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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 31 Oct 2014.

Apolipoprotein A-Ia

apolipoprotein A-I, apoA-I
Top mentioned proteins: HDL, Apo, HAD, CAN, fibrillin-1
Papers on apolipoprotein A-I
Minimum Amino Acid Residues of an α-Helical Peptide Leading to Lipid Nanodisc Formation.
Kitamoto et al., In J Oleo Sci, 30 Nov 2014
In order to identify the minimum number of amino acid residues of an amphiphilic α-helical peptide that leads to nanodisc formation, seven peptides differing in lengths (22-, 18-, 14-, 12-, 10-, 8-, and 6-mers) that mimic and modify the C-terminal domain of apoA-I (residues 220-241) were synthesized.
High-density lipoprotein and atherosclerosis: Roles of lipid transporters.
Saku et al., Fukuoka, Japan. In World J Cardiol, 26 Nov 2014
HDL therapies that use injections of reconstituted HDL, apoA-I mimetics, or full-length apoA-I have shown dramatic effectiveness.
Defective functionality of HDL particles in familial apolipoprotein A-I deficiency: relevance of alterations in HDL lipidome and proteome.
Kontush et al., São Paulo, Brazil. In J Lipid Res, 23 Nov 2014
Homozygotes displayed undetectable plasma levels of apoA-I and reduced levels of HDL-cholesterol and apoC-III (5.4% and 42.6% of controls, respectively).
Influence of dietary nicotinic acid supplementation on lipid metabolism and related gene expression in two distinct broiler breeds of female chickens.
Wen et al., In J Anim Physiol Anim Nutr (berl), 31 Oct 2014
The hepatic transcription of apolipoprotein A-I (ApoA-I), apolipoproteinB (ApoB), and adiponectin was significantly higher in AA broilers than in BJY broilers.
Paraoxonase 1 and HDL maturation.
Menini et al., Vallejo, United States. In Clin Chim Acta, 24 Oct 2014
The crucial phase will be achieved when human kinetic studies (both in the fasting and the post-prandial state) on HDL -PON1, apoA-I and lipids fate in the circulation are carried out.
ATP-Binding Cassette Transporter A1: From metabolism to neurodegeneration.
Lefterov et al., Pittsburgh, United States. In Neurobiol Dis, Jun 2014
UNLABELLED: ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE).
Searching for a successful HDL-based treatment strategy.
Fogelman et al., In Biochim Biophys Acta, Jan 2014
This brief review focuses on a different strategy, which is based on the use of 18-amino acid apoA-I-mimetic peptides.
Effects of miR-33a-5P on ABCA1/G1-Mediated Cholesterol Efflux under Inflammatory Stress in THP-1 Macrophages.
Ruan et al., Chongqing, China. In Plos One, Dec 2013
ApoA-I-mediated cholesterol efflux was examined using the fluorescent sterol (BODIPY-cholesterol).
ApoA-I/HDL Generation and Intracellular Cholesterol Transport through Cytosolic Lipid-Protein Particles in Astrocytes.
Michikawa et al., Nagoya, Japan. In J Lipids, Dec 2013
Exogenous apolipoprotein A-I (apoA-I) associates with ATP-binding cassette transporter A1 (ABCA1) on the cell surface of astrocytes like various peripheral cells and enhances the translocation of newly synthesized cholesterol from the endoplasmic reticulum/Golgi apparatus (ER/Golgi) to the cytosol.
Orp8 Deficiency in Bone Marrow-Derived Cells Reduces Atherosclerotic Lesion Progression in LDL Receptor Knockout Mice.
Van Eck et al., Leiden, Netherlands. In Plos One, Dec 2013
ORP8 downregulates ABCA1 expression in macrophages and cellular cholesterol efflux to apolipoprotein A-I.
Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.
Melbye et al., Copenhagen, Denmark. In Jama, Sep 2013
P = 1.9 × 10(-10)), is located 301 bases downstream of the apolipoprotein A-I (APOA1) gene and is correlated (r2 between 0.46 and 0.80) with SNPs previously found to be associated with levels of circulating cholesterol.
Control of angiogenesis by AIBP-mediated cholesterol efflux.
Miller et al., San Diego, United States. In Nature, Jul 2013
To prevent cholesterol overload, ATP-binding cassette (ABC) transporters mediate cholesterol efflux from the cells to apolipoprotein A-I (apoA-I) and the apoA-I-containing high-density lipoprotein (HDL).
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival.
Singh-Jasuja et al., Tübingen, Germany. In Nat Med, 2012
Furthermore, among six predefined populations of myeloid-derived suppressor cells, two were prognostic for overall survival, and among over 300 serum biomarkers, we identified apolipoprotein A-I (APOA1) and chemokine (C-C motif) ligand 17 (CCL17) as being predictive for both immune response to IMA901 and overall survival.
Lipid-related markers and cardiovascular disease prediction.
Danesh et al., In Jama, 2012
OBJECTIVE: To determine whether adding information on apolipoprotein B and apolipoprotein A-I, lipoprotein(a), or lipoprotein-associated phospholipase A2 to total cholesterol and high-density lipoprotein cholesterol (HDL-C) improves cardiovascular disease (CVD) risk prediction.
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis.
Rader et al., Philadelphia, United States. In N Engl J Med, 2011
RESULTS: The levels of HDL cholesterol and apolipoprotein A-I were significant determinants of cholesterol efflux capacity but accounted for less than 40% of the observed variation.
Rapid incorporation of functional rhodopsin into nanoscale apolipoprotein bound bilayer (NABB) particles.
Sakmar et al., New York City, United States. In J Mol Biol, 2008
The NABB system using engineered zebrafish apo A-I is a native-like membrane mimetic system for G-protein-coupled receptors.
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