the best established genetic risk factor for late-onset AD, did not find any significant association of this gene with AD+P.
Statins for the prevention of dementia.
Antrim, United Kingdom. In Cochrane Database Syst Rev, Feb 2016
OBJECTIVES: To evaluate the efficacy and safety of statins for the prevention of dementia in people at risk of dementia due to their age and to determine whether the efficacy and safety of statins for this purpose depends on cholesterol level, apolipoprotein E (ApoE) genotype or cognitive level.
Genetic risk factors for spontaneous intracerebral haemorrhage.
United States. In Nat Rev Neurol, Jan 2016
Two variants of the gene encoding apolipoprotein E (APOE) - which also contributes to the pathogenesis of cerebral amyloid angiopathy - are the most likely candidates for variants that increase the risk of ICH.