Yang et al., Montréal, Canada. In Structure, May 2015
We have recently demonstrated that ankyrin repeats of ANKRA2 and the paralogous bare lymphocyte syndrome transcription factor RFXANK recognize PxLPxL/I motifs shared by megalin, three histone deacetylases, and RFX5.
The objective was to determine whether single nucleotide polymorphisms (SNPs) in the ANKRA2 and CD180 genes are associated with incidence of bovine respiratory disease (BRD) and presence of Mycobacterium avium subsp.
Fujii-Kuriyama et al., Tsukuba, Japan. In Biochem Biophys Res Commun, 2008
The inhibitory activity of AhRR is sensitive to a histone deacetylase (HDAC) inhibitor, trichostatin A. By using the yeast two-hybrid screening method with the C-terminal sequence of AhRR as bait, we identified a binding partner, Ankyrin-repeat protein2 (ANKRA2), a protein known to interact with HDAC4 and HDAC5.
Olson et al., Westminster, United States. In Mol Biol Cell, 2006
Class II histone deacetylases (HDACs)4 and HDAC5 interact with the ankyrin repeats of ANKRA2 and regulatory factor X-associated ankyrin-containing protein and, through association with RFXANK, repress MHC II promoter activation