GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 14 Mar 2013.
Apolipoprotein A-Ia
apolipoprotein A-I, apoA-I
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Papers on
apolipoprotein A-I
Discoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle.
New
Lund, Sweden. In J Lipid Res, 07 Apr 2013
Lipid-free apoA-I and mature spherical HDL have been shown to induce glucose uptake in skeletal muscle.
Apolipoprotein A-I Helsinki promotes intracellular acyl-CoA cholesterol acyltransferase (ACAT) protein accumulation.
New
La Plata, Argentina. In Mol Cell Biochem, 03 Apr 2013
Reverse cholesterol transport is a process of high antiatherogenic relevance in which apolipoprotein AI (apoA-I) plays an important role.
Apolipoprotein A-I binding to anionic vesicles and lipopolysaccharides: role for lysine residues in antimicrobial properties.
New
Long Beach, United States. In Biochim Biophys Acta, 26 Mar 2013
Human apolipoprotein A-I (apoA-I) is a 28kDa protein and a major component of high-density lipoproteins, mediating several essential metabolic functions related to heart disease.
Apolipoprotein A-I mimetic peptide reverse D-4F improves the biological functions of mouse bone marrow-derived late EPCs via PI3K/AKT/eNOS pathway.
New
China. In Mol Cell Biochem, 23 Mar 2013
Apolipoprotein A-I (ApoA-I) mimetic peptide inhibits the development of atherosclerosis (AS) in apolipoprotein E-deficient mice; however, the underlying mechanism remains unclear.
Increased Serum Cholesterol Esterification Rates Predict Coronary Heart Disease and Sudden Death in a General Population.
New
Toyooka, Japan. In Arterioscler Thromb Vasc Biol, 21 Mar 2013
Serum concentrations of apolipoprotein A-I, A-II, B, C-II, C-III, E, and LCAT activity measured as a serum cholesterol esterification rate were evaluated.
Proteomic biomarkers of type 2 diabetes mellitus risk in women with polycystic ovary syndrome.
Review
New
Nottingham, United Kingdom. In Eur J Endocrinol, 28 Feb 2013
These include pyruvate kinase M1/M2, apolipoprotein A-I, albumin, peroxiredoxin 2, annexin A2, α-1-B-glycoprotein, flotillin-1 and haptoglobin.
High-density lipoprotein function, dysfunction, and reverse cholesterol transport.
Review
New
New York City, United States. In Arterioscler Thromb Vasc Biol, Dec 2012
Raising HDL levels in animal models by infusion or overexpression of apolipoprotein A-I has shown clear vascular improvements, such as delayed atherosclerotic lesion progression and accelerated lesion regression, along with increased reverse cholesterol transport.
High density lipoprotein biogenesis, cholesterol efflux, and immune cell function.
Review
New
Winston-Salem, United States. In Arterioscler Thromb Vasc Biol, Nov 2012
This review provides a summary of recent research on the role of high-density lipoprotein (HDL)/apolipoprotein A-I cholesterol efflux and immune cell function.
High-density lipoprotein and 4F peptide reduce systemic inflammation by modulating intestinal oxidized lipid metabolism: novel hypotheses and review of literature.
Review
New
Los Angeles, United States. In Arterioscler Thromb Vasc Biol, Nov 2012
In vitro and in vivo normal high-density lipoprotein (HDL), normal apolipoprotein A-I, and apolipoprotein A-I mimetic peptides, each likely acting in a different manner, prevent the inflammatory reaction characteristic of atherosclerosis, and this is associated with decreased levels of oxidized lipids in tissues and cells.
Approach to the patient with extremely low HDL-cholesterol.
Review
New
Philadelphia, United States. In J Clin Endocrinol Metab, Oct 2012
Confirmation of HDL-C levels below 20 mg/dl in the absence of severe hypertriglyceridemia should be followed by evaluation for secondary causes, such as androgen use, malignancy, and primary monogenic disorders, namely, apolipoprotein A-I mutations, Tangier disease, and lecithin-cholesterol acyltransferase deficiency.
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival.
New
Impact
Tübingen, Germany. In Nat Med, Aug 2012
Furthermore, among six predefined populations of myeloid-derived suppressor cells, two were prognostic for overall survival, and among over 300 serum biomarkers, we identified apolipoprotein A-I (APOA1) and chemokine (C-C motif) ligand 17 (CCL17) as being predictive for both immune response to IMA901 and overall survival.
Lipid-related markers and cardiovascular disease prediction.
New
Impact
In Jama, Jul 2012
OBJECTIVE: To determine whether adding information on apolipoprotein B and apolipoprotein A-I, lipoprotein(a), or lipoprotein-associated phospholipase A2 to total cholesterol and high-density lipoprotein cholesterol (HDL-C) improves cardiovascular disease (CVD) risk prediction.
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis.
Impact
Philadelphia, United States. In N Engl J Med, 2011
RESULTS: The levels of HDL cholesterol and apolipoprotein A-I were significant determinants of cholesterol efflux capacity but accounted for less than 40% of the observed variation.
Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation.
Impact
United States. In Cell Metab, 2010
Apolipoprotein A-I (apoA-I), a serum apolipoprotein that induces antiatherogenic efflux of macrophage cholesterol, is widely described as anti-inflammatory because it neutralizes bacterial lipopolysaccharide.
Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk.
Review
Impact
Cambridge, United Kingdom. In Jama, 2008
and higher mean apolipoprotein A-I concentrations (2.4%; 95% CI, 1.6%-3.2%).
Rapid incorporation of functional rhodopsin into nanoscale apolipoprotein bound bilayer (NABB) particles.
GeneRIF
New York City, United States. In J Mol Biol, 2008
The NABB system using engineered zebrafish apo A-I is a native-like membrane mimetic system for G-protein-coupled receptors.
