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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Adrenergic receptor, alpha 1a

alpha1A-adrenergic receptor, Adra1a
Top mentioned proteins: CACNA1A, Alpha-1, HAD, POLYMERASE, AGE
Papers on alpha1A-adrenergic receptor
Could α1-adrenoceptors and androgen receptors be modified by sexual maturation and testosterone in the rat testicular capsule?
New
Avellar et al., São Paulo, Brazil. In Life Sci, Dec 2015
Androgen receptor and α1-adrenoceptor (Adra1a, Adra1b, and Adra1d) mRNA levels were similar in testicular capsule from all experimental groups.
Sustained in vivo blockade of α₁-adrenergic receptors prevented some of stress-triggered effects on steroidogenic machinery in Leydig cells.
Andric et al., Novi Sad, Serbia. In Am J Physiol Endocrinol Metab, 2013
In this signaling scenario, stress-induced stimulation of Adra1a/Adra1b/Adrbk1 and Hsd11b2 (the unidirectional oxidase with high affinity to inactivate glucocorticoids) was not changed.
Plasticity of cardiovascular function in snapping turtle embryos (Chelydra serpentina): chronic hypoxia alters autonomic regulation and gene expression.
Crossley et al., Denton, United States. In Am J Physiol Regul Integr Comp Physiol, 2013
However, expression of adrenergic receptor mRNA (Adrb1, Adra1a, Adra2c) and growth factor mRNA (Igf1, Igf2, Igf2r, Pdgfb) was lowered in H10 embryos.
Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer.
GeneRIF
Pfleger et al., Perth, Australia. In J Biol Chem, 2012
We have provided the first evidence for specific heteromerization between the alpha(1A)-adrenoceptor (alpha(1A)AR) and CXC chemokine receptor 2 (CXCR2) in live cells.
Nuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytes.
GeneRIF
O'Connell et al., Sioux Falls, United States. In Cell Signal, 2012
Co-localization of the alpha1-subtypes at the nuclei in adult cardiac myocytes facilitated the formation of receptor oligomers that could affect receptor signaling.
Functional analysis of a novel antagonistic antibody against the short epitope of the α1A-adrenergic receptor.
Liao et al., Wuhan, China. In Cardiovasc Res, 2012
AIMS: The alpha1A-adrenergic receptor (α1A-AR) regulates various vascular functions and participates in the pathogenesis of primary hypertension.
Long-term α1A-adrenergic receptor stimulation improves synaptic plasticity, cognitive function, mood, and longevity.
GeneRIF
Perez et al., Grand Forks, United States. In Mol Pharmacol, 2011
Activation of the adrenergic receptor alpha 1a subtype enhances learning and memory and has antidepressant and antianxiety effects.
Age-dependent regulation of depression-like behaviors through modulation of adrenergic receptor α₁A subtype expression revealed by the analysis of interleukin-1 receptor antagonist knockout mice.
GeneRIF
Iwakura et al., Tokyo, Japan. In Neuroscience, 2011
sustained activation of IL-1 signaling....affects the expression of the ARalpha(1A) subtype..and that modification of adrenergic signaling by the IL-1 system may ultimately cause significant psychiatric abnormalities such as depression
WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.
GeneRIF
Hadchouel et al., Paris, France. In Hypertension, 2011
Findings uncover a vascular signaling pathway linking alpha(1)-adrenergic receptors and pressure to WNK1, SPAK, and NKCC1 and may, thus, significantly broaden the comprehension of the regulatory mechanisms of vascular tone in arterial hypertension.
Complications of cataract surgery in patients with BPH treated with alpha 1A-blockers.
Review
Wylegala et al., Katowice, Poland. In Cent European J Urol, 2010
Cataract is treated surgically and it has been reported that there may be an association between use of alpha-blockers for BPH, particularly alpha1A-adrenergic receptor selective drugs, and complications of cataract surgery known as Intraoperative Floppy Iris Syndrome (IFIS).
Silodosin: a selective alpha1A-adrenergic receptor antagonist for the treatment of benign prostatic hyperplasia.
Review
Benzeroual et al., Long Beach, United States. In Clin Ther, 2009
BACKGROUND: Silodosin is a new alpha(1)-adrenergic receptor antagonist that is selective for the alpha(1A)-adrenergic receptor.
Effects of estrogen, raloxifene and levormeloxifene on alpha1A-adrenergic receptor expression.
Lin et al., San Francisco, United States. In J Urol, 2008
PURPOSE: We investigated the effect of estrogen, raloxifene and levormeloxifene on alpha1A-adrenergic receptor expression.
Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes.
GeneRIF
O'Connell et al., Sioux Falls, United States. In Circ Res, 2008
Nuclear alpha1A-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes.
GATA4 is a survival factor in adult cardiac myocytes but is not required for alpha1A-adrenergic receptor survival signaling.
GeneRIF
O'Connell et al., Sioux Falls, United States. In Am J Physiol Heart Circ Physiol, 2008
GATA4 is a survival factor in adult cardiac myocytes but is not required for alpha1A-adrenergic receptor survival signaling.
An investigation of the alpha1A-adrenergic receptor gene and antipsychotic-induced side-effects.
de Leon et al., London, United Kingdom. In Hum Psychopharmacol, 2008
Antipsychotic treatment is hampered by the induction of side-effects such as tardive dyskinesia (TD), weight gain, sedation and extrapyramidal side-effects (EPS).
Heightened alpha1A-adrenergic receptor activity suppresses ischaemia/reperfusion-induced Ins(1,4,5)P3 generation in the mouse heart: a comparison with ischaemic preconditioning.
Woodcock et al., Melbourne, Australia. In Clin Sci (lond), 2008
Reperfusion of ischaemic rat or mouse hearts causes NE [noradrenaline ('norepinephrine')] release, stimulation of alpha(1)-ARs (alpha(1)-adrenergic receptors), PLC (phospholipase C) activation, Ins(1,4,5)P(3) generation and the development of arrhythmias.
Association of alpha1a-adrenergic receptor polymorphism and blood pressure phenotypes in the Brazilian population.
Krieger et al., São Paulo, Brazil. In Bmc Cardiovasc Disord, 2007
BACKGROUND: The alpha1A-adrenergic receptor (alpha1A-AR) regulates the cardiac and peripheral vascular system through sympathetic activation.
Localization of the mouse alpha1A-adrenergic receptor (AR) in the brain: alpha1AAR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors.
Perez et al., Cleveland, United States. In J Comp Neurol, 2006
alpha(1)-Adrenergic receptors (ARs) are not well defined in the central nervous system.
Review of orthostatic tests on the safety of tamsulosin, a selective alpha1A-adrenergic receptor antagonist, shows lack of orthostatic hypotensive effects.
Review
Ito et al., Tokyo, Japan. In J Int Med Res, 2001
Two phase III studies with tamsulosin, a selective alpha1A-adrenergic receptor antagonist, were conducted to evaluate the safety and efficacy of the standard treatment doses of 0.4 mg/day and 0.8 mg/day in patients with symptoms of benign prostatic hyperplasia (BPH).
Tamsulosin for the treatment of benign prostatic hypertrophy.
Review
Lee, Downers Grove, United States. In Ann Pharmacother, 2000
DATA SYNTHESIS: Tamsulosin, a uroselective alpha1A-adrenergic receptor antagonist, relaxes smooth muscle in the prostate and bladder neck, thereby enhancing bladder emptying.
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