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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 10 Dec 2014.

Apolipoprotein A-Ia

apolipoprotein A-I, apoA-I
Top mentioned proteins: HDL, Apo, CAN, HAD, fibrillin-1
Papers on apolipoprotein A-I
Correlation of apolipoprotein A-I kinetics with survival and response to first-line platinum-based chemotherapy in advanced non-small cell lung cancer.
New
Miao et al., Nanjing, China. In Med Oncol, 31 Jan 2015
The aim of this study was to determine whether apolipoprotein A-I (ApoA-I) kinetics predict the overall survival in patients with advanced-stage non-small cell lung cancer (NSCLC) during platinum-based first-line therapy.
Adipocyte Phospholipid Transfer Protein and Lipoprotein Metabolism.
New
Jiang et al., Los Angeles, United States. In Arterioscler Thromb Vasc Biol, 04 Jan 2015
PLTP ablation resulted in a significant reduction in plasma PLTP activity (22%) and in high-density lipoprotein, cholesterol (21%), phospholipid (20%), and apolipoprotein A-I (33%) levels, but had no effect on nonhigh-density lipoprotein levels in comparison with those of PLTP-Flox-ΔNeo controls.
Alginic Acid Cell Entrapment: A Novel Method for Measuring In Vivo Macrophage Cholesterol Homeostasis.
New
Reardon et al., Chicago, United States. In J Lipid Res, 01 Jan 2015
Both normal and cholesterol loaded macrophages undergo measureable changes in cell cholesterol when injected into wild-type, apoA-I, LDL-receptor, or apoE deficient mice.
High-density lipoprotein and atherosclerosis: Roles of lipid transporters.
Review
New
Saku et al., Fukuoka, Japan. In World J Cardiol, 26 Nov 2014
HDL therapies that use injections of reconstituted HDL, apoA-I mimetics, or full-length apoA-I have shown dramatic effectiveness.
Apolipoprotein A-I expression suppresses COX-2 expression by reducing reactive oxygen species in hepatocytes.
New
Wang et al., Beijing, China. In Biochem Biophys Res Commun, 24 Nov 2014
Apolipoprotein A-I (apoA-I) accepts cellular cholesterol and phospholipids transported by ATP-binding cassette transporter A1 to generate nascent high density lipoprotein particles.
Paraoxonase 1 and HDL maturation.
Review
New
Menini et al., Vallejo, United States. In Clin Chim Acta, Oct 2014
The crucial phase will be achieved when human kinetic studies (both in the fasting and the post-prandial state) on HDL -PON1, apoA-I and lipids fate in the circulation are carried out.
ATP-Binding Cassette Transporter A1: From metabolism to neurodegeneration.
Review
New
Lefterov et al., Pittsburgh, United States. In Neurobiol Dis, Jun 2014
UNLABELLED: ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE).
The structure/function of apoprotein A-I mimetic peptides: an update.
Review
New
Reardon et al., Chicago, United States. In Curr Opin Endocrinol Diabetes Obes, Apr 2014
PURPOSE OF REVIEW: To review recent advances in our understanding of the mechanism of action of apoprotein A-I (apoA-I) mimetic peptides and improved methods for the oral delivery of peptides.
ApoA-I/HDL Generation and Intracellular Cholesterol Transport through Cytosolic Lipid-Protein Particles in Astrocytes.
Review
New
Michikawa et al., Nagoya, Japan. In J Lipids, Dec 2013
Exogenous apolipoprotein A-I (apoA-I) associates with ATP-binding cassette transporter A1 (ABCA1) on the cell surface of astrocytes like various peripheral cells and enhances the translocation of newly synthesized cholesterol from the endoplasmic reticulum/Golgi apparatus (ER/Golgi) to the cytosol.
Incubation of MDCO-216 (ApoA-IMilano/POPC) with Human Serum Potentiates ABCA1-Mediated Cholesterol Efflux Capacity, Generates New Prebeta-1 HDL, and Causes an Increase in HDL Size.
New
Wijngaard et al., Zürich, Switzerland. In J Lipids, Dec 2013
Native 2D electrophoresis followed by immunoblotting with an apoA-I antibody, which also detects ApoA-I Milano, confirmed the increase in prebeta-1 HDL upon incubation at 37°C.
Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.
New
Impact
Melbye et al., Copenhagen, Denmark. In Jama, Sep 2013
P = 1.9 × 10(-10)), is located 301 bases downstream of the apolipoprotein A-I (APOA1) gene and is correlated (r2 between 0.46 and 0.80) with SNPs previously found to be associated with levels of circulating cholesterol.
Control of angiogenesis by AIBP-mediated cholesterol efflux.
New
Impact
Miller et al., San Diego, United States. In Nature, Jul 2013
To prevent cholesterol overload, ATP-binding cassette (ABC) transporters mediate cholesterol efflux from the cells to apolipoprotein A-I (apoA-I) and the apoA-I-containing high-density lipoprotein (HDL).
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival.
Impact
Singh-Jasuja et al., Tübingen, Germany. In Nat Med, 2012
Furthermore, among six predefined populations of myeloid-derived suppressor cells, two were prognostic for overall survival, and among over 300 serum biomarkers, we identified apolipoprotein A-I (APOA1) and chemokine (C-C motif) ligand 17 (CCL17) as being predictive for both immune response to IMA901 and overall survival.
Lipid-related markers and cardiovascular disease prediction.
Impact
Danesh et al., In Jama, 2012
OBJECTIVE: To determine whether adding information on apolipoprotein B and apolipoprotein A-I, lipoprotein(a), or lipoprotein-associated phospholipase A2 to total cholesterol and high-density lipoprotein cholesterol (HDL-C) improves cardiovascular disease (CVD) risk prediction.
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis.
Impact
Rader et al., Philadelphia, United States. In N Engl J Med, 2011
RESULTS: The levels of HDL cholesterol and apolipoprotein A-I were significant determinants of cholesterol efflux capacity but accounted for less than 40% of the observed variation.
Rapid incorporation of functional rhodopsin into nanoscale apolipoprotein bound bilayer (NABB) particles.
GeneRIF
Sakmar et al., New York City, United States. In J Mol Biol, 2008
The NABB system using engineered zebrafish apo A-I is a native-like membrane mimetic system for G-protein-coupled receptors.
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