De Luca et al., São Paulo, Brazil. In Am J Physiol Regul Integr Comp Physiol, Feb 2016
We found that repeated WD-PR, besides enhancing spontaneous and induced 0.3 M NaCl intake, increased the hypothalamic expression of angiotensinogen, aminopeptidase N, and apelin receptor transcripts (43%, 60%, and 159%, respectively) in HTZ at the end of the third WD-PR.
Davenport et al., Cambridge, United Kingdom. In Trends Pharmacol Sci, Sep 2015
Remarkably, a peptide, Elabela/Toddler, that has little sequence similarity to apelin, has been proposed as a second endogenous apelin receptor ligand and is encoded by a gene from a region of the genome previously classified as 'non-coding'.
Koch et al., Philadelphia, United States. In Expert Rev Cardiovasc Ther, 2014
It has recently been demonstrated that the apelin receptor (APJ) plays a significant role in mediating the stretch response within the heart in a G-protein-independent and β-arrestin-dependent fashion.
Slukvin et al., Madison, United States. In Cell Stem Cell, 2011
Using human embryonic stem cells directed toward mesendodermal differentiation, we show that mesenchymal stem/stromal cells (MSCs) originate from a population of mesodermal cells identified by expression of apelin receptor.
Davenport et al., Cambridge, United Kingdom. In Pharmacol Rev, 2010
This review outlines the official International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification nomenclature, designating the receptor protein as the apelin receptor, together with current knowledge of its pharmacology, distribution, and functions.