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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Anillin, actin binding protein

anillin, ANLN, Scraps
Top mentioned proteins: Actin, CAN, Midline, RhoA, V1a
Papers on anillin
Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.
Goshima et al., Nagoya, Japan. In Mol Biol Cell, Feb 2016
Augmin depletion reduced the accumulation of anillin, a contractile ring regulator at the cell equator, yet centrosomal MTs were sufficient to mediate RhoA activation at the furrow.
Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division.
Canman et al., Paris, France. In J Cell Biol, Feb 2016
We found that the cortical PAR proteins are required for the retention of anillin and septin in the anterior pole, which are cytokinesis proteins that our genetic data suggest act as inhibitors of F-actin at the contractile ring.
Comparative biology of cell division in the fission yeast clade.
Oliferenko et al., London, United Kingdom. In Curr Opin Microbiol, Dec 2015
Recent work on another member of the same genus, Schisozaccharomyces japonicus, suggests that S. pombe may have evolved an unusual division site placement mechanism based on a recently duplicated anillin paralog.
The DYRK-family kinase Pom1 phosphorylates the F-BAR protein Cdc15 to prevent division at cell poles.
Martin et al., Lausanne, Switzerland. In J Cell Biol, Dec 2015
In rod-shaped fission yeast Schizosaccharomyces pombe cells, division at midcell is achieved through positive Mid1/anillin-dependent signaling emanating from the central nucleus and negative signals from the dual-specificity tyrosine phosphorylation-regulated kinase family kinase Pom1 at the cell poles.
The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L.
Murata et al., Tsu, Japan. In Oncotarget, Dec 2015
Two potential targets of miR-497, ANLN (anillin, actin-binding protein) and HSPA4L (heat shock 70 kDa protein 4-like), both of which were overexpressed in NPC tissues, were negatively regulated by miR-497 mimic in NPC cell lines.
Sequencing of candidate genes in Dominican families implicates both rare exonic and common non-exonic variants for carotid intima-media thickness at bifurcation.
Sacco et al., Miami, United States. In Hum Genet, Oct 2015
Through linkage and tagSNP-based association studies in 100 Dominican Republic (DR) families, we previously identified ANLN and AOAH (7p14.3)
PAR-4 and anillin regulate myosin to coordinate spindle and furrow position during asymmetric division.
Michaux et al., Rennes, France. In J Cell Biol, Oct 2015
We find that PAR-4/LKB1 impinges on myosin via two pathways, an anillin-dependent pathway that also responds to the cullin CUL-5 and an anillin-independent pathway involving the kinase PIG-1/MELK.
Identification of ANLN as ETV6 partner gene in recurrent t(7;12)(p15;p13): a possible role of deregulated ANLN expression in leukemogenesis.
Santos et al., São Paulo, Brazil. In Mol Cancer, 2014
We herein report that the t(7;12)(p15;p13) fuses ETV6 to ANLN, a gene not previously implicated in the pathogenesis of hematological malignancies, and we demonstrate that this translocation leads to high expression of the fusion transcript in the myeloid and lymphoid lineages.
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.
Sahai et al., London, United Kingdom. In Nat Cell Biol, 2013
YAP regulates the expression of several cytoskeletal regulators, including ANLN and DIAPH3, and controls the protein levels of MYL9 (also known as MLC2).
Mid1/anillin and the spatial regulation of cytokinesis in fission yeast.
Paoletti et al., Paris, France. In Cytoskeleton (hoboken), 2012
Division plane position in this unicellular rod-shaped organism, which divides by the assembly and constriction of a medially placed actomyosin ring, largely depends on the anillin-like protein Mid1.
Contractile-ring assembly in fission yeast cytokinesis: Recent advances and new perspectives.
Wu et al., Columbus, United States. In Cytoskeleton (hoboken), 2012
IQGAP Rng2 and myosin essential light chain Cdc4 are recruited by the anillin-like protein Mid1, followed by the addition of other cytokinesis node proteins.
An anillin-Ect2 complex stabilizes central spindle microtubules at the cortex during cytokinesis.
Piekny et al., Montréal, Canada. In Plos One, 2011
Data supports an analogous function for the anillin-Ect2 complex in human cells and one hypothesis is that this complex has functionally replaced the Drosophila anillin-RacGAP50C complex.
Citron kinase controls abscission through RhoA and anillin.
Di Cunto et al., Torino, Italy. In Mol Biol Cell, 2011
CIT-K is capable of physically and functionally interacting with the actin-binding protein anillin.
Anillin expression is a marker of favourable prognosis in patients with renal cell carcinoma.
Vaarala et al., Oulu, Finland. In Oncol Rep, 2011
Cytoplasmic anillin expression is a marker of favourable prognosis in renal cell carcinoma patients.
Mechanisms controlling division-plane positioning.
Paoletti et al., Paris, France. In Semin Cell Dev Biol, 2010
In this system, spatial regulations target a major factor controlling the position of the division plane, the anillin-like protein Mid1.
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis.
Narumiya et al., Kyoto, Japan. In Mol Biol Cell, 2010
Results show that targeting of mDia2 to the cleavage furrow requires not only its binding to RhoA but also its diaphanous-inhibitory domain, and identify anillin as a novel mDia2 interaction partner.
A spatial gradient coordinates cell size and mitotic entry in fission yeast.
Nurse et al., New York City, United States. In Nature, 2009
This network is located at cortical nodes in the middle of interphase cells, and these nodes contain the Cdk1 inhibitor Wee1, the Wee1-inhibitory kinases Cdr1 (also known as Nim1) and Cdr2, and the anillin-like protein Mid1.
NBL1 and anillin (ANLN) genes over-expression in pancreatic carcinoma.
Jarzab et al., Katowice, Poland. In Folia Histochem Cytobiol, 2008
This study was to establish if ANLN was a molecular marker for pancreatic cancer.
Anillin: a pivotal organizer of the cytokinetic machinery.
O'Farrell et al., San Francisco, United States. In Biochem Soc Trans, 2008
Accordingly, many proteins, including the putative scaffold protein anillin, localize to the cleavage furrow and are required for cytokinesis, but how they function together is poorly understood.
The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage.
Barral et al., Zürich, Switzerland. In Cell, 2006
NoCut depends on the Aurora kinase Ipl1 and the anillin-related proteins Boi1 and Boi2, which localize to the site of cleavage in an Ipl1-dependent manner and act as abscission inhibitors.
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