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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

APLNR apelin receptor

apelin receptor
Top mentioned proteins: apelin, SRA, Angiotensin II, V1a, HAD
Papers on apelin receptor
Water deprivation-partial rehydration induces sensitization of sodium appetite and alteration of hypothalamic transcripts.
New
De Luca et al., São Paulo, Brazil. In Am J Physiol Regul Integr Comp Physiol, Feb 2016
We found that repeated WD-PR, besides enhancing spontaneous and induced 0.3 M NaCl intake, increased the hypothalamic expression of angiotensinogen, aminopeptidase N, and apelin receptor transcripts (43%, 60%, and 159%, respectively) in HTZ at the end of the third WD-PR.
Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart.
New
Kerkelä et al., Oulu, Finland. In Basic Res Cardiol, Jan 2016
The G protein-coupled apelin receptor regulates important processes of the cardiovascular homeostasis, including cardiac development, cardiac contractility, and vascular tone.
Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging.
New
Bonnet et al., Illkirch-Graffenstaden, France. In Chemistry, Jan 2016
Various fluorescent probes were readily synthesized, enabling the rapid optimization of their affinities for the apelin receptor.
Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction.
New
Naka et al., Suita, Japan. In Cardiovasc Res, Jan 2016
Consistently, the expression of apelin receptor was reduced in LRG-/-mice, implyingthat the impaired angiogenic activity is associated with adverse cardiacremodellingin LRG-/-mice.
Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia.
New
Hamano et al., Ube, Japan. In Sci Rep, Dec 2015
Interestingly, expression of an apelin receptor, APJ, in PBMNC was increased under hypoxia but not under normoxia.
Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.
Review
New
Runyon et al., United States. In J Med Chem, Nov 2015
Apelin peptides and the apelin receptor represent a relatively new therapeutic axis for the potential treatment of cardiovascular disease.
Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice.
New
Yu et al., Decatur, United States. In Asn Neuro, Sep 2015
Western blot analyses showed upregulated levels of apelin, apelin receptor APLNR, and Bcl-2 and decreased caspase-3 activation in the apelin-13-treated brain.
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system.
Review
New
Davenport et al., Cambridge, United Kingdom. In Trends Pharmacol Sci, Sep 2015
Remarkably, a peptide, Elabela/Toddler, that has little sequence similarity to apelin, has been proposed as a second endogenous apelin receptor ligand and is encoded by a gene from a region of the genome previously classified as 'non-coding'.
Apelin and New-Onset Diabetes After Transplant in Living Kidney Allograft Recipients.
New
Foudas et al., Al Manşūrah, Egypt. In Exp Clin Transplant, Aug 2015
Circulating serum apelin suppresses insulin secretion by binding to the G-protein-coupled apelin receptor on B cells of islets of Langerhans.
The apelin receptor: physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR.
Review
Rainey et al., Halifax, Canada. In Biochem Cell Biol, 2014
The apelin receptor (AR or APJ) is a class A (rhodopsin-like) G-protein-coupled receptor with wide distribution throughout the human body.
Directed Molecular Evolution of an Engineered Gammaretroviral Envelope Protein with Dual Receptor Use Shows Stable Maintenance of Both Receptor Specificities.
Pedersen et al., Paris, France. In J Virol, 2014
The apelin receptor has previously been shown to function as a coreceptor for HIV-1, and thus, adaptation of the viral vector to this receptor is of significant interest.
Apelin receptor: its responsiveness to stretch mechanisms and its potential for cardiovascular therapy.
Review
Koch et al., Philadelphia, United States. In Expert Rev Cardiovasc Ther, 2014
It has recently been demonstrated that the apelin receptor (APJ) plays a significant role in mediating the stretch response within the heart in a G-protein-independent and β-arrestin-dependent fashion.
The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis.
Review
Pope et al., Bristol, United Kingdom. In J Endocrinol, 2013
The apelin receptor (APJ; gene symbol APLNR) is a member of the G protein-coupled receptor gene family.
A mesoderm-derived precursor for mesenchymal stem and endothelial cells.
Impact
Slukvin et al., Madison, United States. In Cell Stem Cell, 2011
Using human embryonic stem cells directed toward mesendodermal differentiation, we show that mesenchymal stem/stromal cells (MSCs) originate from a population of mesodermal cells identified by expression of apelin receptor.
International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function.
Review
Impact
Davenport et al., Cambridge, United Kingdom. In Pharmacol Rev, 2010
This review outlines the official International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification nomenclature, designating the receptor protein as the apelin receptor, together with current knowledge of its pharmacology, distribution, and functions.
Apelin and APJ receptor expression in granulosa and theca cells during different stages of follicular development in the bovine ovary: Involvement of apoptosis and hormonal regulation.
GeneRIF
Miyamoto et al., Obihiro, Japan. In Anim Reprod Sci, 2009
APJ receptor in granulosa cells and both apelin and the APJ receptor in theca tissues are expressed in bovine ovary.
The expression of apelin and its receptor APJ during different physiological stages in the bovine ovary.
GeneRIF
Berisha et al., Freising, Germany. In Int J Biol Sci, 2008
The data suggest that apelin/APJ system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.
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