Physiological regulation of lipoprotein lipase.
Wageningen, Netherlands. In Biochim Biophys Acta, Jul 2014
These proteins can be divided into two main groups: the liver-derived apolipoproteins APOC1, APOC2, APOC3, APOA5, and APOE, and the angiopoietin-like proteins ANGPTL3, ANGPTL4 and ANGPTL8, which have a broader expression profile.
Genetic loci associated with changes in lipid levels leading to constitution-based discrepancy in Koreans.
Taejŏn, South Korea. In Bmc Complement Altern Med, Dec 2013
By analyzing TE and non-TE type (each 2,664 subjects) populations classified on the basis of Sasang constitutional medicine, we found that the minor allele effects of three variants enriched in TE type had a harmful influence on lipid risk (near apolipoprotein A-V (APOA5)-APOA4-APOC3-APOA1 on increased triglyceride: p = 8.90 × 10(-11), in APOE-APOC1-APOC4 on increased low-density lipoprotein cholesterol: p = 1.63 × 10(-5), and near endothelial lipase gene on decreased high-density lipoprotein cholesterol: p = 4.28 × 10(-3)), whereas those of three variants (near angiopoietin-like 3 gene, APOA5-APOA4-APOC3-APOA1, and near lipoprotein lipase gene on triglyceride and high-density lipoprotein cholesterol) associated in non-TE type had neutral influences because of a compensating effect.
Dyslipidemia in women with polycystic ovary syndrome.
Seoul, South Korea. In Obstet Gynecol Sci, May 2013
Some studies have investigated apolipoprotein (Apo) A-I and ApoC-I levels in women with PCOS and levels of ApoA-I, which has cardio-protective effects, were significantly lower in women with PCOS than those of controls.
Dyslipidemia in PCOS.
Oklahoma City, United States. In Steroids, 2012
They have higher ApoCIII/ApoCII ratios and higher ApoCI even if they are not obese.
APOE and cholesterol homeostasis in Alzheimer's disease.
Montréal, Canada. In Trends Mol Med, 2010
These associations include the recognition of cholesterol transporters apolipoprotein E (APOE), APOC1 and APOJ as major genetic risk factors for common AD and observations associating risk factors for cardiovascular disease such as high midlife plasma cholesterol, diabetes, stroke, obesity and hypertension to dementia.