Annexin A4 and cancer.
Dalian, China. In Clin Chim Acta, Aug 2015
Annexin A4 (Anxa4) is one of the Ca(2+)-regulated and phospholipid-binding annexin superfamily proteins.
Cystatin B as a potential diagnostic biomarker in ovarian clear cell carcinoma.
Tokyo, Japan. In Int J Oncol, Apr 2015
Based on hierarchical clustering that revealed a marked distinction in the expression levels of cystatin B (CYTB) and Annexin A4 (ANXA4) in CCC relative to the other subtypes, we focused the study on CYTB and ANXA4 expression in EOCs by IHC, RT-qPCR and western blot analyses using tissue specimens and cultured cells.
[Proteomics analysis for Helicobacter pylori-infected gastric mucosa].
Seoul, South Korea. In Korean J Gastroenterol, 2014
The altered protein expressions were then identified by mass spectrometry and validated by Western blotting and immunohistochemistry. RESULTS: On mass spectrometry using MALDI TOF™ Analyzer, the up-regulation of Keratin 1, ezrin, adenosine triphosphate (ATP) synthase subunit alpha mitochondrial isoform c, Keratin type I cytoskeletal 19, and Keratin type I cytoskeletal 9 were identified; in contrast, 71 kd heat shock cognate protein, ATP synthase subunit alpha mitochondrial precursor, and annexin IV were down-regulated.
Genomic and proteomic approaches to renal cell carcinoma.
Napoli, Italy. In J Nephrol, 2011
Among others, vimentin, heat shock protein 27 (Hsp27), annexin IV and serum amyloid alpha-1 (SAA-1) have been identified as reliable markers of RCC that are potentially useful in the clinical setting.
Targeting annexin A4 to counteract chemoresistance in clear cell carcinoma of the ovary.
Ibaraki, Japan. In Expert Opin Ther Targets, 2010
AREAS COVERED IN THIS REVIEW: An overview of the clinical characteristics of ovarian CCC; the role of annexin family proteins in tumor development and progression; the role of annexin A4 in enhancing cellular drug resistance; recent studies linking annexin A4 overexpression to chemoresistance in tumors of ovarian CCC.