Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growthmore suppliers
In Cell Cycle, 2010
... (#ab10433; Abcam), anti-Cathepsin B (#sc-13985 (FL-339); Santa Cruz Biotech), anti-OXPHOS (#MS601; Mitosciences), anti-β actin (#A5441, Sigma), anti-phospho-AMPK (#2531, Cell Signaling), anti-AMPK (#2532, Cell Signaling), ...
Leptin signalling pathways in hypothalamic neurons.
Seoul, South Korea. In Cell Mol Life Sci, Feb 2016
The signaling pathways known to mediate the actions of leptin include JAK-STAT signaling, PI3K-Akt-FoxO1 signaling, SHP2-ERK signaling, AMPK signaling, and mTOR-S6K signaling.
Changes in one-carbon metabolism after duodenal-jejunal bypass surgery.
Dublin, Ireland. In Am J Physiol Endocrinol Metab, Feb 2016
In particular, the AMP:ATP ratio and phosphorylation of AMP-activated protein kinase increased after DJB surgery, which led to enhanced energy production and increased catabolic pathway activity, such as fatty acid oxidation and glucose transport.
AMPK Keeps Tumor Cells from Starving to Death.
More papers using
Los Angeles, United States. In Cell Stem Cell, Dec 2015
They find that inhibition of the metabolic stress sensor AMP-activated protein kinase (AMPK) led to deranged glucose metabolism and redox homeostasis, resulting in reduced leukemic progression that was further attenuated by dietary restriction.
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
In Diabetes, 2005
... Akt, phospho-Akt (Ser 473), phospho-tyrosine, AMP-activated protein kinase (AMPK)α, phospho-AMPK (Thr 172), horseradish peroxidase anti-rabbit, and anti-mouse IgG were obtained from Cell Signaling Technology (Beverly, MA) ... A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain.
In PLoS ONE, 2001
... Cruz (Santa Cruz, CA), antibodies against PAS, ERK, phospho-ERK, Akt, phospho-Akt (T308 and S473), AMPK, phospho-AMPK, and phosphotyrosine from Cell Signaling Technology (Danvers, MA), anti-AS160 ... Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells.
In PLoS ONE, 1995
... IR, IRS1 were purchased from Upstate Biotechnology (Lake Placid, NY), pAkt (Ser473), pErk, pAMPK (Thr172), AMPK, pACC (Ser79), ACC were purchased from Cell Signaling Technology (Beverly, MA), LKB1, ...